Marco Tripodi is pleased to consider applications from prospective PhD students.
Medical Research Council Laboratory of Molecular Biology
http://tripodilab.com (personal home page)
Systems and Computational Neuroscience
One of the major tasks that the nervous system faces is that of linking perception to action. We perceive the world around us through our senses and we use this information to select the most appropriate set of actions.
My lab studies the organization and function of neural circuits controlling movement in mice. Our aim is to define the neural circuits responsible for generating automatic and goal-oriented movements and delineate the underlying sensory-motor integration processes that link perception to action. We investigate these questions by using and developing a variety of methodologies. These include mouse genetics, viral strategies for circuit tracing and functional manipulation, in vivo electrophysiology, optogenetics and behavioral analysis.
Electrophysiological recording techniques
Field potential recording
Whole cell patch clamp
Associated News Items
Kohl J, Ng J, Cachero S, Ciabatti E, Dolan MJ, Sutcliffe B, Tozer A, Ruehle S, Krueger D, Frechter S, Branco T, Tripodi M, Jefferis GS (2014), “Ultrafast tissue staining with chemical tags.” Proc Natl Acad Sci U S A 111(36):E3805-14 Details
Tripodi M, Arber S (2012), “Regulation of motor circuit assembly by spatial and temporal mechanisms.” Curr Opin Neurobiol 22(4):615-23 Details
Tripodi M, Stepien AE, Arber S (2011), “Motor antagonism exposed by spatial segregation and timing of neurogenesis.” Nature 479(7371):61-6 Details
Stepien AE, Tripodi M, Arber S (2010), “Monosynaptic rabies virus reveals premotor network organization and synaptic specificity of cholinergic partition cells.” Neuron 68(3):456-72 Details
Mauss A, Tripodi M, Evers JF, Landgraf M (2009), “Midline signalling systems direct the formation of a neural map by dendritic targeting in the Drosophila motor system.” PLoS Biol 7(9):e1000200 Details
Tripodi M, Evers JF, Mauss A, Bate M, Landgraf M (2008), “Structural homeostasis: compensatory adjustments of dendritic arbor geometry in response to variations of synaptic input.” PLoS Biol 6(10):e260 Details
Tripodi M, Filosa A, Armentano M, Studer M (2004), “The COUP-TF nuclear receptors regulate cell migration in the mammalian basal forebrain.” Development 131(24):6119-29 Details