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Research Theme Lifelong Brain Development and Brain Ageing Beyond the Neuron Brains and Machines
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Dr Steven Bell

University Position
Senior Research Associate

Interests

I am an Epidemiologist based at the Stroke Research Group with an interest in cardiovascular disease and related conditions. At present my work utilises genome-wide association studies (GWAS) alongside bioinformatic approaches to obtain insights in disease aetiology. This includes applying techniques such as Mendelian randomization to prioritise therapeutic targets and inform clinical or public health decision making. More widely, I have an interest in individual participant data meta-analysis, the use of electronic health records in medical research, the application and integration of various ?-omic? technologies (e.g. metabolomics, proteomics, phenomics), machine learning and modelling of longitudinal data.

Associated News Items

Key Publications

Publications

Predicting incident dementia in cerebral small vessel disease: comparison of machine learning and traditional statistical models.

DOI: http://doi.org/10.1016/j.cccb.2023.100179
Journal: Cereb Circ Cogn Behav
E-pub date: 1 Aug 2023
Authors: R Li, EL Harshfield, S Bell, M Burkhart, AM Tuladhar, S Hilal, DJ Tozer, FM Chappell, SDJ Makin, JW Lo, JM Wardlaw, F-E de Leeuw, C Chen, Z Kourtzi, HS Markus

Association of Vascular Risk Factors and Genetic Factors With Penetrance of Variants Causing Monogenic Stroke.

DOI: http://doi.org/10.1001/jamaneurol.2022.3832
Journal: JAMA Neurol
E-pub date: 1 Dec 2022
Authors: BPH Cho, EL Harshfield, M Al-Thani, DJ Tozer, S Bell, HS Markus

NOTCH3 variants are more common than expected in the general population and associated with stroke and vascular dementia: an analysis of 200 000 participants.

DOI: http://doi.org/10.1136/jnnp-2020-325838
Journal: J Neurol Neurosurg Psychiatry
E-pub date: 1 Jul 2021
Authors: BPH Cho, S Nannoni, EL Harshfield, D Tozer, S Gräf, S Bell, HS Markus

Association Between Depressive Symptoms and Incident Cardiovascular Diseases.

DOI: http://doi.org/10.1001/jama.2020.23068
Journal: JAMA
E-pub date: 15 Dec 2020
Authors: EL Harshfield, L Pennells, JE Schwartz, P Willeit, S Kaptoge, S Bell, JA Shaffer, T Bolton, S Spackman, S Wassertheil-Smoller, F Kee, P Amouyel, SJ Shea, LH Kuller, J Kauhanen, EM van Zutphen, DG Blazer, H Krumholz, PJ Nietert, D Kromhout, G Laughlin, L Berkman, RB Wallace, LA Simons, EM Dennison, ELM Barr, HE Meyer, AM Wood, J Danesh, E Di Angelantonio, KW Davidson, Emerging Risk Factors Collaboration

Is periodontitis a risk factor for ischaemic stroke, coronary artery disease and subclinical atherosclerosis? A Mendelian randomization study.

DOI: http://doi.org/10.1016/j.atherosclerosis.2020.09.029
Journal: Atherosclerosis
E-pub date: 1 Nov 2020
Authors: S Bell, JT Gibson, EL Harshfield, HS Markus