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  • Keyword: Protein misfolding

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  • Anne Bertolotti Dr Anne Bertolotti
    Diverse neurodegenerative diseases share a common cause: aggregation of a specific protein in selective regions of the brain. The disease-causing proteins are expressed throughout life but neurodegenerative diseases are mostly late-onset. In fac...
  • Raymond Bujdoso Dr Raymond Bujdoso
    Prion diseases such as scrapie of sheep and goats, BSE of cattle and CJD of humans are transmissible neurodegenerative diseases. The research of our prion group is concerned with providing knowledge to try and answer some of the important question...
  • Michel Goedert Dr Michel Goedert
    Alzheimer's disease and Parkinson's disease are characterized by the presence of abnormal filamentous assemblies within some nerve cells. Similar assemblies are found in related disorders, including progressive supranuclear palsy, dementia with Le...
  • Maya Hanspal Dr Maya Hanspal
    I am interested in the role that protein misfolding plays in neurodegenerative diseases. In recent years, much attention has been drawn to the concept of 'prion-like' aggregation and spatiotemporal spread of misfolding protein in neurodegenerative...
  • Clemens Kaminski Professor Clemens Kaminski
    We develop advanced microscopic imaging techniques that permit us to elucidate molecular mechanisms of neurodegeneration. We use techniques such as lifetime, spectrum and polarisation resolved imaging that inform on protein misfolding, aggregat...
  • Gabriele Kaminski Schierle Dr Gabriele Kaminski Schierle
    Our current research is focused on uncovering the molecular mechanisms that cause proteins to misfold and aggregate in live model systems of Alzheimer’s Disease (AD) and Parkinson’s disease (PD). To enable this work we have developed a range of ad...
  • Alana Thackray Dr Alana Thackray
    Prion diseases, or transmissible spongiform encephalopathies, are infectious, fatal, neurodegenerative conditions of humans and animal species including scrapie in sheep, bovine spongiform encephalopathy in cattle and Creutzfeldt-Jakob disease in ...

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