Mr Michael Hart University positionPhD student DepartmentsDepartment of Clinical Neurosciences and Department of Psychiatry InstitutesNeurosurgery Unit, Wolfson Brain Imaging Centre, Behavioural and Clinical Neuroscience Institute and Brain Mapping Unit Home pagehttp://www.mrmikehart.com (personal home page) Research ThemesInterestsResolving the dichotomy between effective resection of focal lesions and preservation of brain function is a fundamental goal in neurosurgery. To achieve this, I have started a PhD on brain mapping under the supervision of Professor John Suckling. Resting state functional MRI allows identification of complex brain networks. Graph theoretical analysis allows characterisation of core features in these networks including how they respond to attack and disruption. Developing models of fully connected and weighted networks is key to understanding how the brain responds to focal lesions. Studying normal brain network development during adolescence will allow identification of principles that determine network formation and that ultimately may guide their reconstruction.
 Functional connectome in a patient with a brain tumour Click image to view full-size Research Focus
EquipmentComputational modelling diffusion tensor imaging Electrophysiological recording techniques Field potential recording graph theoretical analysis of complex networks Magnetic resonance imaging (MRI) Neuropsychological testing resting state functional MRI Collaborators
Associated News Items
Key publicationsHart MG, Ypma R-J, Romero-Garcia R, Price SJ, Suckling J (2015), “Graph theory analysis of complex brain networks: new concepts in brain mapping applied to neurosurgery” Journal of Neurosurgery PDF Publications2014Barone DG, Lawrie TA, Hart MG (2014), “Image guided surgery for the resection of brain tumours.” Cochrane Database Syst Rev 1:CD009685 Details Hart MG, Czosnyka M, Czosnyka ZH, Fernandes HM (2014), “Combined Intracranial Pressure Monitoring and Cerebrospinal Fluid Infusion Study to Guide Management of Slit Ventricle Syndrome.” Pediatr Neurosurg Details 2013Hart MG, Garside R, Rogers G, Stein K, Grant R (2013), “Temozolomide for high grade glioma.” Cochrane Database Syst Rev 4:CD007415 Details Hart MG, Santarius T, Kirollos RW (2013), “How I do it--pineal surgery: supracerebellar infratentorial versus occipital transtentorial.” Acta Neurochir (Wien) 155(3):463-7 Details Hart MG, Santarius T, Trivedi RA (2013), “Muscle and nerve biopsy for the neurosurgical trainee.” Br J Neurosurg 27(6):727-34 Details Hart MG, Sarkies NJ, Santarius T, Kirollos RW (2013), “Ophthalmological outcome after resection of tumors based on the pineal gland.” J Neurosurg 119(2):420-6 Details 2012Hart MG, Grant R (2012), “Brain Tumours” Evidence Based Neurology Hart MG, Nowell M, Coakham HB (2012), “Radiofrequency thermocoagulation for trigeminal neuralgia without intra-operative patient waking.” Br J Neurosurg 26(3):392-6 Details Hart MG, Trivedi RA, Hutchinson PJ (2012), “Boxing sparring complicated by an acute subdural haematoma and brainstem haemorrhage.” Br J Neurosurg 26(5):776-8 Details Hart MG, Whittle IR, Grant R (2012), “Steroids and brain tumors.” Handb Clin Neurol 104:371-9 Details 2011Erridge SC, Hart MG, Kerr GR, Smith C, McNamara S, Grant R, Gregor A, Whittle IR (2011), “Trends in classification, referral and treatment and the effect on outcome of patients with glioma: a 20 year cohort.” J Neurooncol 104(3):789-800 Details Hart MG (2011), “External ventricular drain insertion” Core Surgery Journal 2(1):50-55 Hart MG (2011), “Hydrocephalus” Core Surgery Journal 1(6):54-61 Hart MG, Grant R, Garside R, Rogers G, Somerville M, Stein K (2011), “Chemotherapy wafers for high grade glioma.” Cochrane Database Syst Rev (3):CD007294 Details Hart MG, Trivedi RA (2011), “Spinal cord trauma” Core Surgery Journal 1(3):42-49 2007Connor S, Hart MG, Redhead DN, Ireland H, Madhavan KK, Parks RW, Garden OJ (2007), “Follow-up and outcomes for resection of colorectal liver metastases in Edinburgh.” Eur J Surg Oncol 33(1):55-60 Details 2005Hart MG, Grant R, Walker M, Dickinson H (2005), “Surgical resection and whole brain radiation therapy versus whole brain radiation therapy alone for single brain metastases.” Cochrane Database Syst Rev (1):CD003292 Details Hart MG, Hooper G (2005), “Clinical associations of Dupuytren's disease.” Postgrad Med J 81(957):425-8 Details 2000Hart MG, Grant R, Metcalfe SE. (2000), “Biopsy or resection for High Grade Glioma. ” Cochrane Database of Systematic Reviews. |