Dr Nicholas MundyUniversity positionReader Dr Nicholas Mundy is pleased to consider applications from prospective PhD students. DepartmentsHome pagehttp://www.zoo.cam.ac.uk/zoostaf... (personal home page) Research ThemesInterestsWe study the evolutionary genetics of brain size and sensory systems in primates. In particular, we are interested in the evolution and selection of colour vision polymorphisms in New World monkeys and lemurs, the evolution of vomeronasal receptor diversity, and the genetics of brain size evolution across primates  A tassel-eared marmoset (Callithrix humeralifer), one of many species of New World monkeys that is polymorphic for colour vision View image full-size (2048x1361 pixels) Research Focus
EquipmentMolecular genetics Collaborators
Associated News ItemsKey publicationsCaine NG, Mundy NI (2000), “Demonstration of a foraging advantage for trichromatic marmosets (Callithrix geoffroyi) dependent on food colour” Proc Roy Soc B 267:439-444 Publications2014Montgomery SH, Mundy NI, Barton RA (2014), “ASPM and mammalian brain evolution: a case study in the difficulty in making macroevolutionary inferences about gene-phenotype associations.” Proc Biol Sci 281(1778):20131743 Details 2013Hohenbrink P, Mundy NI, Zimmermann E, Radespiel U (2013), “First evidence for functional vomeronasal 2 receptor genes in primates.” Biol Lett 9(1):20121006 Details Janssen K, Mundy NI (2013), “Molecular population genetics of the melanic plumage polymorphism in Arctic skuas (Stercorarius parasiticus): evidence for divergent selection on plumage colour.” Mol Ecol 22(18):4634-43 Details Montgomery SH, Mundy NI (2013), “Parallel episodes of phyletic dwarfism in callitrichid and cheirogaleid primates.” J Evol Biol 26(4):810-9 Details Montgomery SH, Mundy NI (2013), “Microcephaly genes and the evolution of sexual dimorphism in primate brain size.” J Evol Biol 26(4):906-11 Details O'Connor TD, Mundy NI (2013), “Evolutionary Modeling of Genotype-Phenotype Associations, and Application to Primate Coding and Non-coding mtDNA Rate Variation.” Evol Bioinform Online 9:301-16 Details 2012Bowden R, MacFie TS, Myers S, Hellenthal G, Nerrienet E, Bontrop RE, Freeman C, Donnelly P, Mundy NI (2012), “Genomic tools for evolution and conservation in the chimpanzee: Pan troglodytes ellioti is a genetically distinct population.” PLoS Genet 8(3):e1002504 Details Hohenbrink P, Radespiel U, Mundy NI (2012), “Pervasive and ongoing positive selection in the vomeronasal-1 receptor (V1R) repertoire of mouse lemurs.” Mol Biol Evol 29(12):3807-16 Details Montgomery SH, Mundy NI (2012), “Positive selection on NIN, a gene involved in neurogenesis, and primate brain evolution.” Genes Brain Behav Details Montgomery SH, Mundy NI (2012), “Evolution of ASPM is associated with both increases and decreases in brain size in primates.” Evolution 66(3):927-32 Details Pointer MA, Kamilar JM, Warmuth V, Chester SG, Delsuc F, Mundy NI, Asher RJ, Bradley BJ (2012), “RUNX2 tandem repeats and the evolution of facial length in placental mammals.” BMC Evol Biol 12:103 Details Pointer MA, Prager M, Andersson S, Mundy NI (2012), “A novel method for screening a vertebrate transcriptome for genes involved in carotenoid binding and metabolism.” Mol Ecol Resour 12(1):149-59 Details Scally A, Dutheil JY, Hillier LW, Jordan GE, Goodhead I, Herrero J, Hobolth A, Lappalainen T, Mailund T, Marques-Bonet T, McCarthy S, Montgomery SH, Schwalie PC, Tang YA, Ward MC, Xue Y, Yngvadottir B, Alkan C, Andersen LN, Ayub Q, Ball EV, Beal K, Bradley BJ, Chen Y, Clee CM, Fitzgerald S, Graves TA, Gu Y, Heath P, Heger A, Karakoc E, Kolb-Kokocinski A, Laird GK, Lunter G, Meader S, Mort M, Mullikin JC, Munch K, O'Connor TD, Phillips AD, Prado-Martinez J, Rogers AS, Sajjadian S, Schmidt D, Shaw K, Simpson JT, Stenson PD, Turner DJ, Vigilant L, Vilella AJ, Whitener W, Zhu B, Cooper DN, de Jong P, Dermitzakis ET, Eichler EE, Flicek P, Goldman N, Mundy NI, Ning Z, Odom DT, Ponting CP, Quail MA, Ryder OA, Searle SM, Warren WC, Wilson RK, Schierup MH, Rogers J, Tyler-Smith C, Durbin R (2012), “Insights into hominid evolution from the gorilla genome sequence.” Nature 483(7388):169-75 Details Walsh N, Dale J, McGraw KJ, Pointer MA, Mundy NI (2012), “Candidate genes for carotenoid coloration in vertebrates and their expression profiles in the carotenoid-containing plumage and bill of a wild bird.” Proc Biol Sci 279(1726):58-66 Details 2011Montgomery SH, Capellini I, Venditti C, Barton RA, Mundy NI (2011), “Adaptive evolution of four microcephaly genes and the evolution of brain size in anthropoid primates.” Mol Biol Evol 28(1):625-38 Details 2010Caine NG, Osorio D, Mundy NI (2010), “A foraging advantage for dichromatic marmosets (Callithrix geoffroyi) at low light intensity.” Biol Lett 6(1):36-8 Details Montgomery SH, Capellini I, Barton RA, Mundy NI (2010), “Reconstructing the ups and downs of primate brain evolution: implications for adaptive hypotheses and Homo floresiensis.” BMC Biol 8:9 Details Montgomery SH, Mundy NI (2010), “Brain evolution: microcephaly genes weigh in.” Curr Biol 20(5):R244-6 Details 2009Bradley BJ, Pedersen A, Mundy NI (2009), “Blue eyes in lemurs and humans: same phenotype, different genetic mechanism.” Am J Phys Anthropol 139(2):269-73 Details Haas F, Pointer MA, Saino N, Brodin A, Mundy NI, Hansson B (2009), “An analysis of population genetic differentiation and genotype-phenotype association across the hybrid zone of carrion and hooded crows using microsatellites and MC1R.” Mol Ecol 18(2):294-305 Details MacFie TS, Nerrienet E, Bontrop RE, Mundy NI (2009), “The action of falciparum malaria on the human and chimpanzee genomes compared: absence of evidence for a genomic signature of malaria at HBB and G6PD in three subspecies of chimpanzee.” Infect Genet Evol 9(6):1248-52 Details MacFie TS, Nerrienet E, de Groot NG, Bontrop RE, Mundy NI (2009), “Patterns of diversity in HIV-related loci among subspecies of chimpanzee: concordance at CCR5 and differences at CXCR4 and CX3CR1.” Mol Biol Evol 26(4):719-27 Details Mundy NI (2009), “Conservation and convergence of colour genetics: MC1R mutations in brown cavefish.” PLoS Genet 5(2):e1000388 Details O'Connor TD, Mundy NI (2009), “Genotype-phenotype associations: substitution models to detect evolutionary associations between phenotypic variables and genotypic evolutionary rate.” Bioinformatics 25(12):i94-100 Details Pastorini J, Zaramody A, Curtis DJ, Nievergelt CM, Mundy NI (2009), “Genetic analysis of hybridization and introgression between wild mongoose and brown lemurs.” BMC Evol Biol 9:32 Details 2008Ishtiaq F, Guillaumot L, Clegg SM, Phillimore AB, Black RA, Owens IP, Mundy NI, Sheldon BC (2008), “Avian haematozoan parasites and their associations with mosquitoes across Southwest Pacific Islands.” Mol Ecol 17(20):4545-55 Details Nadeau NJ, Minvielle F, Ito S, Inoue-Murayama M, Gourichon D, Follett SA, Burke T, Mundy NI (2008), “Characterization of Japanese quail yellow as a genomic deletion upstream of the avian homolog of the mammalian ASIP (agouti) gene.” Genetics 178(2):777-86 Details Pointer MA, Mundy NI (2008), “Testing whether macroevolution follows microevolution: are colour differences among swans (Cygnus) attributable to variation at the MCIR locus?” BMC Evol Biol 8:249 Details Pointer MA, Mundy NI (2008), “Carotenoid genetics: chicken skin sheds light on carotenoid genetics.” Heredity (Edinb) 101(5):393-4 Details 2007Haitina T, Ringholm A, Kelly J, Mundy NI, Schiöth HB (2007), “High diversity in functional properties of melanocortin 1 receptor (MC1R) in divergent primate species is more strongly associated with phylogeny than coat color.” Mol Biol Evol 24(9):2001-8 Details King K, Bagnall R, Fisher SA, Sheikh F, Cuthbert A, Tan S, Mundy NI, Rosenstiel P, Schreiber S, Mathew CG, Roberts RG (2007), “Identification, evolution, and association study of a novel promoter and first exon of the human NOD2 (CARD15) gene.” Genomics 90(4):493-501 Details Mundy NI (2007), “Coloration and the genetics of adaptation.” PLoS Biol 5(9):e250 Details Nadeau NJ, Burke T, Mundy NI (2007), “Evolution of an avian pigmentation gene correlates with a measure of sexual selection.” Proc Biol Sci 274(1620):1807-13 Details Nadeau NJ, Mundy NI, Gourichon D, Minvielle F (2007), “Association of a single-nucleotide substitution in TYRP1 with roux in Japanese quail (Coturnix japonica).” Anim Genet 38(6):609-13 Details 2006Mundy NI (2006), “Genetic basis of olfactory communication in primates.” Am J Primatol 68(6):559-67 Details Mundy NI, Kelly J (2006), “Investigation of the role of the agouti signaling protein gene (ASIP) in coat color evolution in primates.” Mamm Genome 17(12):1205-13 Details Nadeau NJ, Minvielle F, Mundy NI (2006), “Association of a Glu92Lys substitution in MC1R with extended brown in Japanese quail (Coturnix japonica).” Anim Genet 37(3):287-9 Details 2005Mundy NI (2005), “A window on the genetics of evolution: MC1R and plumage colouration in birds.” Proc Biol Sci 272(1573):1633-40 Details Nerrienet E, Santiago ML, Foupouapouognigni Y, Bailes E, Mundy NI, Njinku B, Kfutwah A, Muller-Trutwin MC, Barre-Sinoussi F, Shaw GM, Sharp PM, Hahn BH, Ayouba A (2005), “Simian immunodeficiency virus infection in wild-caught chimpanzees from cameroon.” J Virol 79(2):1312-9 Details Surridge AK, Suárez SS, Buchanan-Smith HM, Mundy NI (2005), “Non-random association of opsin alleles in wild groups of red-bellied tamarins (Saguinus labiatus) and maintenance of the colour vision polymorphism.” Biol Lett 1(4):465-8 Details Surridge AK, Suárez SS, Buchanan-Smith HM, Smith AC, Mundy NI (2005), “Color vision pigment frequencies in wild tamarins (Saguinus spp.).” Am J Primatol 67(4):463-70 Details 2004Eggert LS, Mundy NI, Woodruff DS (2004), “Population structure of loggerhead shrikes in the California Channel Islands.” Mol Ecol 13(8):2121-33 Details Filip LC, Mundy NI (2004), “Rapid evolution by positive Darwinian selection in the extracellular domain of the abundant lymphocyte protein CD45 in primates.” Mol Biol Evol 21(8):1504-11 Details Mundy NI, Badcock NS, Hart T, Scribner K, Janssen K, Nadeau NJ (2004), “Conserved genetic basis of a quantitative plumage trait involved in mate choice.” Science 303(5665):1870-3 Details Mundy NI, Helbig AJ (2004), “Origin and evolution of tandem repeats in the mitochondrial DNA control region of shrikes (Lanius spp.).” J Mol Evol 59(2):250-7 Details 2003Ling MK, Lagerström MC, Fredriksson R, Okimoto R, Mundy NI, Takeuchi S, Schiöth HB (2003), “Association of feather colour with constitutively active melanocortin 1 receptors in chicken.” Eur J Biochem 270(7):1441-9 Details Majerus ME, Mundy NI (2003), “Mammalian melanism: natural selection in black and white.” Trends Genet 19(11):585-8 Details Mundy NI, Cook S (2003), “Positive selection during the diversification of class I vomeronasal receptor-like (V1RL) genes, putative pheromone receptor genes, in human and primate evolution.” Mol Biol Evol 20(11):1805-10 Details Mundy NI, Kelly J (2003), “Evolution of a pigmentation gene, the melanocortin-1 receptor, in primates.” Am J Phys Anthropol 121(1):67-80 Details Mundy NI, Kelly J, Theron E, Hawkins K (2003), “Evolutionary genetics of the melanocortin-1 receptor in vertebrates.” Ann N Y Acad Sci 994:307-12 Details Smith AC, Buchanan-Smith HM, Surridge AK, Mundy NI (2003), “Leaders of progressions in wild mixed-species troops of saddleback (Saguinus fuscicollis) and mustached tamarins (S. mystax), with emphasis on color vision and sex.” Am J Primatol 61(4):145-57 Details Smith AC, Buchanan-Smith HM, Surridge AK, Osorio D, Mundy NI (2003), “The effect of colour vision status on the detection and selection of fruits by tamarins (Saguinus spp.).” J Exp Biol 206(Pt 18):3159-65 Details Whinnett A, Mundy NI (2003), “Isolation of novel olfactory receptor genes in marmosets (Callithrix): insights into pseudogene formation and evidence for functional degeneracy in non-human primates.” Gene 304:87-96 Details |
