Dr Katie Hall PhD
I am principally interested in the field of behavioural neurosciences with a particular focus in understanding how neurodegenerative pathologies cause dementia symptoms and behavioural dysfunction, as well as developing potential neuroprotective therapies for such disorders.
In 2013 I joined Professor Maria Grazia Spillantini’s group, where I characterised a novel model of dementia with Lewy Bodies, which showed forebrain expression of human truncated alpha-synuclein and associated progressive behavioural deficits. I have since joined the lab of Professor Roger Barker in 2014, where my research has focused on therapeutic development and assessing cognitive dysfunction in mouse models of Huntington’s disease. I am currently examining viral vector mediated delivery of GDNF into the striatum of R6/1 and R6/2 mice, as well as the therapeutic potential of RVG9R-p137. Further to this, I am currently working to develop a new rat model of Parkinson's disease with dementia (PDD).
Associated News Items
Hall K, Yang S, Sauchanka O, Spillantini MG, Anichtchik O (2015), “Behavioural deficits in transgenic mice expressing human truncated (1-120 amino acid) alpha-synuclein.” Exp Neurol 264:8-13 Details