Dr Clemence Blouet Impairments in central pathways regulating energy homeostasis can cause profound metabolic dysfunctions, but current knowledge is insufficient to develop safe and efficient therapies targeting these pathways.
Brain metabolic sensing is based on th...
Miss Sophie Buller Our group studies hypothalamic nutrient sensing and its role in the regulation of energy balance.
Dr Cortina Chen My research has focused on stress as a mechanism for increasing nitric oxide production which has been implicated in the aetiology of stress-related and other neuropathological conditions. I then joined the Neuroinflammation Laboratory at The Univ...
Dr Tony Coll My current research continues to focus upon the roles of the hypothalamus in the control of energy balance. Our current understanding of the central control of appetite has relied heavily upon mouse models and I continue to utilise the power of b...
Professor William Colledge My research group is interested in the neuroendocrine regulation of mammalian fertility using transgenic mice as a model system. Puberty and the regulation of mammalian fertility is controlled by hormonal signalling within the hypothalamus. My re...
Miss Tamana Darwish Feeding behaviour and metabolic state are regulated by many factors- one of the them being nutrient intake. I am interested in how the body responds physiologically the intake of nutrients, in particular to amino acids, which are known to promote ...
Dr Michael Hastings FRS, FMedSci Cellular and molecular basis to circadian rhythms in mammals and its relevance to metabolic and neurological disease.
Professor Allan Herbison We are focused upon understanding the properties and functioning of the key neural populations controlling fertility in mammals; the gonadotropin-releasing hormone (GnRH) neurons and the kisspeptin neurons. Together, these cells generate the “puls...
Ms Sara Kohnke Our group studies the role of protein sensing in the hypothalamus - how it affects body weight and food intake.
Dr Florian Merkle My laboratory uses pluripotent stem cells to model human diseases that arise from the loss of aberrant function of neurons in the hypothalamus that regulate essential physiological and behavioural processes. In particular, obesity is thought to re...
Dr Paul Morris I study the mechanisms of neuronal and network behaviour, focusing on receptors and ion channels.
Following my PhD in NMDA receptor function and regulation in midbrain dopaminergic neurons at Cambridge (under Dr. Sue Jones), I worked at the Unive...
Dr Sofia Papadia I am interested in the neuronal control of obesity, investigating the molecular mechanisms and signalling pathways by which genes in the brain are regulating energy homeostasis.
I have been a member of Prof. I.S. Farooqi's team from 2010-2014 at ...
Dr Sabine Rühle By combining behavioural, genetic, electrophysiological and optical techniques, I aim to investigate how sensory inputs and motivational states are integrated to produce behavioural outputs.
Dr Adam Tozer I am an electrophysiologist working in the Hypothalamus and projecting areas, interested in the neuronal control of diet, and mechanisms controlling food intake and energy balance.
My background is in synaptic physiology and neuronal homeostasis...
Dr Yi-Chun Tung My research interests focus on hypothalamic pathways involved in the regulation of energy homeostasis. During my current post, I am contributing to fundamental systems physiology approaches in rodents. With extensive expertise in hypothalamic neur...
Dr Agatha van der Klaauw I am currently working with Professor Sadaf Farooqi at the Institute of Metabolic Science. We use a number of genetic approaches, including whole-exome sequencing, to identify novel genes involved in hypothalamic development in patients with sever...
Dr Giles Yeo I study brain control of body-weight, and currently have two main aims:
Identifying new players in the hypothalamic control of energy balance.
a. Genetic studies point to the brain as having a crucial role in modulating appetitive behaviour. A col...