Mr Jasdip Singh Dulai

University position

PhD student
Supervised by Ewan Smith

Departments

Department of Pharmacology

Email

jsd53@cam.ac.uk

Home page

https://www.phar.cam.ac.uk/

Research Themes

Cellular and Molecular Neuroscience

Systems and Computational Neuroscience

Interests

My research is orientated towards the more commonly observed nociceptive pain pathway, with a specific interest in inflammation. Using both in silico screening (docking models) and in vitro (electrophysiology) to validate findings.

The overall aim of my PhD project is to identify potential 'druggable' pocket(s) and novel small molecule chemical scaffolds as potential, selective inhibitors of acid-sensing ion channel 3 (ASIC3).

Research Focus

Keywords

Ion Channels

Electrophysiology

Computational Models

Inflammation

Pain

Clinical conditions

Pain

Equipment

Cell culture

Computational modelling

Electrophysiological recording techniques

Whole cell patch clamp

Collaborators

Cambridge

Taufiq Rahman

Ewan Smith

Associated News Items


    Publications

    2019

    Wichmann L, Dulai JS, Marles-Wright J, Maxeiner S, Szczesniak PP, Manzini I, Althaus M (2019), “An extracellular acidic cleft confers profound H+-sensitivity to epithelial sodium channels containing the δ-subunit in Xenopus laevis” J Biol Chem 294(33): 12507-12520