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Slow, slow, quick quick, slow: Scientists discover how proteins in the brain build-up rapidly in Alzheimer’s disease
Cambridge researchers have identified – and shown that it may be possible to control – the mechanism that leads to the rapid build-up of the disease-causing ‘plaques’ that are characteristic of Alzheimer’s disease.
The ability of biological molecules, such as our DNA, to replicate themselves is the foundation of life. It is a process that usually involves complex cellular machinery. However, certain protein structures manage to replicate without any additional assistance, such as the small, disease-causing protein fibres – fibrils – that are involved in neurodegenerative disorders, including Alzheimer’s and Parkinson’s.
Posted on 22/07/2016
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