Dr Menghon Cheah


My research focuses on investigating the extracellular and intracellular mechanisms for axon regeneration in the central nervous system after injury. In addition to a plethora of inhibitory factors present in the injured microenviroment, the absence of growth promoting factors and the neurons themselves lacking the regenerative potential are all possible contributing factors. By understanding how neurons respond to injury and the corresponding cellular mechanisms, one can hopefully develop a treatment for spinal cord injury.

DRG sensory neurons
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Research Focus


spinal cord injury

axon regeneration



gene therapy

Clinical conditions

Movement disorders

Spinal cord injury


Behavioural analysis

Cell culture

Electrophysiological recording techniques

Fluorescence microscopy



Recombinant protein expression


No collaborators listed

Associated News Items

    Key publications

    Cheah M, Andrews MR, Chew DJ, Moloney EB, Verhaagen J, Fässler R, Fawcett JW (2016), “Expression of an Activated Integrin Promotes Long-Distance Sensory Axon Regeneration in the Spinal Cord” J Neurosci 36(27):7283-97



    Cheah M, Fawcett JW, Andrews MR (2017), “Dorsal Root Ganglion Injection and Dorsal Root Crush Injury as a Model for Sensory Axon Regeneration” J Vis Exp 123

    Cheah M, Fawcett JW, Haenzi B (2017), “Differential regenerative ability of sensory and motor neurons” Neurosci Lett 652:35-40


    Andrews MR, Soleman S, Cheah M, Tumbarello DA, Mason MR, Moloney E, Verhaagen J, Bensadoun JC, Schneider B, Aebischer P, Fawcett JW (2016), “Axonal Localization of Integrins in the CNS Is Neuronal Type and Age Dependent” eNeuro 3(4)

    Cheah M, Andrews MR (2016), “Targeting cell surface receptors for axon regeneration in the central nervous system” Neural Regen Res 11(12):1884-1887


    Kappagantula S, Andrews MR, Cheah M, Abad-Rodriguez J, Dotti CG, Fawcett JW (2014), “Neu3 sialidase-mediated ganglioside conversion is necessary for axon regeneration and is blocked in CNS axons.” J Neurosci 34(7):2477-92 Details