Professor Guy Brown We are interested in the mechanisms of neuroinflammation and neurodegeneration in the brain. We use mouse models of disease and cultured brain cells to investigate how microglia become activated by inflammatory stimuli and how such microglia dama...
Mr Jacob Dundee My project is to understand the role of microglia in development, tauopathy, and ageing. As a person get older, microglia have been found to ‘eat’ synapses of stressed but still functional neurons, possibly driving the disease progression of many ...
Deniz Ghaffari The chronic presence of cell injury and damage in Alzheimer’s disease (AD) leads to glial activation and increased production of inflammatory cytokines, which in turn lead to further neuronal damage (Morales I. et al., 2014). Recent Genome wide-as...
Dr Antonina Kouli I am a Research Associate interested in neuroinflammation and its role in neurodegenerative diseases. My research focuses on characterizing the inflammatory changes in PD and evaluating their relationship with dementia and other symptoms. This wor...
Dr Luca Peruzzotti-Jametti My research focuses on the mechanisms driving chronic CNS damage in conditions of neuroinflammation, such as multiple sclerosis (MS). Currently I am studying how progression works in MS by focusing on the link between immune cell metabolism and ch...