Profile search results

You searched for profiles matching the following:

  • Keyword: Neurodegeneration

The search produced 34 results.

Search again

  • Dr Gabriel Balmus
    My lab is interested in understanding the roles of DNA Damage Repair (DDR) in mature neurons and its links to neurodegenerative disorders (including Alzheimer's and related diseases) and ageing. We are using a variety of tools including CRISPR-Ca...
  • Dr Gonca Bayraktar
    My research aims to understand how synaptic plasticity governs learning and memory function of the brain and how gradual loss of function or impairment leads to neurodegeneration. treatment of dementia like Alzheimer’s disease. My research focuses...
  • Faye Begeti Dr Faye Begeti
    Problems in cognition are a part of Huntington’s disease (HD) and have a significant impact on quality of life. My main research interest is to investigate the cognitive aspects of HD with the aim of translating animal research into the clinic in...
  • Annabel Curle
    Investigating the role of the DNA damage response in Huntington's Disease.
  • Handan Elaman
    The aim of my research is to further our understanding of the mechanisms underlying age-related axon loss using models of accelerated ageing.
  • Dr Alessandro Esposito
    My goal is to understand how cellular biochemistry encodes decision-making processes, particularly those processes that lead to cancer when misregulated. However, the lack of technologies that permit mapping a multitude of biochemical reactions in...
  • Dr Benjamin Falcon
    Ordered assembly of a small number of proteins into amyloid structures within neurons and, in some cases, glia underlies neurodegenerative disease. We work to understand the molecular basis of amyloid assembly in neurodegenerative disease. Key que...
  • Dr Hugo Fernandes
    I am interested in understanding the molecular mechanisms underlying neuronal cell loss in Parkinson’s and Alzheimer’s diseases. In particular, we are exploring the role of oxidative stress and ER stress in human (iPSC-derived) dopamine neurons us...
  • Éimear Foley
    My research is primarily focused on the role of inflammation in psychiatric disorders. As a research assistant for the Insight study, I am particularly interested in the relationship between the immune system and depression. This research is curre...
  • Oliver Freeman Dr Oliver Freeman
    My research focuses on understanding the mechanisms of neurodegenerative disease. By studying the molecular events leading to neurodegeneration in diseases such as Alzheimer's disease, we aim to develop new targets for treatment.
  • Michel Goedert Dr Michel Goedert
    Alzheimer's disease and Parkinson's disease are characterized by the presence of abnormal filamentous assemblies within some nerve cells. Similar assemblies are found in related disorders, including progressive supranuclear palsy, dementia with Le...
  • Jules Griffin Dr Jules Griffin
    We have been using a range of analytical techniques, and in particular NMR spectroscopy and mass spectrometry, to follow metabolism in the brain in a range of disease processes. This ranges from flux measurements to understand the cycling of metab...
  • Katie Hall Dr Katie Hall PhD
    I am principally interested in the field of behavioural neurosciences with a particular focus in understanding how neurodegenerative pathologies cause dementia symptoms and behavioural dysfunction, as well as developing potential neuroprotective t...
  • Dr Ed Harding
    I am primarily interested in the neuronal control of energy balance and how this is altered in disease. My specific focus is the influence of obesity-associated metabolic syndromes on susceptibility to neurodegenerative diseases.
  • Dr Taxiarchis Katsinelos
    The progressive deposition of misfolded hyperphosphorylated tau is a pathological hallmark and it correlates with the disease progression of tauopathies, such as Alzheimer's disease. My research focuses on employing cellular biology and biochemica...
  • Dr Wei-Li Kuan
    My primary research interest is on investigating novel therapeutics that are potentially disease-modifying in Parkinson's and Huntington's disease. I am also extremely keen in interdisciplinary research and I am currently working with groups of ph...
  • Rick Livesey Dr Rick Livesey
    During embryonic development, all of the neurons in the cerebral cortex, the executive and integrative centre of the mammalian brain, are generated from a complex population of multipotent stem and progenitor cells. We have developed methods for r...
  • Giovanna Mallucci Professor Giovanna Mallucci
    My lab is interested in understanding mechanisms of neurodegeneration. The central theme is the identification of common pathways across the spectrum of these disorders (which include Alzheimer's and related diseases) that are relevant for both me...
  • Nataly Martynyuk Miss Nataly Martynyuk
    The neuron-specific alpha1- and alpha2-chimaerins both contain a C1 domain that recruits chimaerins to DAG-containing membranes, and a GTPase Activating Protein (GAP) domain which acts as a specific inactivator of a Rho family GTPase Rac. Alpha2-c...
  • Dr Emmanouil Metzakopian
    My group is interested in understanding the effect of environmental stress, including oxidative stress, on the progress of neurodegenerative diseases such as Alzheimer's and Parkinson's. Our aim is to identify novel therapeutic targets to protect ...
  • Claire O'Callaghan Dr Claire O'Callaghan
    I am a clinical research fellow with a focus on neuropsychiatric symptoms in neurodegenerative conditions. Symptoms such as apathy, depression, impulsivity and social impairments are common in neurodegenerative disease. My research takes a trans...
  • Cahir O'Kane Dr Cahir O'Kane
    We are interested in the basic biology of axonal ER, and its relevance to neurodegenerative disease, using Drosophila as a model. Axonal ER forms a continuous tubular network throughout the neuron, comparable to a “neuron within a neuron”, potenti...
  • Dr Juan Jose Perez Moreno
    In neurons, endoplasmic reticulum (ER) is not only found in the cell body, but also extends into dendrites and axonal presynaptic terminals. Axonal ER comprises a tubular network of mainly smooth ER, whose function is still poorly understood. In h...
  • Dr Tim Rooney
    I am a research associate at the Alzheimer's Research UK Drug Discovery Institute where I work as a medicinal chemist on a variety of projects related to neurodegeneration. With expertise in drug discovery, organic chemistry and chemical biology, ...
  • Dr Emad Sidhom
    I work as part of Professor Giovanna Mallucci's team that is interested in neurodegenerative disorders. We work to understand the pathological mechanisms underlying neurodegenerative processes. We aim to search for the failure of synaptic repair ...
  • John Skidmore Dr John Skidmore
    I am a medicinal chemist and drug discovery leader interested in working collaboratively with academics and industry in order to translate basic neurodegeneration research into potential new treatments. The Alzheimer’s Research UK Cambridge Drug ...
  • Maria Grazia  Spillantini Professor Maria Grazia Spillantini FRS FMedSci
    Our interest is in the identification of the mechanisms leading to neuronal death and clinical phenotype in diseases such as Alzheimer's disease, Parkinson's disease and frontotemporal dementia. In particular we study the role of microtubule-assoc...
  • Anthony Tsang Dr Anthony Tsang
    Along the major research interest of Dr Blouet's group, my current research focus involves characterising amino acid sensing metabolic neural circuits, both anatomically and functionally. However, during my postgraduate studies, I received solid ...
  • Alessio Vagnoni Dr Alessio Vagnoni
    The main goal of my research is to better understand the mechanisms of neuronal ageing in vivo. I am particularly interested in studying how macromolecules, proteins and organelles are trafficked within neuronal axons and how this process is regul...
  • Romina Vuono Dr Romina Vuono
    My research interests include: 1)Molecular mechanisms involved in the pathogenesis of Huntington's disease 2)Embryonic stem cells as a source for cell therapy in Parkinson's disease 3)Sleep and Circadian rhytm dysruption in Parkinson’s disease
  • Alex Whitworth Dr Alex Whitworth
    My lab is interested in understanding the mechanisms of mitochondrial homeostasis in relation to neurodegenerative diseases such as Parkinson's disease and motor neuron disease. We use a combination of the powerful genetic techniques of Drosophila...
  • Miss Alicia Wilcox
    I have a special interest in neurodegenerative conditions and dementias. These conditions have a similar presentation and many overlapping features, which often implicates diagnosis and treatment. I am looking at how these conditions impact the ...
  • Dr Nigel Wood
    Our research in the Morton lab is focused on understanding the mechanisms underlying neurodegeneration and on developing strategies to delay or prevent the death of neurones in injured or degenerating brain, particularly in Huntington's disease (H...
  • Dr Lidia Wrobel
    I am a post-doctoral researcher at Cambridge Institute for Medical Research. My research interests aim to understand the mechanisms that could prevent accumulation of misfolded toxic proteins in neurodegenerative diseases. To maintain proper prote...

Search again