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• Keyword: stem cells

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• Dr Deep Adhya
  We have recently shown that the in-vitro neural tube structure, the ‘neural rosette’ is affected in autism induced pluripotent stem cell (iPSC) derived neurons. This suggests that an autism diagnosis has genetic and epigenetic influences affecting...
• Professor Andrea Brand FRS FMedSci
  Uncovering the molecular mechanisms that control neural stem quiescence and reactivation is crucial for understanding tissue regeneration under normal and pathological conditions and in response to ageing. It is critical to learn not only how stem...
• Professor Alastair Compston
  My research interests focus on clinical and experimental demyelinating disease with an emphasis on multiple sclerosis - the commonest potentially disabling disease of young adults. The research group has a broad set of interests: we work on the a...
• Professor Anne Ferguson-Smith
  Genomic imprinting is an epigenetic mechanism causing genes to be expressed depending on their parental origin. Our research investigates the mechanism and evolution of genomic imprinting and the function of imprinted genes in development and dise...
• Professor Robin Franklin FMedSci, FRS
  Robin Franklin is a Principal Investigator at Altos Las - Cambridge Institute having previously been Professor of Stem Cell Medicine at the Wellcome Trust-MRC Cambridge Stem Cell Institute. His lab works on the mechanisms of CNS regeneration with ...
• Dr Alexis Joannides
  We have established a scaleable and clinically compatible system for generating and propagating neural stem cells from human embryonic stem (ES) cells. Using this platform, and building on our work on mouse ES cells demonstrating a correlation of ...
• Dr Phil Jones
  We are investigating how normal stem cells transform into cancer cells in a range of sytems, both by studying stem and progenitor cell fate and also by investigating the role of a specific cell fate regulators. Our focus has been on Hes6, which r...
• Miss Çağla Kaya
  For my bachelor's research project at the Duchen Lab at UCL, I used bioinformatics tools to analyse open access RNA sequencing datasets of induced pluripotent stem cells (iPSCs), iPSC-derived astrocytes, and iPSC-derived neural progenitor cells ob...
• Dr Mark Kotter
  My group is interested in the biology of adult CNS stem and precursor cells in the context of disease. A particular focus lies on mechanisms of CNS remyelination, a stem/precursor cell-mediated process in which new myelin sheaths are restored to d...
• Dr Madeline Lancaster
  Human brain development exhibits a number of unique characteristics, such as dramatic size expansion, unique cell types, and distinct neural stem cell behaviors. These characteristics are difficult to examine in model organisms such as mice and ar...
• Professor Keith Martin
  The main goal of our group is to understand better the mechanisms of retinal ganglion cell (RGC) death in glaucoma, the leading cause of irreversible blindness worldwide. We aim to develop methods to protect RGC thus slowing the progression of gla...
• Dr Andrew Osborne
  My research interest lies in how stem cells offer neuroprotection to retinal ganglion cells with particular interest to how secreted factors prevent visual loss. My project focuses on how platelet-derived growth factor (PDGF) can reduce retinal d...
• Dr Rickie Patani
  The focus of my research is neural lineage restriction from human pluripotent stem cells and the subsequent regional fate specification of derived neural precursors. One key area of study is to investigate temporal responsiveness of human neural p...
• Dr Arkoprovo Paul
  I am investigating functional phenotypes of human induced pluripotent stem cell (iPSC) derived Neurons, Astrocytes and Microglia generated using CRISPR/Cas9 genome editing tools and forward reprogramming technologies. My current research is focuss...
• Dr Stefano Pluchino
  Recent evidence from our own laboratory indicates that the systemic injection of somatic neural stem/precursor cells (NPCs) very efficiently protect the CNS from the chronic degeneration induced by inflammation both in small rodents as well as in ...
• Noah Poulin
  I am interested in engineering neural precursor cells to improve the efficacy of cell transplantation in spinal cord injury.
• Miss Amy Rochford
  Peripheral nerve injuries result in a disconnection in the nervous system communication and a consequent loss in neurological function. Currently, there are limited treatments for these conditions. Neuroprosthetics and cell transplantation are pro...
• Professor Ben Simons
  I am interested in applying methods of non-equilibrium statistical mechanics and population dynamics to lineage tracing studies to investigate mechanisms of stem cell fate in development and maintenance. As well as neurogenesis in adult mammalian ...
• Dr Sybil Stacpoole
  I am currently a neurology registrar, having completed a PhD working with neural precursor cells derived from human embryonic stem cells. I studied the pathways involved in directing neural precursor cells into oligodendrocytes, and investigated...
• Dr John Stockley
  I am interested in using in vitro systems to model and understand complex neuron and glial interactions, particularly the interaction between oligodendrocytes, their precursors and neuronal axons for CNS repair as well as understanding memory. I a...
• Stavros Vagionitis MSc, PhD
  Oligodendrocytes produce myelin, a lipoproteinic substance that is wrapped around neuronal axons in a life-long process called myelination. I am studying the contribution of oligodendrocytes and their precursors (OPCs) to myelin maintenance and r...
• Dr Jelle van den Ameele
  I am a neurologist with an interest in developmental neurobiology and mitochondrial genetics. In the lab, we study how cells and tissues respond to mitochondrial dysfunction, focusing on neural stem cells and the brain. Our goal is to identify nov...
• Dr Chao Zhao
  My research focuses on mechanism of remyelination of central nervous system following demyelination in various conditions. After demyelinating injury, the system activates a repair process, which involves oligodendrocyte progenitor cells turning i...

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