Dr Lisa Saksida![]() University positionReader Dr Lisa Saksida is pleased to consider applications from prospective PhD students. DepartmentsInstitutesBehavioural and Clinical Neuroscience Institute Home pagehttp://www.tcnlab.psychol.cam.ac.uk (personal home page) Research ThemesInterestsWe are working toward a better understanding of the psychological processes underlying memory and perception through a programme of theoretically-driven experimental research using both healthy subjects and brain-damaged populations. Research in my lab spans across several species (from mouse to human) and techniques (lesion studies, pharmacology, computational modelling, genetically modified mouse models, patient studies), in each case using the appropriate species and technique for the specific question at hand. ![]() A connectionist model of the development of object representations in the temporal lobe with visual experience. Click image to view full-size Research Focus
EquipmentBehavioural analysis Computational modelling Genetically modified animal models Pharmacological manipulations Temporary and permanent brain lesions Collaborators
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Key publicationsCowell RA, Bussey TJ, Saksida LM (2010), “Functional dissociations within the ventral object processing pathway: cognitive modules or a hierarchical continuum?” J Cogn Neurosci 22(11):2460-79 Details McTighe SM, Cowell RA, Winters BD, Bussey TJ, Saksida LM (2010), “Paradoxical false memory for objects after brain damage.” Science 330(6009):1408-10 Details Cowell RC, Bussey TJ, Saksida LM (2006), “Why does brain damage impair memory? A connectionist model of object recognition memory in perirhinal cortex” Journal of Neuroscience 26:12186-97 Publications2015Brigman JL, Daut RA, Saksida L, Bussey TJ, Nakazawa K, Holmes A (2015), “Impaired discrimination learning in interneuronal NMDAR-GluN2B mutant mice.” Neuroreport 26(9):489-94 Details Kent BA, Beynon AL, Hornsby AK, Bekinschtein P, Bussey TJ, Davies JS, Saksida LM (2015), “The orexigenic hormone acyl-ghrelin increases adult hippocampal neurogenesis and enhances pattern separation.” Psychoneuroendocrinology 51:431-9 Details Kim CH, Heath CJ, Kent BA, Bussey TJ, Saksida LM (2015), “The role of the dorsal hippocampus in two versions of the touchscreen automated paired associates learning (PAL) task for mice.” Psychopharmacology (Berl) Details Menzies FM, Garcia-Arencibia M, Imarisio S, O'Sullivan NC, Ricketts T, Kent BA, Rao MV, Lam W, Green-Thompson ZW, Nixon RA, Saksida LM, Bussey TJ, O'Kane CJ, Rubinsztein DC (2015), “Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity.” Cell Death Differ 22(3):433-44 Details Yang S, Cacquevel M, Saksida LM, Bussey TJ, Schneider BL, Aebischer P, Melani R, Pizzorusso T, Fawcett JW, Spillantini MG (2015), “Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology.” Exp Neurol 265:48-58 Details 2014Bartko SJ, Winters BD, Saksida LM, Bussey TJ (2014), “Different Roles for M1 and M2 Receptors Within Perirhinal Cortex in Object Recognition and Discrimination.” Neurobiol Learn Mem Details Bekinschtein P, Kent BA, Oomen CA, Clemenson GD, Gage FH, Saksida LM, Bussey TJ (2014), “Brain-derived neurotrophic factor interacts with adult-born immature cells in the dentate gyrus during consolidation of overlapping memories.” Hippocampus 24(8):905-11 Details Graybeal C, Bachu M, Mozhui K, Saksida LM, Bussey TJ, Sagalyn E, Williams RW, Holmes A (2014), “Strains and stressors: an analysis of touchscreen learning in genetically diverse mouse strains.” PLoS One 9(2):e87745 Details 2013Bekinschtein P, Kent BA, Oomen CA, Clemenson GD, Gage FH, Saksida LM, Bussey TJ (2013), “BDNF in the dentate gyrus is required for consolidation of "pattern-separated" memories.” Cell Rep 5(3):759-68 Details Brigman JL, Daut RA, Wright T, Gunduz-Cinar O, Graybeal C, Davis MI, Jiang Z, Saksida LM, Jinde S, Pease M, Bussey TJ, Lovinger DM, Nakazawa K, Holmes A (2013), “GluN2B in corticostriatal circuits governs choice learning and choice shifting.” Nat Neurosci 16(8):1101-10 Details DePoy L, Daut R, Brigman JL, MacPherson K, Crowley N, Gunduz-Cinar O, Pickens CL, Cinar R, Saksida LM, Kunos G, Lovinger DM, Bussey TJ, Camp MC, Holmes A (2013), “Chronic alcohol produces neuroadaptations to prime dorsal striatal learning.” Proc Natl Acad Sci U S A 110(36):14783-8 Details Horner AE, Heath CJ, Hvoslef-Eide M, Kent BA, Kim CH, Nilsson SR, Alsiö J, Oomen CA, Holmes A, Saksida LM, Bussey TJ (2013), “The touchscreen operant platform for testing learning and memory in rats and mice.” Nat Protoc 8(10):1961-84 Details Mar AC, Horner AE, Nilsson SR, Alsiö J, Kent BA, Kim CH, Holmes A, Saksida LM, Bussey TJ (2013), “The touchscreen operant platform for assessing executive function in rats and mice.” Nat Protoc 8(10):1985-2005 Details McAllister KA, Saksida LM, Bussey TJ (2013), “Dissociation between memory retention across a delay and pattern separation following medial prefrontal cortex lesions in the touchscreen TUNL task.” Neurobiol Learn Mem 101C:120-126 Details Nithianantharajah J, Komiyama NH, McKechanie A, Johnstone M, Blackwood DH, St Clair D, Emes RD, van de Lagemaat LN, Saksida LM, Bussey TJ, Grant SG (2013), “Synaptic scaffold evolution generated components of vertebrate cognitive complexity.” Nat Neurosci 16(1):16-24 Details Oomen CA, Hvoslef-Eide M, Heath CJ, Mar AC, Horner AE, Bussey TJ, Saksida LM (2013), “The touchscreen operant platform for testing working memory and pattern separation in rats and mice.” Nat Protoc 8(10):2006-21 Details Romberg C, Bussey TJ, Saksida LM (2013), “Paying more attention to attention: Towards more comprehensive cognitive translation using mouse models of Alzheimer's disease.” Brain Res Bull 92:49-55 Details Romberg C, Horner AE, Bussey TJ, Saksida LM (2013), “A touch screen-automated cognitive test battery reveals impaired attention, memory abnormalities, and increased response inhibition in the TgCRND8 mouse model of Alzheimer's disease.” Neurobiol Aging 34(3):731-44 Details Romberg C, Yang S, Melani R, Andrews MR, Horner AE, Spillantini MG, Bussey TJ, Fawcett JW, Pizzorusso T, Saksida LM (2013), “Depletion of perineuronal nets enhances recognition memory and long-term depression in the perirhinal cortex.” J Neurosci 33(16):7057-65 Details Ryan TJ, Kopanitsa MV, Indersmitten T, Nithianantharajah J, Afinowi NO, Pettit C, Stanford LE, Sprengel R, Saksida LM, Bussey TJ, O'Dell TJ, Grant SG, Komiyama NH (2013), “Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior.” Nat Neurosci 16(1):25-32 Details Saksida LM (2013), “Shining a light on memory representations.” Trends Cogn Sci 17(10):486-7 Details 2012Barense MD, Groen II, Lee AC, Yeung LK, Brady SM, Gregori M, Kapur N, Bussey TJ, Saksida LM, Henson RN (2012), “Intact memory for irrelevant information impairs perception in amnesia.” Neuron 75(1):157-67 Details Barkus C, Feyder M, Graybeal C, Wright T, Wiedholz L, Izquierdo A, Kiselycznyk C, Schmitt W, Sanderson DJ, Rawlins JN, Saksida LM, Bussey TJ, Sprengel R, Bannerman D, Holmes A (2012), “Do GluA1 knockout mice exhibit behavioral abnormalities relevant to the negative or cognitive symptoms of schizophrenia and schizoaffective disorder?” Neuropharmacology 62(3):1263-72 Details Bussey TJ, Holmes A, Lyon L, Mar AC, McAllister KA, Nithianantharajah J, Oomen CA, Saksida LM (2012), “New translational assays for preclinical modelling of cognition in schizophrenia: the touchscreen testing method for mice and rats.” Neuropharmacology 62(3):1191-203 Details Coba MP, Komiyama NH, Nithianantharajah J, Kopanitsa MV, Indersmitten T, Skene NG, Tuck EJ, Fricker DG, Elsegood KA, Stanford LE, Afinowi NO, Saksida LM, Bussey TJ, O'Dell TJ, Grant SG (2012), “TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function.” J Neurosci 32(40):13987-99 Details Cowell RA, Bussey TJ, Saksida LM (2012), “Empiricists are from Venus, modelers are from Mars: Reconciling experimental and computational approaches in cognitive neuroscience.” Neurosci Biobehav Rev 36(10):2371-9 Details Forwood SE, Cowell RA, Bussey TJ, Saksida LM (2012), “Multiple cognitive abilities from a single cortical algorithm.” J Cogn Neurosci 24(9):1807-25 Details Lyon L, Saksida LM, Bussey TJ (2012), “Spontaneous object recognition and its relevance to schizophrenia: a review of findings from pharmacological, genetic, lesion and developmental rodent models.” Psychopharmacology (Berl) 220(4):647-72 Details Romberg C, McTighe SM, Heath CJ, Whitcomb DJ, Cho K, Bussey TJ, Saksida LM (2012), “False recognition in a mouse model of Alzheimer's disease: rescue with sensory restriction and memantine.” Brain 135(Pt 7):2103-14 Details 2011Bartko SJ, Romberg C, White B, Wess J, Bussey TJ, Saksida LM (2011), “Intact attentional processing but abnormal responding in M1 muscarinic receptor-deficient mice using an automated touchscreen method.” Neuropharmacology 61(8):1366-78 Details Bartko SJ, Vendrell I, Saksida LM, Bussey TJ (2011), “A computer-automated touchscreen paired-associates learning (PAL) task for mice: impairments following administration of scopolamine or dicyclomine and improvements following donepezil.” Psychopharmacology (Berl) 214(2):537-48 Details Bekinschtein P, Oomen CA, Saksida LM, Bussey TJ (2011), “Effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: BDNF as a critical variable?” Semin Cell Dev Biol 22(5):536-42 Details Graybeal C, Feyder M, Schulman E, Saksida LM, Bussey TJ, Brigman JL, Holmes A (2011), “Paradoxical reversal learning enhancement by stress or prefrontal cortical damage: rescue with BDNF.” Nat Neurosci 14(12):1507-9 Details Lederle L, Weber S, Wright T, Feyder M, Brigman JL, Crombag HS, Saksida LM, Bussey TJ, Holmes A (2011), “Reward-related behavioral paradigms for addiction research in the mouse: performance of common inbred strains.” PLoS One 6(1):e15536 Details McCarthy AD, Owens IJ, Bansal AT, McTighe SM, Bussey TJ, Saksida LM (2011), “FK962 and donepezil act synergistically to improve cognition in rats: potential as an add-on therapy for Alzheimer's disease.” Pharmacol Biochem Behav 98(1):76-80 Details Romberg C, Mattson MP, Mughal MR, Bussey TJ, Saksida LM (2011), “Impaired attention in the 3xTgAD mouse model of Alzheimer's disease: rescue by donepezil (Aricept).” J Neurosci 31(9):3500-7 Details 2010Barense MD, Rogers TT, Bussey TJ, Saksida LM, Graham KS (2010), “Influence of conceptual knowledge on visual object discrimination: insights from semantic dementia and MTL amnesia.” Cereb Cortex 20(11):2568-82 Details Bartko SJ, Cowell RA, Winters BD, Bussey TJ, Saksida LM (2010), “Heightened susceptibility to interference in an animal model of amnesia: Impairment in encoding, storage, retrieval - or all three?” Neuropsychologia 48(10):2987-2997 Details Brigman JL, Mathur P, Harvey-White J, Izquierdo A, Saksida LM, Bussey TJ, Fox S, Deneris E, Murphy DL, Holmes A (2010), “Pharmacological or genetic inactivation of the serotonin transporter improves reversal learning in mice.” Cereb Cortex 20(8):1955-63 Details Cowell RA, Bussey TJ, Saksida LM (2010), “Components of recognition memory: Dissociable cognitive processes or just differences in representational complexity?” Hippocampus 20(11):1245-62 Details Creer DJ, Romberg C, Saksida LM, van Praag H, Bussey TJ (2010), “Running enhances spatial pattern separation in mice.” Proc Natl Acad Sci U S A 107(5):2367-72 Details Saksida LM, Bussey TJ (2010), “The representational-hierarchical view of amnesia: translation from animal to human.” Neuropsychologia 48(8):2370-84 Details Saksida LM, Bussey TJ (2010), “Animal models of amnesia.” Neuropsychologia 48(8):2231-3 Details Talpos JC, McTighe SM, Dias R, Saksida LM, Bussey TJ (2010), “Trial-unique, delayed nonmatching-to-location (TUNL): a novel, highly hippocampus-dependent automated touchscreen test of location memory and pattern separation.” Neurobiol Learn Mem 94(3):341-52 Details Winters BD, Bartko SJ, Saksida LM, Bussey TJ (2010), “Muscimol, AP5, or scopolamine infused into perirhinal cortex impairs two-choice visual discrimination learning in rats.” Neurobiol Learn Mem 93(2):221-8 Details Winters BD, Saksida LM, Bussey TJ (2010), “Implications of animal object memory research for human amnesia.” Neuropsychologia 48(8):2251-61 Details 2009Brigman JL, Ihne J, Saksida LM, Bussey TJ, Holmes A (2009), “Effects of Subchronic Phencyclidine (PCP) Treatment on Social Behaviors, and Operant Discrimination and Reversal Learning in C57BL/6J Mice.” Front Behav Neurosci 3:2 Details Clelland CD, Choi M, Romberg C, Clemenson GD Jr, Fragniere A, Tyers P, Jessberger S, Saksida LM, Barker RA, Gage FH, Bussey TJ (2009), “A functional role for adult hippocampal neurogenesis in spatial pattern separation.” Science 325(5937):210-3 Details Karlsson RM, Tanaka K, Saksida LM, Bussey TJ, Heilig M, Holmes A (2009), “Assessment of glutamate transporter GLAST (EAAT1)-deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia.” Neuropsychopharmacology 34(6):1578-89 Details McTighe SM, Mar AC, Romberg C, Bussey TJ, Saksida LM (2009), “A new touchscreen test of pattern separation: effect of hippocampal lesions.” Neuroreport 20(9):881-5 Details Saksida LM (2009), “Neuroscience. Remembering outside the box.” Science 325(5936):40-1 Details Talpos JC, Winters BD, Dias R, Saksida LM, Bussey TJ (2009), “A novel touchscreen-automated paired-associate learning (PAL) task sensitive to pharmacological manipulation of the hippocampus: a translational rodent model of cognitive impairments in neurodegenerative disease.” Psychopharmacology (Berl) 205(1):157-68 Details 2008Brigman JL, Feyder M, Saksida LM, Bussey TJ, Mishina M, Holmes A (2008), “Impaired discrimination learning in mice lacking the NMDA receptor NR2A subunit.” Learn Mem 15(2):50-4 Details Bussey TJ, Padain TL, Skillings EA, Winters BD, Morton AJ, Saksida LM (2008), “The touchscreen cognitive testing method for rodents: how to get the best out of your rat.” Learn Mem 15(7):516-23 Details Hefner K, Whittle N, Juhasz J, Norcross M, Karlsson RM, Saksida LM, Bussey TJ, Singewald N, Holmes A (2008), “Impaired fear extinction learning and cortico-amygdala circuit abnormalities in a common genetic mouse strain.” J Neurosci 28(32):8074-85 Details Talpos JC, Dias R, Bussey TJ, Saksida LM (2008), “Hippocampal lesions in rats impair learning and memory for locations on a touch-sensitive computer screen: The "ASAT" task.” Behav Brain Res 192(2):216-25 Details Winters BD, Saksida LM, Bussey TJ (2008), “Object recognition memory: Neurobiological mechanisms of encoding, consolidation and retrieval.” Neurosci Biobehav Rev 32(5):1055-70 Details 2007Bartko SJ, Winters BD, Cowell RA, Saksida LM, Bussey TJ (2007), “Perirhinal cortex resolves feature ambiguity in configural object recognition and perceptual oddity tasks.” Learn Mem 14(12):821-32 Details Bartko SJ, Winters BD, Cowell RA, Saksida LM, Bussey TJ (2007), “Perceptual functions of perirhinal cortex in rats: zero-delay object recognition and simultaneous oddity discriminations.” J Neurosci 27(10):2548-59 Details Bussey TJ, Saksida LM (2007), “Memory, perception, and the ventral visual-perirhinal-hippocampal stream: thinking outside of the boxes.” Hippocampus 17(9):898-908 Details Forwood SE, Bartko SJ, Saksida LM, Bussey TJ (2007), “Rats spontaneously discriminate purely visual, two-dimensional stimuli in tests of recognition memory and perceptual oddity.” Behav Neurosci 121(5):1032-42 Details Murray EA, Bussey TJ, Saksida LM (2007), “Visual perception and memory: a new view of medial temporal lobe function in primates and rodents.” Annu Rev Neurosci 30:99-122 Details Saksida LM, Bussey TJ, Buckmaster CA, Murray EA (2007), “Impairment and facilitation of transverse patterning after lesions of the perirhinal cortex and hippocampus, respectively.” Cereb Cortex 17(1):108-15 Details Winters BD, Bartko SJ, Saksida LM, Bussey TJ (2007), “Scopolamine infused into perirhinal cortex improves object recognition memory by blocking the acquisition of interfering object information.” Learn Mem 14(9):590-6 Details 2006Bussey TJ, Saksida LM, Murray EA (2006), “Perirhinal cortex and feature-ambiguous discriminations.” Learn Mem 13(2):103-5; author reply 106-7 Details Cowell RA, Bussey TJ, Saksida LM (2006), “Why does brain damage impair memory? A connectionist model of object recognition memory in perirhinal cortex.” J Neurosci 26(47):12186-97 Details Graham KS, Scahill VL, Hornberger M, Barense MD, Lee AC, Bussey TJ, Saksida LM (2006), “Abnormal categorization and perceptual learning in patients with hippocampal damage.” J Neurosci 26(29):7547-54 Details Graham KS, Scahill VL, Hornberger M, Barense MD, Lee ACH, Bussey TJ, Saksida LM (2006), “Abnormal categorization and perceptual learning in patients with hippocampal damage” Journal of Neuroscience 26:7547-54 Izquierdo A, Wiedholz LM, Millstein RA, Yang RJ, Bussey TJ, Saksida LM, Holmes A (2006), “Genetic and dopaminergic modulation of reversal learning in a touchscreen-based operant procedure for mice.” Behav Brain Res 171(2):181-8 Details Morton AJ, Skillings E, Bussey TJ, Saksida LM (2006), “Measuring cognitive deficits in disabled mice using an automated interactive touchscreen system.” Nat Methods 3(10):767 Details Saksida LM, Bussey TJ, Buckmaster CA, Murray EA (2006), “No effect of hippocampal lesions on perirhinal cortex-dependent feature-ambiguous visual discriminations.” Hippocampus 16(4):421-30 Details Winters BD, Saksida LM, Bussey TJ (2006), “Paradoxical facilitation of object recognition memory after infusion of scopolamine into perirhinal cortex: implications for cholinergic system function.” J Neurosci 26(37):9520-9 Details 2005Barense MD, Bussey TJ, Lee AC, Rogers TT, Davies RR, Saksida LM, Murray EA, Graham KS (2005), “Functional specialization in the human medial temporal lobe.” J Neurosci 25(44):10239-46 Details Brigman JL, Bussey TJ, Saksida LM, Rothblat LA (2005), “Discrimination of multidimensional visual stimuli by mice: intra- and extradimensional shifts.” Behav Neurosci 119(3):839-42 Details Bussey TJ, Saksida LM (2005), “Object memory and perception in the medial temporal lobe: an alternative approach.” Curr Opin Neurobiol 15(6):730-7 Details Bussey TJ, Saksida LM, Murray EA (2005), “The perceptual-mnemonic/feature conjunction model of perirhinal cortex function.” Q J Exp Psychol B 58(3-4):269-82 Details Lee AC, Bussey TJ, Murray EA, Saksida LM, Epstein RA, Kapur N, Hodges JR, Graham KS (2005), “Perceptual deficits in amnesia: challenging the medial temporal lobe 'mnemonic' view.” Neuropsychologia 43(1):1-11 Details 2004Winters BD, Forwood SE, Cowell RA, Saksida LM, Bussey TJ (2004), “Double dissociation between the effects of peri-postrhinal cortex and hippocampal lesions on tests of object recognition and spatial memory: heterogeneity of function within the temporal lobe.” J Neurosci 24(26):5901-8 Details 2003Bussey TJ, Saksida LM, Murray EA (2003), “Impairments in visual discrimination after perirhinal cortex lesions: testing 'declarative' vs. 'perceptual-mnemonic' views of perirhinal cortex function.” Eur J Neurosci 17(3):649-60 Details Plaisted K, Saksida L, Alcántara J, Weisblatt E (2003), “Towards an understanding of the mechanisms of weak central coherence effects: experiments in visual configural learning and auditory perception.” Philos Trans R Soc Lond B Biol Sci 358(1430):375-86 Details 2002Bussey TJ, Saksida LM (2002), “The organization of visual object representations: a connectionist model of effects of lesions in perirhinal cortex.” Eur J Neurosci 15(2):355-64 Details Bussey TJ, Saksida LM, Murray EA (2002), “Perirhinal cortex resolves feature ambiguity in complex visual discriminations.” Eur J Neurosci 15(2):365-74 Details 2001Bussey TJ, Saksida LM, Rothblat LA (2001), “Discrimination of computer-graphic stimuli by mice: a method for the behavioral characterization of transgenic and gene-knockout models.” Behav Neurosci 115(4):957-60 Details 2000Murray EA, Bussey TJ, Hampton RR, Saksida LM (2000), “The parahippocampal region and object identification.” Ann N Y Acad Sci 911:166-74 Details Murray, EA, Bussey, TJ, Hampton, RR,Saksida, LM (2000), “The parahippocamal region and object identification.” Annals of the New York Academy of Sciences 119: 166-174 1999Saksida LM (1999), “Effects of similarity and experience on discrimination learning: a nonassociative connectionist model of perceptual learning.” J Exp Psychol Anim Behav Process 25(3):308-23 Details Saksida, LM, Raymond, SM, Touretzky, DS (1999), “Shaping robot behavior using principles from instrumental conditioning” Robotics and Autonomous Systems 22: 231-249 1997Saksida, LM, Touretzky, DS (1997), “Application of a model of instrumental conditioning to mobile robot control. ” Sensor Fusion and Decentralized Control in Autonomous Robotic Systems: Society of Photo-Optical Instrumentation Engineers (SPIE). 3209: 55-66 Touretzky, DS, Saksida, LM (1997), “Operant conditioning in Skinnerbots” Adaptive Behavior 5: 219-248 1996Touretzky, DS, Saksida, LM (1996), “Skinnerbots” From Animals to Animats 4: 285-294 1994.Wilkie, DM, Saksida, LM, Samson, P (1994), “Properties of time-place learning by pigeons, Columba livia” Behavioral Processes 31: 39-56 Galea LA, Saksida L, Kavaliers M, Ossenkopp KP (1994), “Naloxone facilitates spatial learning in a water-maze task in female, but not male, adult nonbreeding meadow voles.” Pharmacol Biochem Behav 47(2):265-71 Details Wilkie DM, Saksida LM (1994), “The spatial distribution of pigeons' target detection.” Behav Brain Res 60(2):137-40 Details Wilkie, DM, Mak, T, Saksida, LM (1994), “Pigeons' landmark use as revealed in a feature-positive discrimination, digitized landscape touchscreen paradigm.” Behavioral Processes 32: 87-100 1993Saksida LM, Galea LA, Kavaliers M (1993), “Predator-induced opioid and non-opioid mediated analgesia in young meadow voles: sex differences and developmental changes.” Brain Res 617(2):214-9 Details Saksida LM, Galea LA, Kavaliers M (1993), “Antinociceptive effects of the enkephalinase inhibitor, SCH 34826, in the snail, Cepaea nemoralis.” Peptides 14(4):763-5 Details |