Dr Timothy Rittman BMBS BMedSci PgCertMedEd MRCP(London) PhD University positionSenior Clinical Research Fellow DepartmentsDepartment of Clinical Neurosciences InstitutesBehavioural and Clinical Neuroscience Institute and Neurology Unit Home pagehttp://www.timrittman.wordpress.com/ (personal home page) Research ThemesInterestsMy main interest is in understanding how neurodegnerative disease progresses through the brain, in particular why neurodegenerative disease affect the brain in predictable patterns. To do this I develop computer models of disease processes using imaging, pathology and genetic data. My clinical interest is in cognitive neurology, particularly Progressive Supranuclear Palsy (PSP) and Corticobasal Degeneration (CBD). These are two rare types of dementia that cause problems with movement and cognition. I have an interest in public engagement with science through the arts as the scientific adviser to the Folkestone Festival of the Brain, and I am an adviser to the Steering Committee for the World Young Leaders in Dementia. Research Focus
EquipmentComputational modelling Electrophysiological recording techniques Magnetic resonance imaging (MRI) Collaborators
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Key publicationsRittman T, Borchert MR, Jones MS, van Swieten J, Borroni B, Galimberti D, Masellis M, Tartaglia MC, Graff C, Tagliavini F, Frisoni GB, Laforce Jr R, Finger E, Mendonça A, Sorbi S, Rohrer JD, Rowe JB (in press), “Functional network resilience to pathology in presymptomatic genetic frontotemporal dementia” Neurobiol Aging Publications2018Cope TE, Rittman T, Borchert RJ, Jones PS, Vatansever D, Allinson K, Passamonti L, Vazquez Rodriguez P, Bevan-Jones WR, O’Brien JT, Rowe JB (2018), “Tau burden and the functional connectome in Alzheimer’s disease and progressive supranuclear palsy” Brain 2015Hughes LE, Rittman T, Regenthal R, Robbins TW, Rowe JB (2015), “Improving response inhibition systems in frontotemporal dementia with citalopram” JNNP 2014Alexander SK, Rittman T, Xuereb JH, Bak TH, Hodges JR, Rowe JB (2014), “Validation of the new consensus criteria for the diagnosis of corticobasal degeneration.” J Neurol Neurosurg Psychiatry 85(8):925-9 Details Nombela C, Rittman T, Robbins TW, Rowe JB (2014), “Multiple modes of impulsivity in Parkinson's disease.” PLoS One 9(1):e85747 Details Wolpe N, Moore JW, Rae CL, Rittman T, Altena E, Haggard P, Rowe JB (2014), “The medial frontal-prefrontal network for altered awareness and control of action in corticobasal syndrome.” Brain 137(Pt 1):208-20 Details Ye Z, Altena E, Nombela C, Housden CR, Maxwell H, Rittman T, Huddleston C, Rae CL, Regenthal R, Sahakian BJ, Barker RA, Robbins TW, Rowe JB (2014), “Improving Response Inhibition in Parkinson's Disease with Atomoxetine.” Biol Psychiatry Details Ye Z, Altena E, Nombela C, Housden CR, Maxwell H, Rittman T, Huddleston C, Rae CL, Regenthal R, Sahakian BJ, Barker RA, Robbins TW, Rowe JB (2014), “Selective serotonin reuptake inhibition modulates response inhibition in Parkinson's disease.” Brain 137(Pt 4):1145-55 Details 2013Rittman T, Ghosh BC, McColgan P, Breen DP, Evans J, Williams-Gray CH, Barker RA, Rowe JB (2013), “The Addenbrooke's Cognitive Examination for the differential diagnosis and longitudinal assessment of patients with parkinsonian disorders.” J Neurol Neurosurg Psychiatry Details 2012Iorio F, Rittman T, Ge H, Menden M, Saez-Rodriguez J (2012), “Transcriptional data: a new gateway to drug repositioning?” Drug Discov Today Details Müller U, Rowe JB, Rittman T, Lewis C, Robbins TW, Sahakian BJ (2012), “Effects of modafinil on non-verbal cognition, task enjoyment and creative thinking in healthy volunteers.” Neuropharmacology Details Rittman T, Corns R, Kumar A, Bhangoo R, Ashkan K (2012), “Is referral to the neuro-oncology MDT safe?” Br J Neurosurg 26(3):321-4 Details Rittman T, Rowe, JB (2012), “What's New in Progressive Supranuclear Palsy?” ACNR 11(6): 8-10 2011Schwarz ST, Rittman T, Gontu V, Morgan PS, Bajaj N, Auer DP (2011), “T1-Weighted MRI shows stage-dependent substantia nigra signal loss in Parkinson's disease.” Mov Disord Details 2010Rio A, Ellis C, Shaw C, Willey E, Ampong MA, Wijesekera L, Rittman T, Nigel Leigh P, Sidhu PS, Al-Chalabi A (2010), “Nutritional factors associated with survival following enteral tube feeding in patients with motor neurone disease.” J Hum Nutr Diet 23(4):408-15 Details 2005Grainge MJ, Seth R, Coupland C, Guo L, Rittman T, Vryenhoef P, Johnson J, Jenkins D, Neal KR (2005), “Human papillomavirus infection in women who develop high-grade cervical intraepithelial neoplasia or cervical cancer: a case-control study in the UK.” Br J Cancer 92(9):1794-9 Details |