Dr Maxime Bertoux CPsychol

Maxime Bertoux

University position

Marie Sklodowska-Curie Fellow


Department of Clinical Neurosciences


Neurology Unit



Home page


Research Theme

Cognitive and Behavioural Neuroscience


At the interaction between cognitive neurosciences and clinical neuropsychology, my aim is to develop novel procedure of assessment, diagnosis and follow-up for neurodegenerative diseases such as Frontotemporal Dementia or Alzheimer's disease.

In contrasting these conditions as two different prototypes of brain atrophy and cognitive/behavioural impairment, I intend to participate to the characterisation of high level cognitive functions such as decision making or social cognition related processes.

Research Focus



Social cognition


Frontotemporal dementia

Alzheimer's disease

Clinical conditions

Alzheimer's disease


Depressive disorders

Frontotemporal Dementia


Behavioural analysis

Magnetic resonance imaging (MRI)

Neuropsychological testing

Positron Emission Tomography (PET)



Michael Hornberger

Claire O'Callaghan


Sacha Bourgeois-Gironde

Leonardo C. de Souza

Bruno Dubois

Marie Sarazin

Associated News Items



    Hamelin L*, Bertoux M*, Bottlaender M, Corne H, Lagarde J, Hahn V, Mangin JF, Dubois B, Chupin M, de Souza LC, Colliot O, Sarazin M. (2016), “Sulcal morphology as a new imaging marker for the diagnosis of early onset Alzheimer's disease” Neurobiology of Aging


    Bertoux M, de Souza LC, O'Callaghan C, Greve A, Sarazin M, Dubois B, Hornberger M (2015), “Social Cognition Deficits: The Key to Discriminate Behavioral Variant Frontotemporal Dementia from Alzheimer’s Disease Regardless of Amnesia?” J Alz Dis

    Bertoux M, de Souza LC, Sarazin M, Funkiewiez A, Dubois B, Hornberger M (2015), “How Preserved is Emotion Recognition in Alzheimer Disease Compared With Behavioral Variant Frontotemporal Dementia?” Alzheimer Dis Assoc Disord 29(2):154-7 Details

    Bertoux M, de Souza LC, Zamith P, Dubois B, Bourgeois-Gironde S (2015), “Discounting of Future Rewards in Behavioural Variant Frontotemporal Dementia & Alzheimer's Disease.” Neuropsychology Details

    Bertoux M, Hornberger M (2015), “'Try to see it my way': which theory of mind tests best distinguish bvFTD and AD?” J Neurol Neurosurg Psychiatry 86(7):706 Details

    Bertoux M, O'Callaghan C, Dubois B, Hornberger M (2015), “In two minds: executive functioning versus theory of mind in behavioural variant frontotemporal dementia.” J Neurol Neurosurg Psychiatry

    Bertoux M, O'Callaghan C, Flanagan E, Hodges, JR, Hornberger M (2015), “Fronto-striatal atrophy in behavioral variant frontotemporal dementia and Alzheimer’s disease” Frontiers in Neurology 6(147)

    Hornberger M, Bertoux M (2015), “Right lateral prefrontal cortex-specificity for inhibition or strategy use?” Brain 138(Pt 4):833-5 Details

    Hornberger M, Bertoux M (2015), “Reply: Strategy and suppression impairments after right lateral and orbito-frontal lesions.” Brain

    O'Callaghan C, Bertoux M, Irish M, Shine JM, Wong S, Spiliopoulos L, Hodges JR, Hornberger M (2015), “Fair play: social norm compliance failures in behavioural variant frontotemporal dementia.” Brain


    Bertoux M, Cova F, Pessiglione M, Hsu M, Dubois B, Bourgeois-Gironde S (2014), “Behavioral variant frontotemporal dementia patients do not succumb to the Allais paradox.” Front Neurosci 8:287 Details

    Bertoux M, de Souza LC, Corlier F, Lamari F, Bottlaender M, Dubois B, Sarazin M (2014), “Two distinct amnesic profiles in behavioral variant frontotemporal dementia.” Biol Psychiatry 75(7):582-8 Details

    Bertoux M, Volle E, de Souza LC, Funkiewiez A, Dubois B, Habert MO (2014), “Neural correlates of the mini-SEA (Social cognition and Emotional Assessment) in behavioral variant frontotemporal dementia.” Brain Imaging Behav 8(1):1-6 Details

    O'Callaghan C, Bertoux M, Hornberger M (2014), “Beyond and below the cortex: the contribution of striatal dysfunction to cognition and behaviour in neurodegeneration.” J Neurol Neurosurg Psychiatry 85(4):371-8 Details


    Bertoux M, Funkiewiez A, O'Callaghan C, Dubois B, Hornberger M (2013), “Sensitivity and specificity of ventromedial prefrontal cortex tests in behavioral variant frontotemporal dementia.” Alzheimers Dement 9(5 Suppl):S84-94 Details

    De Souza LC, Bertoux M, Funkiewiez A, Samri D, Azuar C, Habert MO, Kas A, Lamari F, Sarazin M, Dubois B (2013), “Frontal presentation of Alzheimer's disease A series of patients with biological evidence by CSF biomarkers” Dement Neuropsychol. 7:66-74.

    de Souza LC, Chupin M, Bertoux M, Lehéricy S, Dubois B, Lamari F, Le Ber I, Bottlaender M, Colliot O, Sarazin M (2013), “Is hippocampal volume a good marker to differentiate Alzheimer's disease from frontotemporal dementia?” J Alzheimers Dis 36(1):57-66 Details

    Kloeters S, Bertoux M, O'Callaghan C, Hodges JR, Hornberger M (2013), “Money for nothing - Atrophy correlates of gambling decision making in behavioural variant frontotemporal dementia and Alzheimer's disease.” Neuroimage Clin 2:263-72 Details

    Lebreton M, Bertoux M, Boutet C, Lehericy S, Dubois B, Fossati P, Pessiglione M (2013), “A critical role for the hippocampus in the valuation of imagined outcomes.” PLoS Biol 11(10):e1001684 Details

    Nguyen T, Bertoux B, O'Callaghan C, Ahmed S, R. Hodges J, Hornberger M (2013), “Grey and white matter brain network changes in frontotemporal dementia subtypes ” Translational Neuroscience. 4(4):410.

    O'Callaghan C, Naismith SL, Shine JM, Bertoux M, Lewis SJ, Hornberger M (2013), “A novel bedside task to tap inhibitory dysfunction and fronto-striatal atrophy in Parkinson's disease.” Parkinsonism Relat Disord 19(9):827-30 Details


    Bertoux M, Delavest M, de Souza LC, Funkiewiez A, Lépine JP, Fossati P, Dubois B, Sarazin M (2012), “Social Cognition and Emotional Assessment differentiates frontotemporal dementia from depression.” J Neurol Neurosurg Psychiatry 83(4):411-6 Details

    Bertoux M, Volle E, Funkiewiez A, de Souza LC, Leclercq D, Dubois B (2012), “Social Cognition and Emotional Assessment (SEA) is a marker of medial and orbital frontal functions: a voxel-based morphometry study in behavioral variant of frontotemporal degeneration.” J Int Neuropsychol Soc 18(6):972-85 Details

    Cova F, Bertoux M, Bourgeois-Gironde S, Dubois B (2012), “Judgments about moral responsibility and determinism in patients with behavioural variant of frontotemporal dementia: still compatibilists.” Conscious Cogn 21(2):851-64 Details

    Funkiewiez A, Bertoux M, de Souza LC, Lévy R, Dubois B (2012), “The SEA (Social cognition and Emotional Assessment): a clinical neuropsychological tool for early diagnosis of frontal variant of frontotemporal lobar degeneration.” Neuropsychology 26(1):81-90 Details

    Sarazin M, Dubois B, de Souza LC, Bertoux M (2012), “Should the Social Cognition and Emotional Assessment replace standard neuropsychological tests for frontotemporal dementia?” Expert Rev Neurother 12(6):633-5 Details

    Vorspan F, Bertoux M, Brichant-Petitjean C, Dubois B, Lépine JP (2012), “Relapsing-remitting behavioural variant of frontotemporal dementia in a bipolar patient.” Funct Neurol 27(3):193-6 Details


    Allali G, Dubois B, Assal F, Lallart E, de Souza LC, Bertoux M, Annweiler C, Herrmann FR, Levy R, Beauchet O (2010), “Frontotemporal dementia: pathology of gait?” Mov Disord 25(6):731-7 Details

    de Souza LC, Volle E, Bertoux M, Czernecki V, Funkiewiez A, Allali G, Leroy B, Sarazin M, Habert MO, Dubois B, Kas A, Levy R (2010), “Poor creativity in frontotemporal dementia: a window into the neural bases of the creative mind.” Neuropsychologia 48(13):3733-42 Details


    Rozencwajg P, Bertoux M (2008), “Categorization and Aging as measured by an adapted version of Wechsler’s similarities test” Current Psychology Letters: Behaviour, Brain and Cognition Vol. 24, 2