Dr Kate McAllister

Kate McAllister

University position

Visiting Researcher


Department of Psychiatry


Cambridge Intellectual and Developmental Disabilities Research Group and Developmental Psychiatry

Research Themes

Cognitive and Behavioural Neuroscience

Developmental Neuroscience


I am a Visiting Researcher at the Cambridge Intellectual and Developmental Disabilities Research Group as part of the Department of Psychiatry. The focus of my work is the role of mitochondrial dysfunction in ageing and the development of Alzheimer’s disease in Down's Syndrome (DS), I work with Dr Shahid Zaman and Prof Tony Holland on a study that is part of a larger investigation into amyloid build up in people with DS.

Research Focus


Down's syndrome


Alzheimer's disease



Clinical conditions

Alzheimer's disease


Down's Syndrome

Genetic disorders

Learning disabilities


Cross-sectional and cohort studies

Magnetic resonance spectroscopy

Neuropsychological testing



Alison Sleigh

Laura Watson

United Kingdom

Patrick Chinnery

Associated News Items



    Manning KE, McAllister CJ, Ring HA, Finer N, Kelly CL, Sylvester KP, Fletcher PC, Morrell NW, Garnett MR, Manford MR, Holland AJ (2015), “Novel insights into maladaptive behaviours in Prader-Willi syndrome: serendipitous findings from an open trial of vagus nerve stimulation.” J Intellect Disabil Res Details


    McAllister K, Gewin V (2014), “Turning point: Kate McAllister.” Nature 515(7527):455 Details


    de Souza MA, McAllister C, Suttie M, Perrotta C, Mattina T, Faravelli F, Forzano F, Holland A, Hammond P (2013), “Growth hormone, gender and face shape in prader-willi syndrome.” Am J Med Genet A Details

    McAllister CJ, Kelly CL, Manning KE, Holland AJ (2013), “Participant experience of invasive research in adults with intellectual disability.” J Med Ethics Details

    Phillips AC, Sleigh A, McAllister CJ, Brage S, Carpenter TA, Kemp GJ, Holland AJ (2013), “Defective Mitochondrial Function In Vivo in Skeletal Muscle in Adults with Down's Syndrome: A (31)P-MRS Study.” PLoS One 8(12):e84031 Details

    Wood NI, McAllister CJ, Cuesta M, Aungier J, Fraenkel E, Morton AJ (2013), “Adaptation to Experimental Jet-Lag in R6/2 Mice despite Circadian Dysrhythmia.” PLoS One 8(2):e55036 Details


    McAllister CJ (2012), “Meeting reports: The 24th Cambridge Neuroscience Seminar” Br Neurosci Assoc Bull 65: 32-33

    Siaperas P, Ring HA, McAllister CJ, Henderson S, Barnett A, Watson P, Holland AJ (2012), “Atypical movement performance and sensory integration in Asperger's syndrome.” J Autism Dev Disord 42(5):718-25 Details


    Goodman AO, Rogers L, Pilsworth S, McAllister CJ, Shneerson JM, Morton AJ, Barker RA (2011), “Asymptomatic sleep abnormalities are a common early feature in patients with Huntington's disease.” Curr Neurol Neurosci Rep 11(2):211-7 Details

    McAllister CJ, Whittington JE (2011), “A short clinical overview of Prader–Willi syndrome” Clinical Obesity 1 (4-6): 184-186

    McAllister CJ, Whittington JE, Holland AJ (2011), “Development of the eating behaviour in Prader-Willi Syndrome: advances in our understanding.” Int J Obes (Lond) 35(2):188-97 Details


    Butler JV, Whittington JE, Holland AJ, McAllister CJ, Goldstone AP (2010), “The transition between the phenotypes of Prader-Willi syndrome during infancy and early childhood.” Dev Med Child Neurol 52(6):e88-93 Details

    Maywood ES, Fraenkel E, McAllister CJ, Wood N, Reddy AB, Hastings MH, Morton AJ (2010), “Disruption of peripheral circadian timekeeping in a mouse model of Huntington's disease and its restoration by temporally scheduled feeding.” J Neurosci 30(30):10199-204 Details

    Wood NI, Carta V, Milde S, Skillings EA, McAllister CJ, Ang YL, Duguid A, Wijesuriya N, Afzal SM, Fernandes JX, Leong TW, Morton AJ (2010), “Responses to environmental enrichment differ with sex and genotype in a transgenic mouse model of Huntington's disease.” PLoS One 5(2):e9077 Details