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• Keyword: mitochondria

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• Professor Guy Brown
  We are interested in the mechanisms of neuroinflammation and neurodegeneration in the brain. We use mouse models of disease and cultured brain cells to investigate how microglia become activated by inflammatory stimuli and how such microglia dama...
• Professor Patrick Chinnery FRCP FMedSci
  I am interested in the genetic basis of neurological disorders, and particularly mitochondrial diseases. Mitochondria are the main source of energy within neurons and glia. Mutations in genes responsible for mitochondrial biogenesis are a major c...
• Dr Victoria Hewitt
  I am investigating how interactions between mitochondria and the endoplasmic reticulum contribute to mitochondrial dynamics in neurons. I am using fruit flies as a model system to determine how perturbing these interactions contributes to neurodeg...
• Dr Janin Lautenschläger
  I am interested in neurodegenerative diseases, in particular on processes at the synapse. A very recent concept in biology is the finding that synaptic proteins can undergo phase separation, forming condensed droplets in another liquid phase (like...
• Andrea Loreto
  Axon degeneration is an early feature of several neurodegenerative diseases, including Parkinson's disease, motor neuron disease, multiple sclerosis and glaucoma. I have recently been awarded a Sir Henry Wellcome postdoctoral fellowship to work i...
• Dr Leonor Miller-Fleming
  My interest is to understand the basic molecular mechanisms that contribute for neurodegenerative diseases. Currently I am focusing on the RNA metabolism dysregulation associated with motor neuron disease and in parallel I am studying the mechanis...
• Dr Luca Peruzzotti-Jametti
  My research focuses on the mechanisms driving chronic CNS damage in conditions of neuroinflammation, such as multiple sclerosis (MS). Currently I am studying how progression works in MS by focusing on the link between immune cell metabolism and ch...
• Dr Katherine Schon BM BCh MRCP
  I am doing clinical and genomic research supervised by Prof Patrick Chinnery and Prof Rita Horvath. I am interested in the use of whole genome sequencing to diagnose mitochondrial disorders. I am working with the 100 000 genomes dataset and with...
• Dr Jelle van den Ameele
  I am a neurologist with an interest in developmental neurobiology and mitochondrial genetics. In the lab, we study how cells and tissues respond to mitochondrial dysfunction, focusing on neural stem cells and the brain. Our goal is to identify nov...
• Dr Alex Whitworth
  My lab is interested in understanding the mechanisms of mitochondrial homeostasis in relation to neurodegenerative diseases such as Parkinson's disease and motor neuron disease. We use a combination of the powerful genetic techniques of Drosophila...
• Dr Patrick Yu-Wai-Man PhD, FRCPath, FRCOphth
  I am an academic neuro-ophthalmologist with a major research interest in mitochondrial eye diseases. My research programme is currently focused on dissecting the molecular genetic basis and the disease mechanisms leading to progressive retinal g...
• Dr Shahid Zaman
  The main theme of our research is to understand the role of amyloid, tau, inflammation and mitochondrial dysfunction in the genesis of cognitive impairment and dementia in people with Down's syndrome.

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