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Position available: Sleep & EEG in Huntington's disease

Research Assistant (Fixed Term): Sleep and EEG in transgenic mouse models of Huntington's disease

Department/Location: Department of Physiology, Development and Neuroscience

Salary: £25,023-£28,982

Reference: PM08421

Category: Research

Published: 18 February 2016

Closing date: 1 April 2016

The post is part of a project funded by CHDI Inc, a charitable foundation based in the USA that funds research into Huntington's disease (HD). HD is an incurable neurodegenerative genetic disorder that causes progressive deterioration of motion and cognitive function, as well as changes in psychiatric domains such as anxiety and depression. Recently, sleep and EEG abnormalities have been identified in HD patients as well as in mouse models of HD. The purpose of this project is to use these EEG measures in HD mice as 'readouts' for investigating the therapeutic potential of both existing and future treatment options of HD. The results will contribute to a larger project led by Professor Jenny Morton studying the effects of neurodegeneration in HD and interventions to prevent progression of the disease.

You will be part of a research team investigating sleep-wake behaviour and EEG in normal and transgenic mouse models of HD, based in the Department of Physiology, Development and Neuroscience, University of Cambridge.

The successful applicant will be a careful and methodical worker who is self-motivated and able to conduct experiments and analyse data independently. Careful observation skills and accurate record keeping are essential. Applicants will need to hold a Home Office personal licence. If the successful candidate does not have all the skills required, training will be given.

Applicants must have a BSc degree (or equivalent), preferably with a background in Neuroscience. Experience in analysing rodent EEG traces, assisting with EEG/EMG surgery, or familiarity with deep brain recordings and signal processing would be an advantage. The post will require some weekend work and a flexible approach to working hours.

Fixed-term: The funds for this post are available for 2 years in the first instance. This is a full-time post with immediate availability.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application. If you upload any additional documents, which have not been requested, we will not be able to consider these as part of your application.

The closing date for applications is midnight on Friday 1 April 2016. Interviews are likely to be held week commencing 18 April 2016. For further information about the post, email Professor Jenny Morton (

Please quote reference PM08421 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Further information

Posted on 01/03/2016

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