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3 year Post Doctoral position available in MRC LMB - Closing date June 6th
Postdoctoral Scientist: brain slice electrophysiology
Closing date: 06 Jun 2012
Vacancy Reference No: IRC54544
Salary: £26,022 to £28,178 per annum
Address: MRC Laboratory of Molecular Biology, Cambridge, Group of Dr Michael Hastings, FRS FMedSci
Duration: 3 years
An experienced brain slice electrophysiologist is required to work within a multidisciplinary research group investigating the molecular neurobiology of circadian timekeeping in the mammalian brain. Approaches include patchclamp recording (acute and organotypic brain slices), optogenetic & chemogenetic manipulation of neuronal physiology, real-time bioluminescent imaging of circadian gene expression, and molecular genetic and pharmacological manipulation of tissues.
You should have a PhD in a biological subject and have experience of brain slice patch clamp electrophysiology. You should have an interest in developing new procedures (chemo- /opto-genetics) and working collaboratively with molecular biologists and neurobiologists to devise new approaches to elucidating the interplay between electrical activities of the mammalian brain and circadian pacemaking at the level of gene expression networks. Experience of working with brain slice cultures, virally mediated gene expression, optogenetics, neuropharmacology, neuroanatomy is desirable.
Posted on 29/05/2012
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