Dr John Stockley University positionResearch Associate DepartmentsHome pageResearch ThemesInterestsI am interested in using in vitro systems to model and understand complex neuron and glial interactions, particularly the interaction between oligodendrocytes, their precursors and neuronal axons for CNS repair as well as understanding memory. I am also interested in the relationship between light, cells and their environment to improve methodologies such as optogenetics, live cell imaging and flow cytometry. Research Focus
EquipmentAutomated image analysis Bioinformatics Cell culture Cloning Confocal microscopy Fluorescence microscopy Fluorescent in situ hybridisation High throughput screening Immunohistochemistry Media Formulation Microscopy Optogenetics Western Blotting CollaboratorsNo collaborators listed Associated News ItemsPublications2013Lundgaard I, Luzhynskaya A, Stockley JH, Wang Z, Evans KA, Swire M, Volbracht K, Gautier HO, Franklin RJ, Ffrench-Constant C, Attwell D, Káradóttir RT (2013), “Neuregulin and BDNF Induce a Switch to NMDA Receptor-Dependent Myelination by Oligodendrocytes.” PLoS Biol 11(12):e1001743 Details 2012Káradóttir RT, Stockley JH (2012), “Deconstructing myelination: it all comes down to size.” Nat Methods 9(9):883-4 Details 2008Stockley JH, O'Neill C (2008), “Understanding BACE1: essential protease for amyloid-beta production in Alzheimer's disease.” Cell Mol Life Sci 65(20):3265-89 Details 2007Stockley JH, O'Neill C (2007), “The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.” Biochem Soc Trans 35(Pt 3):574-6 Details 2006Stockley JH, Ravid R, O'Neill C (2006), “Altered beta-secretase enzyme kinetics and levels of both BACE1 and BACE2 in the Alzheimer's disease brain.” FEBS Lett 580(28-29):6550-60 Details |