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  • Keyword: multiple sclerosis

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  • Professor Alasdair Coles
    We study people with immunological illnesses of the brain, especially multiple sclerosis. Our most important work to date has been on alemtuzumab (Campath-1H), a humanised monoclonal antibody made originally in Cambridge. We started using it to t...
  • Alastair Compston Professor Alastair Compston
    My research interests focus on clinical and experimental demyelinating disease with an emphasis on multiple sclerosis - the commonest potentially disabling disease of young adults. The research group has a broad set of interests: we work on the a...
  • Sarah Foerster
    Oligodendrocytes are the myelinating cells of the central nervous system, functioning to accelerate neurotransmission and provide trophic support to the axon. In response to the pathological loss of oligodendrocytes, myelin sheaths can be replaced...
  • Joanne Jones Dr Joanne Jones
    We study human autoimmunity; in particular we aim to understand why autoimmunity often occurs during recovery from T cell lymphopenia. People with multiple sclerosis, treated with the highly effective lymphocyte depleting antibody alemtuzumab off...
  • Su Metcalfe Dr Su Metcalfe
    The application of nanotechnology to healthcare - nano-medicine - is now recognised worldwide as a new era in clinical medicine. By loading biocompatible, biodegradable nano-particles with growth factor, and targeting to sites of tissue damage, a ...
  • Stephen Sawcer Professor Stephen Sawcer
    My group researches multiple sclerosis. We use genetic analysis to identify relevant variants and then attempt to understand the immunological and neurobiological consequences of these using expression studies and functional assays. As well as con...
  • Dr Sybil Stacpoole
    I am currently a neurology registrar, having completed a PhD working with neural precursor cells derived from human embryonic stem cells. I studied the pathways involved in directing neural precursor cells into oligodendrocytes, and investigated...
  • Chao Zhao Dr Chao Zhao
    My research focuses on mechanism of remyelination of central nervous system following demyelination in various conditions. After demyelinating injury, the system activates a repair process, which involves oligodendrocyte progenitor cells turning i...

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