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  • Department: Biochemistry

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  • Laura Brightman Miss Laura Brightman
    Looking at an In Vitro model of Prader Willi syndrome, a developmental disorder caused by problems (both deletion and epigenetic) with chromosome 15. Modelling cortical development with human patient IPSC lines.
  • Kevin Brindle Professor Kevin Brindle
    We have developed non-invasive magnetic resonance imaging (MRI) techniques that enable us to track labelled cells that have been implanted in the CNS. This work has been conducted in collaboration with Robin Franklin. In addition we are developi...
  • Guy Brown Professor Guy Brown
    We are interested in the mechanisms of neuroinflammation and neurodegeneration in the brain. We use mouse models of disease and cultured brain cells to investigate how microglia become activated by inflammatory stimuli and how such microglia dama...
  • Mr Jacob Dundee
    My project is to understand the role of microglia in development, tauopathy, and ageing. As a person get older, microglia have been found to ‘eat’ synapses of stressed but still functional neurons, possibly driving the disease progression of many ...
  • Jules Griffin Dr Jules Griffin
    We have been using a range of analytical techniques, and in particular NMR spectroscopy and mass spectrometry, to follow metabolism in the brain in a range of disease processes. This ranges from flux measurements to understand the cycling of metab...
  • Tony Jackson Dr Tony Jackson
    In neurones, voltage-gated sodium (Nav) channels initiate the action potential. Sodium channels consist of a ~ 250 kDa alpha-subunit and ~40 kDa beta-subunits. The beta-subunits modulate channel gating. The Nav beta-subunits possess an extracellul...
  • Rick Livesey Dr Rick Livesey
    During embryonic development, all of the neurons in the cerebral cortex, the executive and integrative centre of the mammalian brain, are generated from a complex population of multipotent stem and progenitor cells. We have developed methods for r...
  • Sarah Lummis Professor Sarah Lummis
    My lab works on Cys-loop receptors, which are one of the major classes of ligand-gated ion channels. The family includes in its vertebrate members 5-HT3, nACh, GABAA, GABAC, and glycine receptors. Proteins from this family are critical for fast sy...
  • Dr Federica Marinaro
    Federica Marinaro currently works at the Gurdon Institute, University of Cambridge. Federica does research in Neuroscience. Her current focus is on studying Alzheimer's disease dynamics in human brain.
  • Dr Stefan Milde
    Investigating the role of microglial phagocytic receptors P2Y6R and VNR in inflammatory neuron loss.
  • Dr Kerry Price
    My research involves receptors from the pentameric (Cys-loop) ligand gated ion channel superfamily. A couple of recent advances in the field have given some insight into the structure of related proteins, but the molecular details of the transiti...

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