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• Keyword: microscopy

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• Dr Richard Adams
  My group is interested in the mechanisms of morphogenesis that shape the early central nervous system. Using zebrafish as a developmental model, we image the movements of many hundreds of cells using time-lapse micoscopy. Applying methods of image...
• Edward Avezov
  Through an in-depth investigation of the neuronal cell biophysical properties, our program aims to Identify new targetable pathways, disrupted in dementia. In particular, we seek understanding of the role Endoplasmic Reticulum, and its structure f...
• Dorothea Boeken
  I am interested in using single-molecule techniques to study soluble tau aggregates in tauopathy models, such as iPSC-derived neurons and cerebral organoids. These techniques include TIRF microscopy as well as super-resolution microscopy (dSTORM, ...
• Mr Jonathan Breiter
  I focus on the investigation of early-stage aggregates of alpha-synuclein in the human brain, which have been found to be a major contributor to the pathogenesis of Parkinson's Disease and other synucleinopathies. We are working on improving our u...
• Dr Simon Bullock
  Our primary goal is to understand how cellular components are sorted and dispersed by microtubule-based motor complexes, and how these transport processes contribute to the functions of cells in situ (i.e. within organisms). We have long-standing ...
• Professor Albert Cardona
  To study the relationship between circuit structure and function, we must know the synaptic connectivity that defines the circuit structure, observe the activity of the neurons in the circuit over time, study how the pattern of activity can change...
• Dr Andrea Dimitracopoulos
  After training as a Biomedical Engineer at the Sant'Anna School of Advanced Studies in Pisa, Andrea started his PhD in Theoretical Physics and Cell Biology at University College London, on the CoMPLEX programme. Under the supervision of Buzz Baum,...
• Dr Eleni Dimou
  Tau is a soluble protein interacting with tubulin to stabilize microtubules. Under pathological conditions, it becomes hyperphosphorylated and adopts a filamentous conformation with a pivotal role in Alzheimer’s Disease pathogenesis. Although tau ...
• Professor Mike Edwardson
  My research involves imaging of biomolecules using atomic force microscopy (AFM). AFM permits the visualization of single molecules under near-physiological conditions. I am currently studying the effects of activation on the behaviour of ionotrop...
• Dr Alessandro Esposito
  My goal is to understand how cellular biochemistry encodes decision-making processes, particularly those processes that lead to cancer when misregulated. However, the lack of technologies that permit mapping a multitude of biochemical reactions in...
• Mr Emre Fertan
  I have a background in behavioural neuroscience, during which I studied the behavioural and neuropathological changes in mouse models of Alzheimer's disease. My current work focuses on characterising cellular (iPSC and organoid systems), synaptoso...
• Dr Rene Frank
  I am interested in understanding the native molecular architecture of synapses with a particular focus on postsynaptic membranes that contain N-methyl D-aspartic acid receptors (NMDARs). NMDARs mediate Ca2+-dependent signalling, acting in concer...
• Professor Clemens Kaminski
  We develop advanced microscopic imaging techniques that permit us to elucidate molecular mechanisms of neurodegeneration. We use techniques such as lifetime, spectrum and polarisation resolved imaging that inform on protein misfolding, aggregat...
• Dr Gabriele Kaminski Schierle
  Our current research is focused on uncovering the molecular mechanisms that cause proteins to misfold and aggregate in live model systems of Alzheimer’s Disease (AD) and Parkinson’s disease (PD). To enable this work we have developed a range of ad...
• Dr Shekhar Kedia
  The broad aim of my research is to understand the role of inflammation in Neurodegenerative diseases like Alzheimer's disease through state-of-the-art super resolution microscopy techniques
• Dr Janin Lautenschläger
  I am interested in neurodegenerative diseases, in particular on processes at the synapse. A very recent concept in biology is the finding that synaptic proteins can undergo phase separation, forming condensed droplets in another liquid phase (like...
• Miss Kimberly Meechan
  Our group studies neural circuits involved in olfaction in Drosophila. Some neurons involved in these circuits are known to be sexually dimorphic. How these differences lead to different behaviours in male and female flies is not well understood. ...
• Dr Nadine Randel
  Each animal responds to its environment in a dynamic and flexible manner. Behavioral transitions in response to external and internal conditions can be learned or innate actions, mediated by different neuronal circuits throughout the nervous syste...

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