Dr Michael Lombardo University positionHonorary Senior Researcher DepartmentsInstitutesHome pagehttp://sites.google.com/site/mv... (personal home page) Research ThemesInterestsI am interested in understanding the mechanisms occurring in early development that are behind atypical brain development in autism and other neurodevelopmental disorders.  Early autism language subgroups differentiate in neural response to speech View image full-size (2081x2343 pixels) Research Focus
EquipmentBehavioural analysis Computational modelling Magnetic resonance imaging (MRI) Neuropsychological testing Collaborators
Associated News ItemsKey publicationsBaron-Cohen S, Auyeung B, Nørgaard-Pedersen B, Hougaard DM, Abdallah MW, Melgaard L, Cohen AS, Chakrabarti B, Ruta L, Lombardo MV (2015), “Elevated fetal steroidogenic activity in autism.” Mol Psychiatry 20(3):369-76 PDF Details Lombardo MV, Pierce K, Eyler LT, Carter Barnes C, Ahrens-Barbeau C, Solso S, Campbell K, Courchesne E (2015), “Different Functional Neural Substrates for Good and Poor Language Outcome in Autism.” Neuron Details Pramparo T, Pierce K, Lombardo MV, Carter Barnes C, Marinero S, Ahrens-Barbeau C, Murray SS, Lopez L, Xu R, Courchesne E (2015), “Prediction of autism by translation and immune/inflammation coexpressed genes in toddlers from pediatric community practices.” JAMA Psychiatry 72(4):386-94 Details Lai MC, Lombardo MV, Baron-Cohen S (2014), “Autism.” Lancet 383(9920):896-910 Details Auyeung B, Lombardo MV, Baron-Cohen S (2013), “Prenatal and postnatal hormone effects on the human brain and cognition.” Pflugers Arch 465(5):557-71 Details Lai MC, Lombardo MV, Chakrabarti B, Baron-Cohen S (2013), “Subgrouping the autism "spectrum": reflections on DSM-5.” PLoS Biol 11(4):e1001544 PDF Details Lai MC, Lombardo MV, Suckling J, Ruigrok AN, Chakrabarti B, Ecker C, Deoni SC, Craig MC, Murphy DG, Bullmore ET, MRC AIMS Consortium, Baron-Cohen S (2013), “Biological sex affects the neurobiology of autism.” Brain 136(Pt 9):2799-815 Details Lombardo MV, Ashwin E, Auyeung B, Chakrabarti B, Lai MC, Taylor K, Hackett G, Bullmore ET, Baron-Cohen S (2012), “Fetal Programming Effects of Testosterone on the Reward System and Behavioral Approach Tendencies in Humans.” Biol Psychiatry Details Lombardo MV, Ashwin E, Auyeung B, Chakrabarti B, Taylor K, Hackett G, Bullmore ET, Baron-Cohen S (2012), “Fetal Testosterone Influences Sexually Dimorphic Gray Matter in the Human Brain.” J Neurosci 32(2):674-680 PDF Details Lombardo MV, Chakrabarti B, Lai MC, MRC AIMS Consortium, Baron-Cohen S (2012), “Self-referential and social cognition in a case of autism and agenesis of the corpus callosum.” Mol Autism 3(1):14 PDF Details Baron-Cohen S, Lombardo MV, Auyeung B, Ashwin E, Chakrabarti B, Knickmeyer R (2011), “Why are autism spectrum conditions more prevalent in males?” PLoS Biol 9(6):e1001081 PDF Details Lombardo MV, Baron-Cohen S (2011), “The role of the self in mindblindness in autism.” Conscious Cogn 20(1):130-40 Details Lombardo MV, Baron-Cohen S, Belmonte MK, Chakrabarti B (2011), “Neural endophenotypes of social behaviour in autism spectrum conditions” Oxford Handbook of Social Neuroscience Lombardo MV, Chakrabarti B, Bullmore ET, Baron-Cohen S, MRC AIMS Consortium (2011), “Specialization of right temporo-parietal junction for mentalizing and its relation to social impairments in autism.” Neuroimage 56(3):1832-8 Details Chura LR, Lombardo MV, Ashwin E, Auyeung B, Chakrabarti B, Bullmore ET, Baron-Cohen S (2010), “Organizational effects of fetal testosterone on human corpus callosum size and asymmetry.” Psychoneuroendocrinology 35(1):122-32 Details Lombardo MV, Baron-Cohen S (2010), “Unraveling the paradox of the autistic self” WIREs Cogn Sci 1(3): 393-403 Lombardo MV, Chakrabarti B, Bullmore ET, Sadek SA, Pasco G, Wheelwright SJ, Suckling J, MRC AIMS Consortium, Baron-Cohen S (2010), “Atypical neural self-representation in autism.” Brain 133(Pt 2):611-24 Details Lombardo MV, Chakrabarti B, Bullmore ET, Wheelwright SJ, Sadek SA, Suckling J, MRC AIMS Consortium, Baron-Cohen S (2010), “Shared neural circuits for mentalizing about the self and others.” J Cogn Neurosci 22(7):1623-35 Details Lombardo MV, Barnes JL, Wheelwright SJ, & Baron-Cohen S (2007), “Self-referential cognition and empathy in autism” PLoS One 2:e883 PDF Details Publications2015Auyeung B, Lombardo MV, Heinrichs M, Chakrabarti B, Sule A, Deakin JB, Bethlehem RA, Dickens L, Mooney N, Sipple JA, Thiemann P, Baron-Cohen S (2015), “Oxytocin increases eye contact during a real-time, naturalistic social interaction in males with and without autism.” Transl Psychiatry 5:e507 PDF Details Balardin JB, Sato JR, Vieira G, Feng Y, Daly E, Murphy C, MRC AIMS Consortium, Murphy D, Ecker C (2015), “Relationship Between Surface-Based Brain Morphometric Measures and Intelligence in Autism Spectrum Disorders: Influence of History of Language Delay.” Autism Res Details Cadman T, Spain D, Johnston P, Russell A, Mataix-Cols D, Craig M, Deeley Q, Robertson D, Murphy C, Gillan N, Wilson CE, Mendez M, Ecker C, Daly E, Findon J, Glaser K, MRC AIMS Consortium, Happé F, Murphy D (2015), “Obsessive-Compulsive Disorder in Adults with High-Functioning Autism Spectrum Disorder: What Does Self-Report with the OCI-R Tell Us?” Autism Res Details Deoni SC, Zinkstok JR, Daly E, Ecker C, MRC AIMS Consortium, Williams SC, Murphy DG (2015), “White-matter relaxation time and myelin water fraction differences in young adults with autism.” Psychol Med 45(4):795-805 Details Fanti KA, Panayiotou G, Lombardo MV, Kyranides MN (2015), “Unemotional on all counts: Evidence of reduced affective responses in individuals with high callous-unemotional traits across emotion systems and valences.” Soc Neurosci Details Lai MC, Lombardo MV, Auyeung B, Chakrabarti B, Baron-Cohen S (2015), “Sex/gender differences and autism: setting the scene for future research.” J Am Acad Child Adolesc Psychiatry 54(1):11-24 PDF Details Moseley RL, Shtyrov Y, Mohr B, Lombardo MV, Baron-Cohen S, Pulvermüller F (2015), “Lost for emotion words: what motor and limbic brain activity reveals about autism and semantic theory.” Neuroimage 104:413-22 Details 2014Chantiluke K, Christakou A, Murphy CM, Giampietro V, Daly EM, Ecker C, Brammer M, Murphy DG, the MRC AIMS Consortium, Rubia K (2014), “Disorder-specific functional abnormalities during temporal discounting in youth with Attention Deficit Hyperactivity Disorder (ADHD), Autism and comorbid ADHD and Autism.” Psychiatry Res Details Lai MC, Lombardo MV, Ecker C, Chakrabarti B, Suckling J, Bullmore ET, Happé F, MRC AIMS Consortium, Murphy DG, Baron-Cohen S (2014), “Neuroanatomy of Individual Differences in Language in Adult Males with Autism.” Cereb Cortex PDF Details Moseley RL, Pulvermüller F, Mohr B, Lombardo MV, Baron-Cohen S, Shtyrov Y (2014), “Brain routes for reading in adults with and without autism: EMEG evidence.” J Autism Dev Disord 44(1):137-53 Details Murphy CM, Christakou A, Daly EM, Ecker C, Giampietro V, Brammer M, Smith AB, Johnston P, Robertson DM, MRC AIMS Consortium, Murphy DG, Rubia K (2014), “Abnormal Functional Activation and Maturation of Fronto-Striato-Temporal and Cerebellar Regions During Sustained Attention in Autism Spectrum Disorder.” Am J Psychiatry Details Ruigrok AN, Salimi-Khorshidi G, Lai MC, Baron-Cohen S, Lombardo MV, Tait RJ, Suckling J (2014), “A meta-analysis of sex differences in human brain structure.” Neurosci Biobehav Rev 39:34-50 Details Suckling J, Henty J, Ecker C, Deoni SC, Lombardo MV, Baron-Cohen S, Jezzard P, Barnes A, Chakrabarti B, Ooi C, Lai MC, Williams SC, Murphy DG, Bullmore E, for the MRC AIMS Consortium (2014), “Are power calculations useful? A multicentre neuroimaging study.” Hum Brain Mapp Details Walsh ND, Dalgleish T, Lombardo MV, Dunn VJ, Van Harmelen AL, Ban M, Goodyer IM (2014), “General and specific effects of early-life psychosocial adversities on adolescent grey matter volume.” Neuroimage Clin 4:308-18 PDF Details Wilson CE, Happé F, Wheelwright SJ, Ecker C, Lombardo MV, Johnston P, Daly E, Murphy CM, Spain D, Lai MC, Chakrabarti B, Sauter DA, MRC AIMS Consortium, Baron-Cohen S, Murphy DG (2014), “The Neuropsychology of Male Adults With High-Functioning Autism or Asperger Syndrome.” Autism Res Details 2013Christakou A, Murphy CM, Chantiluke K, Cubillo AI, Smith AB, Giampietro V, Daly E, Ecker C, Robertson D, MRC AIMS consortium, Murphy DG, Rubia K (2013), “Disorder-specific functional abnormalities during sustained attention in youth with Attention Deficit Hyperactivity Disorder (ADHD) and with autism.” Mol Psychiatry 18(2):236-44 Details Ecker C, Ginestet C, Feng Y, Johnston P, Lombardo MV, Lai MC, Suckling J, Palaniyappan L, Daly E, Murphy CM, Williams SC, Bullmore ET, Baron-Cohen S, Brammer M, Murphy DG, MRC AIMS Consortium (2013), “Brain surface anatomy in adults with autism: the relationship between surface area, cortical thickness, and autistic symptoms.” JAMA Psychiatry 70(1):59-70 Details Ecker C, Ronan L, Feng Y, Daly E, Murphy C, Ginestet CE, Brammer M, Fletcher PC, Bullmore ET, Suckling J, Baron-Cohen S, Williams S, Loth E, MRC AIMS Consortium, Murphy DG (2013), “Intrinsic gray-matter connectivity of the brain in adults with autism spectrum disorder.” Proc Natl Acad Sci U S A 110(32):13222-7 Details Moseley RL, Mohr B, Lombardo MV, Baron-Cohen S, Hauk O, Pulvermüller F (2013), “Brain and behavioral correlates of action semantic deficits in autism.” Front Hum Neurosci 7:725 Details Sato JR, Hoexter MQ, Oliveira PP Jr, Brammer MJ, MRC AIMS Consortium, Murphy D, Ecker C (2013), “Inter-regional cortical thickness correlations are associated with autistic symptoms: a machine-learning approach.” J Psychiatr Res 47(4):453-9 Details 2012Beacher FD, Minati L, Baron-Cohen S, Lombardo MV, Lai MC, Gray MA, Harrison NA, Critchley HD (2012), “Autism attenuates sex differences in brain structure: a combined voxel-based morphometry and diffusion tensor imaging study.” AJNR Am J Neuroradiol 33(1):83-9 Details Beacher FD, Radulescu E, Minati L, Baron-Cohen S, Lombardo MV, Lai MC, Walker A, Howard D, Gray MA, Harrison NA, Critchley HD (2012), “Sex Differences and Autism: Brain Function during Verbal Fluency and Mental Rotation.” PLoS One 7(6):e38355 Details Ecker C, Suckling J, Deoni SC, Lombardo MV, Bullmore ET, Baron-Cohen S, Catani M, Jezzard P, Barnes A, Bailey AJ, Williams SC, Murphy DG, for the MRC AIMS Consortium (2012), “Brain Anatomy and Its Relationship to Behavior in Adults With Autism Spectrum Disorder: A Multicenter Magnetic Resonance Imaging Study.” Arch Gen Psychiatry 69(2):195-209 Details Lai MC, Lombardo MV, Chakrabarti B, Ecker C, Sadek SA, Wheelwright SJ, Murphy DG, Suckling J, Bullmore ET, MRC AIMS Consortium, Baron-Cohen S (2012), “Individual differences in brain structure underpin empathizing-systemizing cognitive styles in male adults.” Neuroimage Details Lai MC, Lombardo MV, Ruigrok AN, Chakrabarti B, Wheelwright SJ, Auyeung B, Allison C, MRC AIMS Consortium, Baron-Cohen S (2012), “Cognition in males and females with autism: similarities and differences.” PLoS One 7(10):e47198 PDF Details Langen M, Leemans A, Johnston P, Ecker C, Daly E, Murphy CM, Dell'acqua F, Durston S, the AIMS Consortium, Murphy DG (2012), “Fronto-striatal circuitry and inhibitory control in autism: Findings from diffusion tensor imaging tractography.” Cortex 48(2):183-193 Details Sundram F, Deeley Q, Sarkar S, Daly E, Latham R, Craig M, Raczek M, Fahy T, Picchioni M, UK AIMS Network, Barker GJ, Murphy DG (2012), “White matter microstructural abnormalities in the frontal lobe of adults with antisocial personality disorder.” Cortex 48(2):216-29 Details 2011Lai MC, Lombardo MV, Pasco G, Ruigrok AN, Wheelwright SJ, Sadek SA, Chakrabarti B, MRC AIMS Consortium, Baron-Cohen S (2011), “A behavioral comparison of male and female adults with high functioning autism spectrum conditions.” PLoS One 6(6):e20835 PDF Details 2010Beer JS, Lombardo MV, Bhanji JP (2010), “Roles of Medial Prefrontal Cortex and Orbitofrontal Cortex in Self-evaluation.” J Cogn Neurosci 22(9):2108-19 Details Ecker C, Rocha-Rego V, Johnston P, Mourao-Miranda J, Marquand A, Daly EM, Brammer MJ, Murphy C, Murphy DG, MRC AIMS Consortium (2010), “Investigating the predictive value of whole-brain structural MR scans in autism: a pattern classification approach.” Neuroimage 49(1):44-56 Details Lai MC, Lombardo MV, Chakrabarti B, Sadek SA, Pasco G, Wheelwright SJ, Bullmore ET, Baron-Cohen S, MRC AIMS Consortium, Suckling J (2010), “A Shift to Randomness of Brain Oscillations in People with Autism.” Biol Psychiatry Details 2009Barnes JL, Lombardo MV, Wheelwright S, Baron-Cohen S (2009), “Moral Dilemmas Film Task: a study of spontaneous narratives by individuals with autism spectrum conditions.” Autism Res Details Lombardo MV, Chakrabarti B, Baron-Cohen S (2009), “The amygdala in autism: not adapting to faces?” Am J Psychiatry 166(4):395-7 Details Lombardo MV, Chakrabarti B, Baron-Cohen S (2009), “What neuroimaging and perceptions of self-other similarity can tell us about the mechanism underlying mentalizing.” Behav Brain Sci 32(2):152-153 Minio-Paluello I, Lombardo MV, Chakrabarti B, Wheelwright S, Baron-Cohen S (2009), “Response to Smith's Letter to the Editor 'Emotional Empathy in Autism Spectrum Conditions: Weak, Intact, or Heightened?'” J Autism Dev Disord 2008Beer JS, Stallen M, Lombardo MV, Gonsalkorale K, Cunningham WA, Sherman JW (2008), “The Quadruple Process model approach to examining the neural underpinnings of prejudice.” Neuroimage 43(4):775-83 Details Cohen MX, Lombardo MV, Blumenfeld RS (2008), “Covariance-based subdivision of the human striatum using T1-weighted MRI.” Eur J Neurosci 27(6):1534-46 Details |
