Timothy Birkle

Interests

Within the lab of Prof. Guy Brown, I investigate druggable targets within microglial cells which may be useful for tackling neurodegenerative diseases such as Alzheimer's disease. In particular, we are interested in targets which modulate inflammation and phagocytosis, such that inhibiting them might be beneficial in neuroinflammatory conditions. To carry out this research, we mostly use primary cell cultures, automated image analysis, and other functional assays to assess cellular dynamics, morphology, and activity.

Research Focus

Equipment

Behavioural analysis

Cell culture

Confocal microscopy

Flow cytometry

Fluorescence microscopy