Dr Romina Vuono University positionPostdoc Research Associate DepartmentsDepartment of Clinical Neurosciences InstitutesCambridge Centre for Brain Repair Home pageResearch ThemesInterestsMy research interests include: 1)Molecular mechanisms involved in the pathogenesis of Huntington's disease 2)Embryonic stem cells as a source for cell therapy in Parkinson's disease 3)Sleep and Circadian rhytm dysruption in Parkinson’s disease Research Focus
EquipmentCell culture Computational modelling Confocal microscopy Enzyme assays Fluorescent microscopy FPLC/HPLC Immunohistochemistry Microscopy Protein purification Recombinant protein expression Collaborators
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Publications2013Carri AD, Onorati M, Lelos MJ, Castiglioni V, Faedo A, Menon R, Camnasio S, Vuono R, Spaiardi P, Talpo F, Toselli M, Martino G, Barker RA, Dunnett SB, Biella G, Cattaneo E (2013), “Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32+ medium-sized spiny neurons.” Development 140(2):301-12 Details 2012Ribeiro D, Laguna Goya R, Ravindran G, Vuono R, Parish CL, Foldi C, Piroth T, Yang S, Parmar M, Nikkhah G, Hjerling-Leffler J, Lindvall O, Barker RA, Arenas E (2012), “Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens.” Neurobiol Dis 49C:118-127 Details 2011Anfossi M, Vuono R, Maletta R, Virdee K, Mirabelli M, Colao R, Puccio G, Bernardi L, Frangipane F, Gallo M, Geracitano S, Tomaino C, Curcio SA, Zannino G, Lamenza F, Duyckaerts C, Spillantini MG, Losso MA, Bruni AC (2011), “Compound heterozygosity of 2 novel MAPT mutations in frontotemporal dementia.” Neurobiol Aging 32(4):757.e1-757.e11 Details Spillantini MG, Iovino M, Vuono R (2011), “Release of growth factors by neuronal precursor cells as a treatment for diseases with tau pathology.” Arch Ital Biol 149(2):215-23 Details |