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Keyword: Alpha-synuclein

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Dr Michel Goedert
Alzheimer's disease and Parkinson's disease are characterized by the presence of abnormal filamentous assemblies within some nerve cells. Similar assemblies are found in related disorders, including progressive supranuclear palsy, dementia with Le...
Dr Janet Kumita
Protein misfolding is associated with a wide range of human disorders including Alzheimer’s and Parkinson's diseases, systemic amyloidosis and Motor Neurone Disease. Due to the prevalence of these disorders it is crucial to increase our understand...
Dr Janin Lautenschläger
I am interested in neurodegenerative diseases, in particular on processes at the synapse. A very recent concept in biology is the finding that synaptic proteins can undergo phase separation, forming condensed droplets in another liquid phase (like...
Professor Maria Grazia Spillantini FRS FMedSci
Our interest is in the identification of the mechanisms leading to neuronal death and clinical phenotype in diseases such as Alzheimer's disease, Parkinson's disease and frontotemporal dementia. In particular we study the role of microtubule-assoc...