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  • Keyword: Amyloid

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  • Elizabeth English
    My PhD project will analyse Alzheimer’s Disease (AD) brain samples across the disease stages, compared to equivalent healthy brain samples. I will be looking to characterise amyloid-beta, tau, and alpha-synuclein aggregates, in terms of aggregate ...
  • Michel Goedert Dr Michel Goedert
    Alzheimer's disease and Parkinson's disease are characterized by the presence of abnormal filamentous assemblies within some nerve cells. Similar assemblies are found in related disorders, including progressive supranuclear palsy, dementia with Le...
  • Professor David Klenerman
    Small soluble protein aggregates are thought to play a key role in the initial development of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease, but are difficult to study using conventional methods due to their low concent...
  • Dr Janet Kumita
    My research group uses a multidisciplinary approach, including biophysics, cell biology and protein engineering, to study the molecular processes underlying protein self-assembly, in particular aberrant amyloid fibril formation related to disorder...
  • Dr Benjamin Ryskeldi-Falcon
    Ordered assembly of a small number of proteins into amyloid structures within neurons and, in some cases, glia underlies neurodegenerative disease. We work to understand the molecular basis of amyloid assembly in neurodegenerative disease. Key que...
  • Michele Vendruscolo Professor Michele Vendruscolo
    Our research at the Centre for Misfolding Diseases ( is aimed at understanding the molecular origins of neurodegenerative disorders. We have set up an interdisciplinary programme that brings together methods and conc...
  • Dr Shahid Zaman
    The main theme of our research is to understand the role of amyloid, tau, inflammation and mitochondrial dysfunction in the genesis of cognitive impairment and dementia in people with Down's syndrome.

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