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  • Keyword: Endoplasmic reticulum

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  • Edward Avezov
    Through an in-depth investigation of the neuronal cell biophysical properties, our program aims to Identify new targetable pathways, disrupted in dementia. In particular, we seek understanding of the role Endoplasmic Reticulum, and its structure f...
  • Victoria Hewitt Dr Victoria Hewitt
    I am investigating how interactions between mitochondria and the endoplasmic reticulum contribute to mitochondrial dynamics in neurons. I am using fruit flies as a model system to determine how perturbing these interactions contributes to neurodeg...
  • Cahir O'Kane Dr Cahir O'Kane
    We are interested in the basic biology of axonal ER, and its relevance to neurodegenerative disease, using Drosophila as a model. Axonal ER forms a continuous tubular network throughout the neuron, comparable to a “neuron within a neuron”, potenti...
  • Dr Megan Oliva
    Axonal endoplasmic reticulum (ER) forms an intracellular tubular network, continuous throughout neurons; its long-range continuity could carry signals independently of action potentials, like a “neuron within a neuron”. An important role for it is...
  • Juan Jose Perez Moreno Dr Juan Jose Perez Moreno
    In neurons, endoplasmic reticulum (ER) is not only found in the cell body, but also extends into dendrites and axonal presynaptic terminals. Axonal ER comprises a tubular network of mainly smooth ER, whose function is still poorly understood. In h...

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