Dr Noham Wolpe

Interests

I am an Academic Clinical Fellow in the Department of Psychiatry.

My broad interest is in the interplay between cognition and action in humans. More specifically, my previous work has been on volition, perception of action and cognitive contributions to motor control, mainly in healthy adults and in older populations, including in patients with neurodegenerative conditions. Currently, I am investigating the mechanism by which deficits in motivation impair the engagement in goal-directed behaviour in patients and in old age. For my research, I use computational neuroscience and neuroimaging methods.

Research Focus

Keywords

Voluntary action

Cognition

Modelling

Neuroimaging

Ageing

Clinical conditions

Alzheimer's disease

Dementia

Schizophrenia

Equipment

Behavioural analysis

Computational modelling

Electroencephalography (EEG)

Magnetic resonance imaging (MRI)

Neuropsychological testing

Collaborators

Cambridge

Paul Fletcher

Rik Henson

James Rowe

Naresh Subramaniam

Kamen Tsvetanov

United Kingdom

Jiaxiang Zhang Web: http://psych.cf.ac.uk/contact...

International

Jason Friedman Web: https://www.curiousjason.com/

James Ingram Web: https://wolpertlab.neuroscience.columbia.edu/people/...

Daniel Wolpert Web: https://wolpertlab.neuroscience.columbia.edu/people/...

Associated News Items


Key publications

Wolpe N, Ingram JN, Tsvetanov KA, Geerligs L, Kievit RA, Henson RN, Wolpert DM, Cam-CAN, Rowe JB (2016), “Ageing increases reliance on sensorimotor prediction through structural and functional differences in frontostriatal circuits” Nature Communications 7

Publications

2018

Wolpe N, Zhang J, Nombela C, Ingram JN, Wolpert DM; Cam-CAN, Rowe JB (2018), “Sensory attenuation in Parkinson's disease is related to disease severity and dopamine dose” Scientific Reports 8(1): 15643

Tsvetanov KA, Ye Z, Hughes L, Samu D, Treder MS, Wolpe N, Tyler LK, Rowe JB, Cambridge Centre for Ageing and Neuroscience (2018), “Activity and Connectivity Differences Underlying Inhibitory Control Across the Adult Life Span” Journal of Neuroscience 38(36): 7887-7900

2016

Zhang J, Nombela C, Wolpe N, Barker RA, Rowe JB (2016), “Time on timing: Dissociating premature responding from interval sensitivity in Parkinson's” Movement Disorders 31(8)

2015

Wolpe N, Nombela C, Rowe JB (2015), “Dopaminergic modulation of positive expectations for goal-directed action: evidence from Parkinson’s disease” Frontiers in psychology 6

2014

Wolpe N, Rowe JB (2014), “Beyond the "urge to move": objective measures for the study of agency in the post-Libet era.” Front Hum Neurosci 8:450 Details

Wolpe N, Wolpert DM, Rowe JB (2014), “Seeing what you want to see: priors for one's own actions represent exaggerated expectations of success.” Front Behav Neurosci 8:232 Details

2013

Wolpe N, Haggard P, Siebner HR, Rowe JB (2013), “Cue integration and the perception of action in intentional binding.” Exp Brain Res Details

Wolpe N, Moore JW, Rae CL, Rittman T, Altena E, Haggard P, Rowe JB (2013), “The medial frontal-prefrontal network for altered awareness and control of action in corticobasal syndrome.” Brain Details

2011

Galli G, Wolpe N, Otten LJ (2011), “Sex differences in the use of anticipatory brain activity to encode emotional events.” J Neurosci 31(34):12364-70 Details