Dr Katie Hall PhD![]() University positionResearch Associate DepartmentsDepartment of Clinical Neurosciences InstitutesCambridge Centre for Brain Repair Home pageResearch ThemesInterestsI am principally interested in the field of behavioural neurosciences with a particular focus in understanding how neurodegenerative pathologies cause dementia symptoms and behavioural dysfunction, as well as developing potential neuroprotective therapies for such disorders. In 2013 I joined Professor Maria Grazia Spillantini’s group, where I characterised a novel model of dementia with Lewy Bodies, which showed forebrain expression of human truncated alpha-synuclein and associated progressive behavioural deficits. I have since joined the lab of Professor Roger Barker in 2014, where my research has focused on therapeutic development and assessing cognitive dysfunction in mouse models of Huntington’s disease. I am currently examining viral vector mediated delivery of GDNF into the striatum of R6/1 and R6/2 mice, as well as the therapeutic potential of RVG9R-p137. Further to this, I am currently working to develop a new rat model of Parkinson's disease with dementia (PDD). Research Focus
EquipmentAnimal models Behavioural analysis Confocal microscopy Enzyme assays Fluorescence microscopy Immunohistochemistry Microscopy PhD supervision Protein purification Statistics Stereotaxic surgery Teaching Collaborators
Associated News ItemsPublications2015Hall K, Yang S, Sauchanka O, Spillantini MG, Anichtchik O (2015), “Behavioural deficits in transgenic mice expressing human truncated (1-120 amino acid) alpha-synuclein.” Exp Neurol 264:8-13 Details |