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• Department: Pharmacology

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• Dr David Bulmer
  Abdominal pain is a leading cause of morbidity in gastrointestinal disease. Despite this we still know little of how pain is triggered in “functional” gastrointestinal disorders such as irritable bowel syndrome (IBS) and gastrointestinal diseases ...
• Ms Sampurna Chakrabarti
  Pain targets in arthritis
• Mr Jasdip Singh Dulai
  My research is orientated towards the more commonly observed nociceptive pain pathway, with a specific interest in inflammation. Using both in silico screening (docking models) and in vitro (electrophysiology) to validate findings. The overall ai...
• Professor Mike Edwardson
  My research involves imaging of biomolecules using atomic force microscopy (AFM). AFM permits the visualization of single molecules under near-physiological conditions. I am currently studying the effects of activation on the behaviour of ionotrop...
• Dr Dervila Glynn
  Following on from a degree in Biotechnology, I completed a PhD in Pharmacology (Downing College) and worked for 11 years in the field of Huntington’s disease (HD). My research focused on understanding the mechanisms underlying neurodegeneration an...
• James Higham
  My PhD with Dr David Bulmer is primarily focussed on investigating interactions between novel inflammatory mediators and nociceptive neurons in culture. I use genetically engineered neurons (in a collaboration with Prof John Wood and Dr James Cox,...
• Mr Ollie King
  Studying novel single-domain antibodies (nanobodies) capable of modulating GABA-A receptors with exquisite subtype selectivity, offering a promising alternative to classical small molecule PAMs like BZD. My research aims to further characterise an...
• Dr Janet Kumita
  Protein misfolding is associated with a wide range of human disorders including Alzheimer’s and Parkinson's diseases, systemic amyloidosis and Motor Neurone Disease. Due to the prevalence of these disorders it is crucial to increase our understand...
• Dr Paul Miller
  I use electrophysiology and structural biology to understand GABA-A receptors and ligands that target them. I am also using these approaches to develop novel small molecule and antibody tools against GABA-A receptor signalling and to study these t...
• Mr Luke Pattison
  My research focuses on the role of proton-sensing G protein-coupled receptors in inflammation.
• Dr Taufiq Rahman
  My research interests broadly lie in two categories - structure-function studies of intracellular calcium channels and rational design and development of selective modulators of signalling proteins including ion channels
• Dr Ewan Smith
  The main interest of the Smith lab is to understand the molecular mechanisms by which sensory neurones detect noxious stimuli, so-called nociceptors. We are particularly interested in how acid activates nociceptors in both physiological and pathop...
• Professor Colin Taylor
  Roles of inositol trisphosphate (IP3) receptors in generating intracellular calcium signals. Structural determinants of IP3 receptor behaviour. Decoding of calcium signals.
• Dr Andrew Thompson
  I am an experienced neuroscientist / pharmacologist with exposure to a broad range of techniques. This has included the development of a simple and information-rich fluorometric microplate assay for simultaneously identifying novel agonists, antag...

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