Dr Philip Buttery We work on the role of rho family GTPases and their regulators in the plasticity of CNS synapses, as related to brain disease and recovery from brain injury. We are currently focussing on a regulator of the GTPase Rac1 which is upregulated with n...
Dr Matthias Landgraf We seek to understand how neural networks are specified and how they assemble during development. The locomotor network of the Drosophila embryo and larva serves as a powerful experimental model. Composed of identified neurons whose connections ha...
Dr Harvey McMahon FRS Molecular mechanisms of vesicle exocytosis, endocytosis and membrane trafficking in neurons.
We are interested in understanding basic mechanisms of vesicle trafficking, especially at the synapse, where synaptic vesicle exocytosis and endocytosis ...
Mr Arkoprovo Paul Arko is studying dendritic spine plasticity in neurons derived from induced pluripotent stem cells (iPSC). In the latter he is modelling synaptic development in the autistic brain, with a particular interest in activity dependent dendritic plastic...
Dr Toshiaki Shigeoka RNA transport and local translation play key roles in the formation and function of neural network. Recent in vitro studies provide evidence that the local translation in axon is critical for the axon pathfinding during development. However, becau...