Miss Laura Brightman University positionResearch Assisstant DepartmentsDepartment of Biochemistry and Department of Clinical Neurosciences InstitutesWellcome Trust/Cancer Research UK Gurdon Institute of Cancer and Developmental Biology Research ThemesInterestsLooking at an In Vitro model of Prader Willi syndrome, a developmental disorder caused by problems (both deletion and epigenetic) with chromosome 15. Modelling cortical development with human patient IPSC lines.  Dissociated cortical neurons showing glia mediated synapses (red). View image full-size (1920x1440 pixels) Research Focus
EquipmentCalcium imaging Cell culture Computational modelling Confocal microscopy Electrophysiological recording techniques Fluorescence microscopy Immunohistochemistry Intracellular recording Magnetic resonance imaging (MRI) Microscopy Neuropsychological testing Whole cell patch clamp CollaboratorsNo collaborators listed Associated News ItemsPublications2013Samson RS, Ciccarelli O, Kachramanoglou C, Brightman L, Lutti A, Thomas DL, Weiskopf N, Wheeler-Kingshott CA (2013), “Tissue- and column-specific measurements from multi-parameter mapping of the human cervical spinal cord at 3 T.” NMR Biomed 26(12):1823-30 Details |
