Marco Tripodi University positionGroup Leader Marco Tripodi is pleased to consider applications from prospective PhD students. InstitutesMedical Research Council Laboratory of Molecular Biology Home pagehttp://tripodilab.com (personal home page) Research ThemesInterestsOne of the major tasks that the nervous system faces is that of linking perception to action. We perceive the world around us through our senses and we use this information to select the most appropriate set of actions. My lab studies the organization and function of neural circuits controlling movement in mice. Our aim is to define the neural circuits responsible for generating automatic and goal-oriented movements and delineate the underlying sensory-motor integration processes that link perception to action. We investigate these questions by using and developing a variety of methodologies. These include mouse genetics, viral strategies for circuit tracing and functional manipulation, in vivo electrophysiology, optogenetics and behavioral analysis. Research Focus
EquipmentBehavioural analysis Calcium imaging Cell culture Confocal microscopy Electrophysiological recording techniques Field potential recording Fluorescence microscopy Immunohistochemistry Intracellular recording Microscopy Whole cell patch clamp Collaborators
Associated News Items
Publications2014Kohl J, Ng J, Cachero S, Ciabatti E, Dolan MJ, Sutcliffe B, Tozer A, Ruehle S, Krueger D, Frechter S, Branco T, Tripodi M, Jefferis GS (2014), “Ultrafast tissue staining with chemical tags.” Proc Natl Acad Sci U S A 111(36):E3805-14 Details 2012Tripodi M, Arber S (2012), “Regulation of motor circuit assembly by spatial and temporal mechanisms.” Curr Opin Neurobiol 22(4):615-23 Details 2011Tripodi M, Stepien AE, Arber S (2011), “Motor antagonism exposed by spatial segregation and timing of neurogenesis.” Nature 479(7371):61-6 Details 2010Stepien AE, Tripodi M, Arber S (2010), “Monosynaptic rabies virus reveals premotor network organization and synaptic specificity of cholinergic partition cells.” Neuron 68(3):456-72 Details 2009Mauss A, Tripodi M, Evers JF, Landgraf M (2009), “Midline signalling systems direct the formation of a neural map by dendritic targeting in the Drosophila motor system.” PLoS Biol 7(9):e1000200 Details 2008Tripodi M, Evers JF, Mauss A, Bate M, Landgraf M (2008), “Structural homeostasis: compensatory adjustments of dendritic arbor geometry in response to variations of synaptic input.” PLoS Biol 6(10):e260 Details 2004Tripodi M, Filosa A, Armentano M, Studer M (2004), “The COUP-TF nuclear receptors regulate cell migration in the mammalian basal forebrain.” Development 131(24):6119-29 Details |