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  • Keyword: Neurodegeneration

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  • Dr Sanya Aggarwal
    I am primarily interested in the impact of obesity and it's associated metabolic conditions on susceptibility to neurodegenerative diseases and how anti-obesity/ anti-diabetic drugs can confer neuroprotection.
  • Dr Gabriel Balmus
    My lab is interested in understanding the roles of DNA Damage Repair (DDR) in mature neurons and its links to neurodegenerative disorders (including Alzheimer's and related diseases) and ageing. We are using a variety of tools including CRISPR-Ca...
  • Dr Gonca Bayraktar
    My research aims to understand how synaptic plasticity governs learning and memory function of the brain and how gradual loss of function or impairment leads to neurodegeneration. My research focuses on the study of neurodegeneration from various ...
  • Faye Begeti Dr Faye Begeti
    Problems in cognition are a part of Huntington’s disease (HD) and have a significant impact on quality of life. My main research interest is to investigate the cognitive aspects of HD with the aim of translating animal research into the clinic in...
  • Mr Jonathan Breiter
    I focus on the investigation of early-stage aggregates of alpha-synuclein in the human brain, which have been found to be a major contributor to the pathogenesis of Parkinson's Disease and other synucleinopathies. We are working on improving our u...
  • Annabel Curle
    Neuroimmunology in Parkinson's disease
  • Handan Elaman
    The aim of my research is to further our understanding of the mechanisms underlying age-related axon loss using models of accelerated ageing.
  • Dr Alessandro Esposito
    My goal is to understand how cellular biochemistry encodes decision-making processes, particularly those processes that lead to cancer when misregulated. However, the lack of technologies that permit mapping a multitude of biochemical reactions in...
  • Dr Hugo Fernandes
    I am interested in understanding the molecular mechanisms underlying neuronal cell loss in Parkinson’s and Alzheimer’s diseases. In particular, we are exploring the role of oxidative stress and ER stress in human (iPSC-derived) dopamine neurons us...
  • George Gibbons
    I am currently a Research Associate working on developing novel human stem cell derived organoid models to explore disease, injury, and development. Using this platform, I hope to further elucidate novel human specific mechanisms and validate pre...
  • Michel Goedert Dr Michel Goedert
    Alzheimer's disease and Parkinson's disease are characterized by the presence of abnormal filamentous assemblies within some nerve cells. Similar assemblies are found in related disorders, including progressive supranuclear palsy, dementia with Le...
  • Jules Griffin Dr Jules Griffin
    We have been using a range of analytical techniques, and in particular NMR spectroscopy and mass spectrometry, to follow metabolism in the brain in a range of disease processes. This ranges from flux measurements to understand the cycling of metab...
  • Katie Hall Dr Katie Hall PhD
    I am principally interested in the field of behavioural neurosciences with a particular focus in understanding how neurodegenerative pathologies cause dementia symptoms and behavioural dysfunction, as well as developing potential neuroprotective t...
  • Dr Ed Harding
    I am primarily interested in the neuronal control of energy balance and how this is altered in disease. Previously I worked on a specific type of hypothalamic neuron that connects thermoregulatory circuits to the control of NREM sleep initiation. ...
  • Dr Taxiarchis Katsinelos
    The progressive deposition of misfolded hyperphosphorylated tau is a pathological hallmark and it correlates with the disease progression of tauopathies, such as Alzheimer's disease. My research focuses on employing cellular biology and biochemica...
  • Dr Svetlana Khoronenkova
    Human cells repair thousands of DNA lesions daily. The majority of lesions arise from the intrinsic chemical instability of DNA and include single-strand breaks and base modifications. Unrepaired lesions can obstruct DNA replication, leading to mu...
  • Dr Wei-Li Kuan
    My primary research interest is on investigating novel therapeutics that are potentially disease-modifying in Parkinson's and Huntington's disease. I am also extremely keen in interdisciplinary research and I am currently working with groups of ph...
  • Dr Andras Lakatos
    My laboratory develops and uses human organoid and other stem cell-based models to explore mechanisms underlying glia-neuron-synapse interactions in development, injury and neurodegenerative disorders, including ALS and Frontotemporal Dementia. We...
  • Colleen Limegrover
    The aim of my work is to investigate the role of glial cells in traumatic brain injury. Heterogeneity of pathology in patients with TBI creates a complex problem, in terms of modeling the disorder. Secondary injury cascades, including excitotoxici...
  • Giovanna Mallucci Professor Giovanna Mallucci FMedSci
    My lab is interested in understanding mechanisms of neurodegeneration. The central theme is the identification of common pathways across the spectrum of these disorders (which include Alzheimer's and related diseases) that are relevant for both me...
  • Dr Emmanouil Metzakopian
    My group is interested in understanding the effect of environmental stress, including oxidative stress, on the progress of neurodegenerative diseases such as Alzheimer's and Parkinson's. Our aim is to identify novel therapeutic targets to protect ...
  • Dr Stefan Milde
    Cell-based assay development and screening for drug discovery in dementia.
  • Miss Dalila Monica Moisescu
    I am trying to better understand the pathology of neurodegenerative diseases, in order to identify potential treatment targets. I am currently working on a MPhil research project using a nanobody retention system to manipulate the localisation of ...
  • Claire O'Callaghan Dr Claire O'Callaghan
    I am a clinical research fellow with a focus on neuropsychiatric symptoms in neurodegenerative conditions. Symptoms such as apathy, depression, impulsivity and social impairments are common in neurodegenerative disease. My research takes a trans...
  • Cahir O'Kane Dr Cahir O'Kane
    We are interested in the basic biology of axonal ER, and its relevance to neurodegenerative disease, using Drosophila as a model. Axonal ER forms a continuous tubular network throughout the neuron, comparable to a “neuron within a neuron”, potenti...
  • Dr Juan Jose Perez Moreno
    In neurons, endoplasmic reticulum (ER) is not only found in the cell body, but also extends into dendrites and axonal presynaptic terminals. Axonal ER comprises a tubular network of mainly smooth ER, whose function is still poorly understood. In h...
  • Dr Siddharth Ramanan
    I am a neuropsychologist and neuroscientist investigating the genesis and neural contributors of heterogeneous cognitive and behavioural symptoms in neurodegenerative dementia syndromes. I completed my PhD in 2020 from The University of Sydney, Au...
  • Dr Tim Rooney
    I am a research associate at the Alzheimer's Research UK Drug Discovery Institute where I work as a medicinal chemist on a variety of projects related to neurodegeneration. With expertise in drug discovery, organic chemistry and chemical biology, ...
  • Dr Benjamin Ryskeldi-Falcon
    Ordered assembly of a small number of proteins into amyloid structures within neurons and, in some cases, glia underlies neurodegenerative disease. We work to understand the molecular basis of amyloid assembly in neurodegenerative disease. Key que...
  • Dr Kadri Seppa
    Kadri has a keen interest in neurodegeneration induced by the environment. The Sawarkar lab has shown that toxic injury leads to global transcriptional downregulation, and they have generated mouse strains lacking specific domains of proteins that...
  • Dr Emad Sidhom
    I work as part of Professor Giovanna Mallucci's team that is interested in neurodegenerative disorders. We work to understand the pathological mechanisms underlying neurodegenerative processes. We aim to search for the failure of synaptic repair ...
  • John Skidmore Dr John Skidmore
    I am a medicinal chemist and drug discovery leader interested in working collaboratively with academics and industry in order to translate basic neurodegeneration research into potential new treatments. The Alzheimer’s Research UK Cambridge Drug ...
  • Maria Grazia  Spillantini Professor Maria Grazia Spillantini FRS FMedSci
    Our interest is in the identification of the mechanisms leading to neuronal death and clinical phenotype in diseases such as Alzheimer's disease, Parkinson's disease and frontotemporal dementia. In particular we study the role of microtubule-assoc...
  • Anthony Tsang Dr Anthony Tsang
    Along the major research interest of Dr Blouet's group, my current research focus involves characterising amino acid sensing metabolic neural circuits, both anatomically and functionally. However, during my postgraduate studies, I received solid ...
  • Dr Cathryn Ugalde
    Identification of pathways that may be targeted for the therapeutic treatment of neurodegeneration
  • Alessio Vagnoni Dr Alessio Vagnoni
    The main goal of my research is to better understand the mechanisms of neuronal ageing in vivo. I am particularly interested in studying how macromolecules, proteins and organelles are trafficked within neuronal axons and how this process is regul...
  • Alex Whitworth Dr Alex Whitworth
    My lab is interested in understanding the mechanisms of mitochondrial homeostasis in relation to neurodegenerative diseases such as Parkinson's disease and motor neuron disease. We use a combination of the powerful genetic techniques of Drosophila...
  • Miss Alicia Wilcox
    I have a special interest in neurodegenerative conditions and dementias. These conditions have a similar presentation and many overlapping features, which often implicates diagnosis and treatment. I am looking at how these conditions impact the ...
  • Dr Lidia Wrobel
    I am a post-doctoral researcher at Cambridge Institute for Medical Research. My research interests aim to understand the mechanisms that could prevent accumulation of misfolded toxic proteins in neurodegenerative diseases. To maintain proper prote...

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