Mr Robert (Bobby) Humphrey

Interests

I study synapse function in neurodegenerative diseases, using organotypic brain slice cultures and electrophysiological recording techniques. In my PhD I hope to establish a relationship between the loss of presynaptic proteins in our slice culture model and functional changes in synaptic activity. Specifically, I am interested in exploring the role of amyloid precursor protein mutations and neuroinflammation in these synapse changes.

Research Focus

Equipment

Confocal microscopy

Electrophysiological recording techniques

Immunohistochemistry

Intracellular recording

qPCR

Westernblotting

Whole cell patch clamp