Maura Malpetti University positionRace Against Dementia & Alzheimer's Research UK Fellow Maura Malpetti is pleased to consider applications from prospective PhD students. DepartmentsDepartment of Clinical Neurosciences InstitutesHome pagehttps://ftd.neurology.cam.ac.uk/ Research ThemesInterestsI am a Race Against Dementia & ARUK fellow at the Cambridge Centre for Frontotemporal Dementia and Related disorders. I am interested in the study of neuropathology, biomarkers and clinical features of neurodegenerative diseases, with special interest in frontotemporal lobar degeneration (FTLD) and Alzheimer's disease (AD). My work focuses on the application of neuroimaging techniques (multi-tracer PET and MRI) to investigate the pathophysiology of neurodegenerative diseases, in order to identify early diagnostic and prognostic markers. As a RAD fellow, I am studying novel clinically viable PET and other biomarkers for inflammation, tau and synaptic loss in FTLD. To this end, I apply longitudinal statistical models and multimodal imaging analyses, with an interdisciplinary approach that integrates imaging and clinical data with fluid markers and post-mortem pathology. Research Focus
EquipmentMagnetic resonance imaging (MRI) Neuropsychological testing Positron Emission Tomography (PET) Collaborators
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Key publicationsMalpetti M, Kievit RA, Passamonti L, Jones PS, Tsvetanov KA, Rittman T, Mak E, Nicastro N, Bevan-Jones WR, Su L, Hong YT, Fryer TD, Aigbirhio FI, O'Brien JT, Rowe JB (2020), “Microglial activation and tau burden predict cognitive decline in Alzheimer's disease” Brain 143(5):1588-1602 |