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  • Department: Physiology, Development and Neuroscience

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  • Richard Adams Dr Richard Adams
    My group is interested in the mechanisms of morphogenesis that shape the early central nervous system. Using zebrafish as a developmental model, we image the movements of many hundreds of cells using time-lapse micoscopy. Applying methods of image...
  • Miss Francess Adlard
    My current research interests include understanding the pathogenesis of major neurodegenerative disorders, including Alzheimer's disease and other dementias.
  • Laith Alexander Dr Laith Alexander
    My research focuses on the neurobiology of emotion and emotional regulation. In particular, I am interested in how prefrontal cortical regions (area 25 and 32) subserve the regulation of emotional states. Using sophisticated techniques in behaviou...
  • Dr Xana Almeida
    During neural development the proper number of each specific cell type must be generated at the correct time and place. Thus, a precise balance between cell division, cell survival, cell cycle exit and differentiation must be achieved. However, th...
  • Afnan Azizi
    Light sheet microscopy of whole zebrafish retina to study differentiation dynamics of retinal progenitor cells. Clonal density culture of retinal progenitor cells to investigate factors contributing to cell-autonomous, stochastic differentiation d...
  • Raymundo Baez Mendoza Mr Raymundo Baez Mendoza
    My research interest is in reward neurophysiology.
  • Professor Clare Baker
    We are investigating a broad range of questions relating to the development of neurogenic placodes and the neural crest, two embryonic cell populations in vertebrates that together build the entire peripheral nervous system. Current projects inclu...
  • Dr Riccardo Beltramo
    We aim to understand how the brain transforms sensory signals into the neural representations of the outside world that guide our behaviour. Our lab uses the mouse visual system as a model and studies the contribution of parallel visual pathways ...
  • Sophia Borgeest Gesa Sophia Borgeest
    I'm a PhD student working with Dr Rogier Kievit in the executive processes group at the MRC CBU. I use psychometric techniques in large-sample, multimodal, longitudinal datasets to address how the human brain ages. Specifically, I am investigating...
  • Andrea Brand Professor Andrea Brand FRS FMedSci
    Uncovering the molecular mechanisms that control neural stem quiescence and reactivation is crucial for understanding tissue regeneration under normal and pathological conditions and in response to ageing. It is critical to learn not only how stem...
  • Dennis Bray Dr Dennis Bray
    How do bacteria find distant sources of food, and avoid noxious and potentially damaging environments? We seek answers to these questions by developing computer simulations of swimming bacteria exposed to gradients of different substances. Our pro...
  • Sarah Bray Professor Sarah Bray
    We are interested in understanding the signalling pathways that co-ordinate the decisions made by cells during development. The ultimate fate of a cell is dictated in part by its heredity and in part through interactions with neighbouring cells. O...
  • Dr Clare Buckley
    The vertebrate brain arises from a tube-like structure made from polarised neuroepithelial cells. These have a strict apico-basal orientation; they align their apical ends along a centrally located lumen. This organisation is important for later n...
  • Dr Mark Burrell
    My work seeks to understand what work is worth the work - specifically the biological basis for the reward-effort trade-off in decision-making . I study this on a behavioural level, using economic paradigms, and relate this to individual dopamine ...
  • Mr James Butler
    Recent studies have established dysfunctional evoked and induced gamma (40 Hz) oscillations as well as changes in parvalbumin (PV) interneurons in the brains of schizophrenic patients (Uhlhaas & Singer, 2010). I will express the optogenetic silenc...
  • Emma Cahill Dr Emma Cahill
    My immediate objective is to develop my research in neuronal signalling complexes and apply what I find to unanswered fundamental questions related to memory and adaptive behaviour. In my research, I address the signalling requirements of memories...
  • Professor Albert Cardona
    To study the relationship between circuit structure and function, we must know the synaptic connectivity that defines the circuit structure, observe the activity of the neurons in the circuit over time, study how the pattern of activity can change...
  • Ms Wei-Yan Chow
    Investigating the migration of amacrine cells in the developing zebrafish retina
  • Dr Hannah Clarke
    Understanding the neural and neurochemical basis of behaviours mediated by the prefrontal cortex and their relevance to psychiatric disorders.
  • Mrs Gemma Cockcroft
    Research Assistant in a unit that studies various forms of cognitive and behavioural neuroscience
  • William Colledge Professor William Colledge
    My research group is interested in the neuroendocrine regulation of mammalian fertility using transgenic mice as a model system. Puberty and the regulation of mammalian fertility is controlled by hormonal signalling within the hypothalamus. My re...
  • Geoffrey Cook Dr Geoffrey Cook
    My research concerns the mechanisms controlling axon growth. In the laboratory we are investigating two axon-repulsive systems, 1) the characterization of somite glycoproteins that repel axons, creating the segmented pattern of spinal nerves durin...
  • Andrew Crawford Professor Andrew Crawford
    I am interested in biophysics and physiology of the vertebrate inner ear , especially the cochlea. My research has focussed on the electrophysiology of cochlear hair cells with a view to understanding how they manage to respond to nanometre dis...
  • Julia Dabrowska
    I am a current MPhil student primarily interested in the neurobiology of cognitive processes and behaviours, as well as their clinical effects/applications.
  • Dr Andrea Dimitracopoulos
    After training as a Biomedical Engineer at the Sant'Anna School of Advanced Studies in Pisa, Andrea started his PhD in Theoretical Physics and Cell Biology at University College London, on the CoMPLEX programme. Under the supervision of Buzz Baum,...
  • Alex Dunn
    I'm a PhD student studying the development of cellular-scale brain networks in vitro. I grow primary murine neuronal cultures and record spontaneous activity on microelectrode arrays (MEAs). I also analyse MEA recordings of stem-cell-derived huma...
  • Miss Josefine Eck
    I am currently an MPhil student at the University of Cambridge studying basic and translational neuroscience. I am intrigued by the complexity of neurological dysfunctions and the consequences when individuals lose certain parts of the brain. I am...
  • Steve Edgley Dr Steve Edgley
    I’m interested in how movements are controlled. Our everyday movements are performed with little conscious thought and are remarkably precise. Despite what the textbooks tell you, the way in which this is accomplished is poorly understood. I work ...
  • Dr Andre Ferreira Castro
    So far my research has been driven by a deep fascination for the shape–function relationship in neuroscience. I have been particularly interested in understanding how neuronal structural patterns combined with rich neuronal dynamics provide the b...
  • Kristian Franze
    We are taking an interdisciplinary approach to investigate how cellular forces, local cell and tissue stiffness and cellular mechanosensitivity contribute to CNS development and disease. Methods we are exploiting include atomic force microscopy, t...
  • Dr Tanja Fuchsberger
    The main focus of my research is to investigate mechanisms of synaptic plasticity in health and disease. In my current postdoctoral project, I study molecular mechanisms that affect synaptic changes induced by spike-timing-dependent plasticity in ...
  • Ms Sana Gadiwalla
    Role of Mitf in neuronal plasticity of mitral and tufted cells in the olfactory bulb.
  • Dr Elisa Galliano
    The ability of nerve cells to plastically modify themselves is one of the characteristics that make the brain millions of times more powerful and capable of learning than any supercomputer. I am particularly interested in the ways in which, during...
  • George Gibbons
    I am currently a Research Associate working on developing novel human stem cell derived organoid models to explore disease, injury, and development. Using this platform, I hope to further elucidate novel human specific mechanisms and validate pre...
  • Dino Giussani Professor Dino Giussani
    We have intertwined our interests in oxygen and the development of the central nervous and cardiovascular systems to propose that oxidative stress underlies the common molecular pathway via which prenatal hypoxia contributes to a developmental ori...
  • Fabian Grabenhorst Dr Fabian Grabenhorst
    Our research focuses on the neural mechanisms of reward, decision-making and social cognition. In particular, we study the functions of neurons in the amygdala, a key component of the brain's reward system that is implicated in such diverse condit...
  • Roger Hardie Professor Roger Hardie
    Phototransduction, TRP channels and Calcium signalling in Drosophila Phototransduction in the fruitfly Drosophila is an important model for G-protein coupled signalling and fascinating in its own right. We study the underlying cellular and molecu...
  • Professor William Harris
    Where does the nervous system come from in the embryo? How does it grow to the right size and shape? How do stem cells turn into more committed neuronal progenitors and how do these cells know when to leave the cycle and differentiate into neural ...
  • Professor Allan Herbison
    We are focused upon understanding the properties and functioning of the key neural populations controlling fertility in mammals; the gonadotropin-releasing hormone (GnRH) neurons and the kisspeptin neurons. Together, these cells generate the “puls...
  • Miss Chun Yuan Hii
    Understanding cell polarity in the development of zebrafish neural tube using optogenetics
  • Dr Daniel Hill
    I am interested in the neurophysiology of reward valuation and decision making in the context of learning and memory. My current work is focused on better understanding how dopamine neurons encode value and economic utility. Though their role is w...
  • Christine Holt Professor Christine Holt FMedSci FRS
    My laboratory studies how nerve connections are first established in the brain. We focus on the developing visual system and our main goal is to understand the molecular and cellular mechanisms of axon guidance that enable axons to navigate from t...
  • Fei-Yang HUANG M.D.
    My research focuses on neuroeconomics and decision neurophysiology. We associate neural signals with decision behaviour to elucidate how decisions are made in various context-dependent environment. We design behavioural tasks based on ...
  • Ms Li Huang
    I am researching the ways in which dopaminergic neurons change their form (morphology) and function (firing properties) in order to adapt to the ever-changing environment using the rodent olfactory bulb as my model system. I will be primarily empl...
  • Mr Przemyslaw Jarzebowski
    I look at the development of cortical cultures and use a comparative approach to quantitatively characterise differences in neural activity between healthy and diseased cultures. In my research project I study activity in a culture with a mutation...
  • Susan Jones Dr Susan Jones
    The primary focus of our research is the function of AMPA and NMDA glutamate receptors at excitatory synapses in the brain. We study the properties of glutamate receptors, glutamatergic synaptic transmission, and synaptic plasticity. We are intere...
  • Miss Çağla Kaya
    For my bachelor's research project at the Duchen Lab at UCL, I used bioinformatics tools to analyse open access RNA sequencing datasets of induced pluripotent stem cells (iPSCs), iPSC-derived astrocytes, and iPSC-derived neural progenitor cells ob...
  • Dr David Keays
    The Keays lab exploits cerebral organoids, 2-photon light microscopy, and in vivo genetic methods to investigate important questions in developmental and sensory neurobiology. We are interested in: (1) How mutations in the tubulin and MAST genes c...
  • Nejc Kejzar
    Our lab aims to understand the underlying mechanism of the hippocampal cognitive map through studying interactions of its basic components: place, grid, border and head direction cells. To achieve this, we combine the state of the art experimenta...
  • Roger Keynes Professor Roger Keynes
    Growth cone repulsion is an important mechanism controlling axon growth. During development it guides axons by excluding them from repulsive regions of the embryo. Following injury to the adult brain it may also block axon regeneration, with major...
  • Miss Mona Khodary
    Current masters student on the 2021-22 Basic and Translational Neuroscience Cohort. My interests resolve around cellular and network disfunction in disease, primarly Autism and Alzheimer's disease. For my project I am studying the properties of ne...
  • Mr Marino Krstulovic
    I am working on developing electrophysiological methods in large animal models of Huntington's disease. My primary methods of interest are EEG and Single Cell Recordings.
  • Lilia Kukovska
    My research focuses on understanding the role of cortical inhibition in visual discrimination. I use optogenetics to activate PV+ interneurons in the primary visual cortex and simultaneously record calcium transients using 2-photon imaging to stu...
  • Mr Leonardo Lahijani
    I am interested in pursuing research topics related to animal sentience and the evolution of cognition across species, the effects of mindfulness and meditation of mental health and brain activity, as well as the pharmacological mechanisms of acti...
  • Taylor Lynn-Jones
    My project studies how brain development during adolescence influences motivation in a non-human primate model, the common marmoset. During adolescence, social and cognitive skills, such as learning and memory, continue to develop. This coincides ...
  • Omar Mahroo Dr Omar Mahroo MA, MB, BChir, PhD, FRCOphth, FHEA
    I investigate human retinal function in health and disease, using electrophysiology and complementary approaches including retinal imaging, genetic investigation and machine learning. Key current areas of investigation: -Retinal structure and fu...
  • Matthew Mason Dr Matthew Mason
    I investigate the function and evolution of the middle ear apparatus in vertebrates. Comparative anatomy is backed up with more recent techniques, such as micro-CT and laser interferometry, in order to visualise the middle ear structures and exami...
  • Hugh Matthews Dr Hugh Matthews
    Phototransduction and olfactory transduction. Calcium homeostasis in vertebrate photoreceptors and olfactory receptors, and its role in modulating their electrical responses to stimulation. Light-induced calcium release within the photoreceptor ou...
  • Mollie McKeon
    I am a 1st Year MRes + PhD Student at the Multiple Sclerosis Society Cambridge Centre for Myelin Repair (Wellcome - MRC Cambridge Stem Cell Institute).
  • Ailie McWhinnie
    I am interested in dopamine heterogeneity and will be focussing on the connectivity and physiology of the dopaminergic neurons in the olfactory bulb, with some comparison to those in the midbrain. Using tracing, optogenetics and patch clamp elect...
  • Dr Susanna Mierau
    My research focuses on the fundamental rules that govern the development of synaptic and network activity in the cortex and how this process is disrupted in autism and related disorders, with the ultimate goal of developing novel therapies. I com...
  • Miss Dalila Monica Moisescu
    I am trying to better understand the pathology of neurodegenerative diseases, in order to identify potential treatment targets. I am currently working on a MPhil research project using a nanobody retention system to manipulate the localisation of ...
  • Dr Paul Morris
    My interests lie in the mechanisms underlying neuronal and network function (and dysfunction), focusing on receptors and ion channels. Following my PhD in NMDA receptor function and regulation in midbrain dopaminergic neurons at Cambridge (under ...
  • Miss Emily Mort BSc MRes
    The field of Developmental Origins of Health and Disease has shown that in utero environment can have long lasting consequences for offsrping health. More recent work has shown that maternal obesity can cause changes to the neurodevelopment of off...
  • Professor Jenny Morton
    Our research is focused on understanding the mechanisms underlying neurodegeneration and on developing strategies to delay or prevent the death of neurones in injured or degenerating brain, particularly in Huntington's disease. We are also interes...
  • Dr Kevin Mulvihill
    Current research involved in investigating the prefrontal circuitry associated with negative emotional regulation. Aim is to provide key insights into elements of cognitive and emotional dysregulation potentially involved in neuropsychiatric illne...
  • Miss Ankita Kaur Nagpal
    Implantable neural interfaces offer the potential to gather large amounts of electrophysiological neural recordings. Neuronal firing drives body activity, however, for these recordings to be of use in research, or for the delivery of therapies, th...
  • David Parker Dr David Parker
    We examine cellular and synaptic properties in neuronal networks using the lamprey spinal cord locomotor network as a model system. While this network is claimed, and often cited, as being characterised, there are actually significant gaps in our ...
  • Mr Nicholas Pasternack
    Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder with both motor and cognitive symptoms. At present, no treatments exist to modify the rapidly progressive course of either the motor or cognitive symptoms of the disea...
  • Roy Patterson Dr Roy Patterson
    We have developed a computational model of the auditory signal processing that transforms a sound wave into the auditory image you hear in response to that sound wave. We investigate how the cochlea and neural centres in the auditory pathway proce...
  • Ole Paulsen Professor Ole Paulsen
    The primary interest of my group is the relationship between network oscillations and synaptic plasticity. Network oscillations naturally organise spike timing conducive to spike timing-dependent plasticity (STDP), a strong candidate for a mechani...
  • Miss Sandra Pietsch
    I joined Professor Morton's research group in 2011. Research in the lab aims to understand the mechanisms underlying neurodegeneration and abnormal behaviour in Huntington's disease (HD). I'm focusing on the role of synaptic modulators (specifical...
  • Eva Pillai
    Neurons extend axons across long distances, growing along highly specific 'tracks' to reach their synaptic target in the brain. Most studies of this process have focused on how chemical molecules guide axon navigation accurately. Our lab has shown...
  • Dr Jasper Poort
    I want to understand how we selectively process behaviourally relevant visual input. How does the brain turn a constant overflow of sensory information into selective representations of our environment that can optimally guide our actions? Studyin...
  • Mr Shaun Kit Lung Quah
    Trait anxiety is the enduring disposition of feeling stress, worry, and discomfort and has been proposed to confer an increased vulnerability to developing anxiety disorders. The study of the neural mechanisms underlying trait anxiety is necessary...
  • Dr Eleanor Raffan BVM&S PhD DipECVIM-CA MRCVS
    I am interested in the neural control of energy homeostasis in the body. We study canine models of obesity to discover new genes linked to obesity and interrogate the mechanisms in which genetic variation can influence neural control of metabolis...
  • Dr Mansoor Raza
    Growth cone repulsion during development and adult CNS failure to regenerate after injury. The use of viral vectors for transgene expression in the nervous system to promote axonal regeneration.
  • Angela Roberts Professor Angela Roberts FMedSci
    I am interested in the brain networks underlying cognitive and emotional behaviour. In particular, my research focuses on the executive control functions of the prefrontal cortex and related brain structures, including the basal ganglia and the am...
  • Hugh Robinson Dr Hugh Robinson
    We study synaptic integration in mammalian cortical neurons - encoding of synaptic inputs into patterns of action potentials, or spikes. We are currently interested in - development of advanced electrical stimulation techniques (conductan...
  • John Rogers Dr John Rogers
    Approaches to gene therapy to promote axon regeneration. Specifically: expression of enzymes which can destroy axon-inhibitory proteoglycans, and the use of viral vectors which can express them in injured neurons.
  • Vanessa Roser
  • Andrea Santangelo Dr Andrea Santangelo M
    My work focuses on gene variation associated to emotional and cognitive behaviour. In particular, I study polymorphisms in the serotonin transporter gene that are linked to vulnerability to early-life stress and the development of affective disord...
  • Wolfram Schultz Professor Wolfram Schultz FRS
    Our group is interested to relate the mechanics of brain activity to measurable behaviour. We combine neurophysiological, imaging and behavioural techniques to investigate the neural correlates of goal-directed. We are interested in outcome value ...
  • Christof Schwiening Dr Christof Schwiening
    Electrical activity of neurones is associated with calcium influx through various channels. Most neurones extrude this calcium very rapidly on the plasma-membrane calcium pump (PMCA). Our research shows that this extrusion occurs in exchange for h...
  • Emily Sherman
    I am interested in the differences between learned and innate odour processing in the cortical amygdala and piriform cortex and the subsequent behavioral output. My project aims to elucidate the mechanism behind how animals observe and internalize...
  • Dr Yoshiro Shiba
    I am investigating neural mechanisms underlying anxiety and fear, especially in terms of physiological, behavioural and neurobiological risk factors or traits for development of anxiety disorders.
  • Yoshiro Shiba Yoshiro Shiba
    Anxiety and fear are adaptive responses against a potential/imminent threat. These consist of changes in physiological (heart rate, blood pressure, endocrine responses etc.), cognitive (attention, vigilance etc.) and behavioural (flight, freeze, f...
  • Dr Toshiaki Shigeoka
    RNA transport and local translation play key roles in the formation and function of neural network. Recent in vitro studies provide evidence that the local translation in axon is critical for the axon pathfinding during development. However, becau...
  • Dr William Stauffer
    I am interested in the neuronal computations and value representations underlying economic choice. Dopamine neurons encode reward prediction errors. My current research investigates how this well known teaching signal supports decision making.
  • Imogen Stockwell
  • Roger Thomas Professor Roger Thomas
    Intracellular ion homeostasis in nerve cells. I use pH and Ca2+ sensitive microelectrodes to study ionic interactions inside large snail neurones. I am currently investigating the Ca:H coupling ratio of the plasma membrane Ca pump, or PMCA.
  • David Tolhurst Dr David Tolhurst
    Visual coding of natural scenes. Information coding in the visual cortex studied by single unit recording, computational models and psychophysical discrimination by human observers. Visual deficits in developmental or acquired visual abnormality.
  • Tavish Traut
    PhD student in Dr Fabian Grabenhorst's research group. Our research focuses on the neural mechanisms of reward, decision-making and social cognition.
  • Dr Keira Turner
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  • Vasja Urbančič Vasja Urbančič
    The growth cones of developing axons are guided on their journey through the developing nervous system by guidance cues that instruct their progression along a precise pathway towards their target area. The responses of growth cones to many of the...
  • Ms Vaka Valsdottir
    I am currently working on a project that will use EEG recordings to examine the effect of speaker gaze on infants' statistical language learning.
  • Charlotte van Coeverden Charlotte van Coeverden MSc
    I am interested in how rewards are coded in the brain and how this reflects on social behaviour.
  • Szilvia Vas Dr Szilvia Vas
    My research interest focuses on the regulation of sleep-wake architecture and brain oscillation in different behavioural states. I joined Professor Jenny Morton's research group in 2015 to study the alterations of sleep-wake pattern and EEG spec...
  • Dr Martin Vestergaard
    I investigate theoretical and functional relationships among cognitive and economic constructs of decision psychology and communication. I use psychophysical experimentation, computational models and brain imaging techniques to identify behavioura...
  • Ms Ellen Wall
    The hypothalamus is a structure in the brain which is responsible for the regulation of vital physiological systems, the reproductive system being one of these. It does this by releasing gonadotrophin releasing hormone (GnRH) in a pulsatile manner...
  • Jieni Wang
    Building an automated mouse cage (Autonomouse) for neuroscience experiments.
  • Trevor Wardill Dr Trevor Wardill
    I am a sensory neurobiologist. I investigate evolution of dynamic cephalopod iridescence and colour vision in flies, how they evolved, how they function and what purpose they serve in the ecology of the animal. In particular, I am interested in un...
  • Mr Samuel White
    I am working for a PhD in the Galliano Lab, studying neuronal plasticity in the olfactory bulb. I am using electrophysiology and a range of histological and imaging techniques to study the induced homeostatic changes of plastic cellular and subcel...
  • Dr Ian Winter
    Primitive neural mechanisms of auditory scene analysis. My research searches for neurophysiological correlates of the cues necessary for the segregation and fusion of auditory objects. This work is carried out in close collaboration with psychop...
  • Hovy Wong Dr Hovy Wong
    The role of local translation in axonal branching and synaptogenesis in vivo
  • Dr Christian Wood
    My work focuses on understanding the circuits within the prefrontal cortex that control cognitive and emotional functions, with a view to establishing the dysfunctional pathways that produce symptoms in psychiatric disorders.
  • Dr Peter Wooding
    Correlation between placental structure and function using light and electron microscopy for structure and immunocytochemistry and in situ hybridisation for function. The focus is mainly on ruminants but includes comparative studies on a wide vari...
  • Miss Caroline Wyatt B.A. (Oxon)
    Conducting my MPhil project on developing small antibody (nanobody) modulation of GABA receptors in Dr. Paul Miller's lab. I will continue to work with the lab on a Ph.D. project funded by AstraZeneca in October 2022.
  • Buyun Zhao Buyun Zhao
    The ultimate function of the nervous system is to facilitate survival. To accomplish this task in a dynamically changing environment, the animal's behavioural strategies must alter accordingly given its context. One of the fundamental basis of thi...

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