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Defeat Dementia in Down's Syndrome - Recruitment film

Researchers from the Department of Psychiatry have launched a recruitment film to better explain facets of their Alzheimer’s disease (AD) in Down syndrome (DS) study to participants who may have intellectual and cognitive impairments. Working alongside collaborators at the Wolfson Brain Imaging Centre, the project leaders Professor Tony Holland and Dr Shahid Zaman hope that this method of ‘participant information’ will help them recruit the 100 people required to investigate cerebral amyloid development in people with DS.


Almost all people with DS will develop the pathological hallmarks of AD, and up to 50% will develop clinical features of dementia at a much younger age than in the general population. This study, funded by the MRC, will examine the transition between non-disease and disease states with implications for AD, both in the DS and non-DS populations. Cambridge Neuroscientist, Miss Kate McAllister, who features in this short film, has just begun a PhD investigating mitochondrial dysfunction in AD development in DS.

You can take a look at the film on the following link:

Posted on 29/11/2011

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