Neurons are one of the most polarized cells in our body, with their axonal processes sometimes extending distances of more than 1,000-fold the diameter of their cell body. I am interested to study how proteins and organelles are delivered to axons by using live epifluorescence imaging in explanted tibial nerves.
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Associated News Items
Hung CO (2017), “Live-Cell Imaging Reveals Tau Isoforms Imbalance Disrupts Traffic of APP Vesicles in Human Neurons.” J Neurosci.
Hung CO, Coleman MP. (2016), “KIF1A mediates axonal transport of BACE1 and identification of independently moving cargoes in living SCG neurons.” Traffic.