Professor Jean-Claude Baron

Interests

My research focuses on the pathophysiology of ischaemic stroke and the mechanisms underlying subsequent deterioration or recovery, including neuronal damage, tissue inflammation and long-term plasticity processes. In terms of methodology, my approach is characterized by 1) combining brain imaging, both structural and functional (PET and fMRI) and assessment of performance measured using behavioural, cognitive or psychophysical tools; and 2) undertaking parallel studies in stroke patients and animal models, in the latter including microPET, in vitro autoradiographic and post mortem histopathologic techniques to inform the human studies.

Mapping the hypoxic brain tissue in the acute stage of stroke using PET and a selective hypoxia tracer
Mapping the hypoxic brain tissue in the acute stage of stroke using PET and a selective hypoxia tracer
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Research Focus

Keywords

stroke

functional recovery

plasticity

neuroimaging

PET

Clinical conditions

Aphasia

Cerebrovascular disorders

Dementia

Stroke

Equipment

Behavioural analysis

Computerised tomography

Cross-sectional and cohort studies

Haemodynamic monitoring

Magnetic resonance imaging (MRI)

Microscopy

Positron Emission Tomography (PET)

Collaborators

Cambridge

Elizabeth Warburton

Associated News Items


    Key publications

    Calautti C, Naccarato M, Jones PS, Day DJ, Carpenter TA, Bullmore ET, Warburton EA, Baron JC (2007), “The relationship between motor deficit and hemisphere activation balance after stroke” NeuroImage 34:322-331

    Takasawa M, Beech JS, Fryer TDF, Hughes JL Igase K, Jones PS, Smith R, Aigbirihio FI, Menon DK, Clark JC, Baron J-C (2007), “Imaging of Brain Hypoxia in Permanent and Temporary MCA Occlusion in the Rat Using 18F-Fluoromisonidazole and PET” J Cereb Blood Flow Metab 27:679-89

    Guadagno JV, Jones PS, Fryer TD, Barret O, Aigbirhio FI, Carpenter TA, Price CJ, Gillard JH, Warburton EA, Baron JC (2006), “Local relationships between restricted water diffusion and oxygen consumption in the ischaemic human brain” Stroke 37:1741-48 Details

    Publications

    2014

    Alawneh JA, Moustafa RR, Marrapu ST, Jensen-Kondering U, Morris RS, Jones PS, Aigbirhio FI, Fryer TD, Carpenter TA, Warburton EA, Baron JC (2014), “Diffusion and perfusion correlates of the 18F-MISO PET lesion in acute stroke: pilot study.” Eur J Nucl Med Mol Imaging 41(4):736-44 Details

    Baron JC, Farid K, Dolan E, Turc G, Marrapu ST, O'Brien E, Aigbirhio FI, Fryer TD, Menon DK, Warburton EA, Hong YT (2014), “Diagnostic utility of amyloid PET in cerebral amyloid angiopathy-related symptomatic intracerebral hemorrhage.” J Cereb Blood Flow Metab 34(5):753-8 Details

    Baron JC, Yamauchi H, Fujioka M, Endres M (2014), “Selective neuronal loss in ischemic stroke and cerebrovascular disease.” J Cereb Blood Flow Metab 34(1):2-18 Details

    Charidimou A, Jaunmuktane Z, Baron JC, Burnell M, Varlet P, Peeters A, Xuereb J, Jäger R, Brandner S, Werring DJ (2014), “White matter perivascular spaces: an MRI marker in pathology-proven cerebral amyloid angiopathy?” Neurology 82(1):57-62 Details

    Cheng B, Forkert ND, Zavaglia M, Hilgetag CC, Golsari A, Siemonsen S, Fiehler J, Pedraza S, Puig J, Cho TH, Alawneh J, Baron JC, Ostergaard L, Gerloff C, Thomalla G (2014), “Influence of Stroke Infarct Location on Functional Outcome Measured by the Modified Rankin Scale.” Stroke Details

    Hong YT, Veenith T, Dewar D, Outtrim JG, Mani V, Williams C, Pimlott S, Hutchinson PJ, Tavares A, Canales R, Mathis CA, Klunk WE, Aigbirhio FI, Coles JP, Baron JC, Pickard JD, Fryer TD, Stewart W, Menon DK (2014), “Amyloid imaging with carbon 11-labeled Pittsburgh compound B for traumatic brain injury.” JAMA Neurol 71(1):23-31 Details

    Seners P, Turc G, Oppenheim C, Baron JC (2014), “Incidence, causes and predictors of neurological deterioration occurring within 24?h following acute ischaemic stroke: a systematic review with pathophysiological implications.” J Neurol Neurosurg Psychiatry Details

    Seners P, Turc G, Tisserand M, Legrand L, Labeyrie MA, Calvet D, Meder JF, Mas JL, Oppenheim C, Baron JC (2014), “Unexplained early neurological deterioration after intravenous thrombolysis: incidence, predictors, and associated factors.” Stroke 45(7):2004-9 Details

    Sharma N, Baron JC (2014), “Effects of healthy ageing on activation pattern within the primary motor cortex during movement and motor imagery: an fMRI study.” PLoS One 9(6):e88443 Details

    Tisserand M, Malherbe C, Turc G, Legrand L, Edjlali M, Labeyrie MA, Seners P, Mas JL, Méder JF, Baron JC, Oppenheim C (2014), “Is white matter more prone to diffusion lesion reversal after thrombolysis?” Stroke 45(4):1167-9 Details

    2013

    Agarwal S, Scoffings DJ, Jones PS, Marrapu ST, Barry PJ, O'Brien EW, Baron JC, Warburton EA (2013), “Interaction of age with the ischaemic penumbra, leptomeningeal collateral circulation and haemodynamic variables in acute stroke: a pilot study.” J Neurol Neurosurg Psychiatry 84(3):271-6 Details

    Apoil M, Turc G, Tisserand M, Calvet D, Naggara O, Domigo V, Baron JC, Oppenheim C, Touzé E (2013), “Clinical and magnetic resonance imaging predictors of very early neurological response to intravenous thrombolysis in patients with middle cerebral artery occlusion.” J Am Heart Assoc 2(6):e000511 Details

    Baron JC, Macrae IM, Adams HP Jr, Dirnagl U (2013), “ESC-BRAIN: experimental and clinical stroke research--do they connect?. meeting report of the ESC-BRAIN joint symposium held in London and Shanghai in May 2013.” Cerebrovasc Dis 36(4):306-21 Details

    Carrera E, Jones PS, Morris RS, Alawneh J, Hong YT, Aigbirhio FI, Fryer TD, Carpenter TA, Warburton EA, Baron JC (2013), “Is neural activation within the rescued penumbra impeded by selective neuronal loss?” Brain 136(Pt 6):1816-29 Details

    Charidimou A, Baron JC, Werring DJ (2013), “Cerebral amyloid angiopathy and transient focal neurological episodes.” Cerebrovasc Dis 36(3):245-6 Details

    Charidimou A, Baron JC, Werring DJ (2013), “Transient focal neurological episodes, cerebral amyloid angiopathy, and intracerebral hemorrhage risk: looking beyond TIAs.” Int J Stroke 8(2):105-8 Details

    Charidimou A, Jäger RH, Fox Z, Peeters A, Vandermeeren Y, Laloux P, Baron JC, Werring DJ (2013), “Prevalence and mechanisms of cortical superficial siderosis in cerebral amyloid angiopathy.” Neurology 81(7):626-32 Details

    Charidimou A, Meegahage R, Fox Z, Peeters A, Vandermeeren Y, Laloux P, Baron JC, Jäger HR, Werring DJ (2013), “Enlarged perivascular spaces as a marker of underlying arteriopathy in intracerebral haemorrhage: a multicentre MRI cohort study.” J Neurol Neurosurg Psychiatry 84(6):624-9 Details

    Charidimou A, Peeters AP, Jäger R, Fox Z, Vandermeeren Y, Laloux P, Baron JC, Werring DJ (2013), “Cortical superficial siderosis and intracerebral hemorrhage risk in cerebral amyloid angiopathy.” Neurology 81(19):1666-73 Details

    Chollet F, Cramer SC, Stinear C, Kappelle LJ, Baron JC, Weiller C, Azouvi P, Hommel M, Sabatini U, Moulin T, Tardy J, Valenti M, Montgomery S, Adams H Jr (2013), “Pharmacological therapies in post stroke recovery: recommendations for future clinical trials.” J Neurol Details

    Clatworthy PL, Warburton EA, Tolhurst DJ, Baron JC (2013), “Visual contrast sensitivity deficits in 'normal' visual field of patients with homonymous visual field defects due to stroke: a pilot study.” Cerebrovasc Dis 36(5-6):329-35 Details

    del Campo N, Fryer TD, Hong YT, Smith R, Brichard L, Acosta-Cabronero J, Chamberlain SR, Tait R, Izquierdo D, Regenthal R, Dowson J, Suckling J, Baron JC, Aigbirhio FI, Robbins TW, Sahakian BJ, Müller U (2013), “A positron emission tomography study of nigro-striatal dopaminergic mechanisms underlying attention: implications for ADHD and its treatment.” Brain 136(Pt 11):3252-70 Details

    Ejaz S, Williamson DJ, Ahmed T, Sitnikov S, Hong YT, Sawiak SJ, Fryer TD, Aigbirhio FI, Baron JC (2013), “Characterizing infarction and selective neuronal loss following temporary focal cerebral ischemia in the rat: a multi-modality imaging study.” Neurobiol Dis 51:120-32 Details

    Hermitte L, Cho TH, Ozenne B, Nighoghossian N, Mikkelsen IK, Ribe L, Baron JC, Østergaard L, Derex L, Hjort N, Fiehler J, Pedraza S, Hermier M, Maucort-Boulch D, Berthezène Y (2013), “Very low cerebral blood volume predicts parenchymal hematoma in acute ischemic stroke.” Stroke 44(8):2318-20 Details

    Saver JL, Jovin TG, Smith WS, Albers GW, Baron JC, Boltze J, Broderick JP, Davis LA, Demchuk AM, DeSena S, Fiehler J, Gorelick PB, Hacke W, Holt B, Jahan R, Jing H, Khatri P, Kidwell CS, Lees KR, Lev MH, Liebeskind DS, Luby M, Lyden P, Megerian JT, Mocco J, Muir KW, Rowley HA, Ruedy RM, Savitz SI, Sipelis VJ, Shimp SK 3rd, Wechsler LR, Wintermark M, Wu O, Yavagal DR, Yoo AJ, STAIR VIII Consortium (2013), “Stroke treatment academic industry roundtable: research priorities in the assessment of neurothrombectomy devices.” Stroke 44(12):3596-601 Details

    Sharma N, Baron JC (2013), “Does motor imagery share neural networks with executed movement: a multivariate fMRI analysis.” Front Hum Neurosci 7:564 Details

    Williamson DJ, Ejaz S, Sitnikov S, Fryer TD, Sawiak SJ, Burke P, Baron JC, Aigbirhio FI (2013), “A comparison of four PET tracers for brain hypoxia mapping in a rodent model of stroke.” Nucl Med Biol 40(3):338-44 Details

    Wintermark M, Albers GW, Broderick JP, Demchuk AM, Fiebach JB, Fiehler J, Grotta JC, Houser G, Jovin TG, Lees KR, Lev MH, Liebeskind DS, Luby M, Muir KW, Parsons MW, von Kummer R, Wardlaw JM, Wu O, Yoo AJ, Alexandrov AV, Alger JR, Aviv RI, Bammer R, Baron JC, Calamante F, Campbell BC, Carpenter TC, Christensen S, Copen WA, Derdeyn CP, Haley EC Jr, Khatri P, Kudo K, Lansberg MG, Latour LL, Lee TY, Leigh R, Lin W, Lyden P, Mair G, Menon BK, Michel P, Mikulik R, Nogueira RG, Ostergaard L, Pedraza S, Riedel CH, Rowley HA, Sanelli PC, Sasaki M, Saver JL, Schaefer PW, Schellinger PD, Tsivgoulis G, Wechsler LR, White PM, Zaharchuk G, Zaidat OO, Davis SM, Donnan GA, Furlan AJ, Hacke W, Kang DW, Kidwell C, Thijs VN, Thomalla G, Warach SJ, Stroke Imaging Research (STIR) and Virtual International Stroke Trials Archive (VISTA)-Imaging Investigators (2013), “Acute Stroke Imaging Research Roadmap II.” Stroke 44(9):2628-39 Details

    2012

    Baron JC, Jones T (2012), “Oxygen metabolism, oxygen extraction and positron emission tomography: Historical perspective and impact on basic and clinical neuroscience.” Neuroimage 61(2):492-504 Details

    Caroli A, Prestia A, Chen K, Ayutyanont N, Landau SM, Madison CM, Haense C, Herholz K, Nobili F, Reiman EM, Jagust WJ, Frisoni GB, EADC-PET Consortium, NEST-DD, and Alzheimer's Disease Neuroimaging Initiative (2012), “Summary metrics to assess Alzheimer disease-related hypometabolic pattern with 18F-FDG PET: head-to-head comparison.” J Nucl Med 53(4):592-600 Details

    Charidimou A, Peeters A, Fox Z, Gregoire SM, Vandermeeren Y, Laloux P, Jäger HR, Baron JC, Werring DJ (2012), “Spectrum of transient focal neurological episodes in cerebral amyloid angiopathy: multicentre magnetic resonance imaging cohort study and meta-analysis.” Stroke 43(9):2324-30 Details

    Fouquet M, Desgranges B, La Joie R, Rivière D, Mangin JF, Landeau B, Mézenge F, Pélerin A, de La Sayette V, Viader F, Baron JC, Eustache F, Chételat G (2012), “Role of hippocampal CA1 atrophy in memory encoding deficits in amnestic Mild Cognitive Impairment.” Neuroimage 59(4):3309-15 Details

    Geva S, Baron JC, Jones PS, Price CJ, Warburton EA (2012), “A comparison of VLSM and VBM in a cohort of patients with post-stroke aphasia.” Neuroimage Clin 1(1):37-47 Details

    Geva S, Jones PS, Crinion JT, Price CJ, Baron JC, Warburton EA (2012), “The effect of aging on the neural correlates of phonological word retrieval.” J Cogn Neurosci 24(11):2135-46 Details

    Hughes JL, Jones PS, Beech JS, Wang D, Menon DK, Aigbirhio FI, Fryer TD, Baron JC (2012), “A microPET study of the regional distribution of [11C]-PK11195 binding following temporary focal cerebral ischemia in the rat. Correlation with post mortem mapping of microglia activation.” Neuroimage 59(3):2007-16 Details

    Jensen-Kondering U, Baron JC (2012), “Oxygen imaging by MRI: can blood oxygen level-dependent imaging depict the ischemic penumbra?” Stroke 43(8):2264-9 Details

    Jones T, Rabiner EA, PET Research Advisory Company (2012), “The development, past achievements, and future directions of brain PET.” J Cereb Blood Flow Metab 32(7):1426-54 Details

    Lewis DH, Toney LK, Baron JC (2012), “Nuclear medicine in cerebrovascular disease.” Semin Nucl Med 42(6):387-405 Details

    Pomeroy VM, Rowe P, Baron JC, Clark A, Sealy R, Ugbolue UC, Kerr A, SWIFT Cast Investigators (2012), “The SWIFT Cast trial protocol: a randomized controlled evaluation of the efficacy of an ankle-foot cast on walking recovery early after stroke and the neural-biomechanical correlates of response.” Int J Stroke 7(1):86-93 Details

    2011

    Agarwal S, Jones PS, Alawneh JA, Antoun NM, Barry PJ, Carrera E, Cotter PE, O'Brien EW, Salih I, Scoffings DJ, Baron JC, Warburton EA (2011), “Does perfusion computed tomography facilitate clinical decision making for thrombolysis in unselected acute patients with suspected ischaemic stroke?” Cerebrovasc Dis 32(3):227-33 Details

    Alawneh JA, Jones PS, Mikkelsen IK, Cho TH, Siemonsen S, Mouridsen K, Ribe L, Morris RS, Hjort N, Antoun N, Gillard JH, Fiehler J, Nighoghossian N, Warburton EA, Ostergaard L, Baron JC (2011), “Infarction of 'non-core-non-penumbral' tissue after stroke: multivariate modelling of clinical impact.” Brain 134(Pt 6):1765-76 Details

    Baron JC (2011), “Stroke: Predicting outcome after ischemic stroke-hard but achievable.” Nat Rev Neurol 7(5):253-4 Details

    Bousser MG, Amarenco P, Chamorro A, Fisher M, Ford I, Fox KM, Hennerici MG, Mattle HP, Rothwell PM, de Cordoüe A, Fratacci MD, PERFORM Study Investigators (2011), “Terutroban versus aspirin in patients with cerebral ischaemic events (PERFORM): a randomised, double-blind, parallel-group trial.” Lancet 377(9782):2013-22 Details

    Carrera E, Jones PS, Alawneh JA, Klærke Mikkelsen I, Cho TH, Siemonsen S, Guadagno JV, Mouridsen K, Ribe L, Hjort N, Fryer TD, Carpenter TA, Aigbirhio FI, Fiehler J, Nighoghossian N, Warburton EA, Ostergaard L, Baron JC (2011), “Predicting infarction within the diffusion-weighted imaging lesion: does the mean transit time have added value?” Stroke 42(6):1602-7 Details

    Carrera E, Jones PS, Iglesias S, Guadagno JV, Warburton EA, Fryer TD, Aigbirhio FI, Baron JC (2011), “The vascular mean transit time: a surrogate for the penumbra flow threshold?” J Cereb Blood Flow Metab 31(4):1027-35 Details

    Geva S, Jones PS, Crinion JT, Price CJ, Baron JC, Warburton EA (2011), “The neural correlates of inner speech defined by voxel-based lesion-symptom mapping.” Brain 134(Pt 10):3071-82 Details

    Gregoire SM, Charidimou A, Gadapa N, Dolan E, Antoun N, Peeters A, Vandermeeren Y, Laloux P, Baron JC, Jäger HR, Werring DJ (2011), “Acute ischaemic brain lesions in intracerebral haemorrhage: multicentre cross-sectional magnetic resonance imaging study.” Brain 134(Pt 8):2376-86 Details

    Hong YT, Beech JS, Smith R, Baron JC, Fryer TD (2011), “Parametric mapping of [18F]fluoromisonidazole positron emission tomography using basis functions.” J Cereb Blood Flow Metab 31(2):648-57 Details

    Landt J, D'Abrera JC, Holland AJ, Aigbirhio FI, Fryer TD, Canales R, Hong YT, Menon DK, Baron JC, Zaman SH (2011), “Using positron emission tomography and Carbon 11-labeled Pittsburgh Compound B to image Brain Fibrillar ?-amyloid in adults with down syndrome: safety, acceptability, and feasibility.” Arch Neurol 68(7):890-6 Details

    Mevel K, Desgranges B, Baron JC, Landeau B, de La Sayette V, Viader F, Eustache F, Chételat G (2011), “Which SPM method should be used to extract hippocampal measures in early Alzheimer's disease?” J Neuroimaging 21(4):310-6 Details

    Moustafa RR, Momjian-Mayor I, Jones PS, Morbelli S, Day DJ, Aigbirhio FI, Fryer TD, Warburton EA, Baron JC (2011), “Microembolism versus hemodynamic impairment in rosary-like deep watershed infarcts: a combined positron emission tomography and transcranial Doppler study.” Stroke 42(11):3138-43 Details

    Riss PJ, Hong YT, Williamson D, Caprioli D, Sitnikov S, Ferrari V, Sawiak SJ, Baron JC, Dalley JW, Fryer TD, Aigbirhio FI (2011), “Validation and quantification of [18F]altanserin binding in the rat brain using blood input and reference tissue modeling.” J Cereb Blood Flow Metab 31(12):2334-42 Details

    Takasawa M, Beech JS, Fryer TD, Jones PS, Ahmed T, Smith R, Aigbirhio FI, Baron JC (2011), “Single-subject statistical mapping of acute brain hypoxia in the rat following middle cerebral artery occlusion: a microPET study.” Exp Neurol 229(2):251-8 Details

    2010

    Atack JR, Wong DF, Fryer TD, Ryan C, Sanabria S, Zhou Y, Dannals RF, Eng WS, Gibson RE, Burns HD, Vega JM, Vessy L, Scott-Stevens P, Beech JS, Baron JC, Sohal B, Schrag ML, Aigbirhio FI, McKernan RM, Hargreaves RJ (2010), “Benzodiazepine binding site occupancy by the novel GABAA receptor subtype-selective drug 7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine (TPA023) in rats, primates, and humans.” J Pharmacol Exp Ther 332(1):17-25 Details

    Calautti C, Jones PS, Guincestre JY, Naccarato M, Sharma N, Day DJ, Carpenter TA, Warburton EA, Baron JC (2010), “The neural substrates of impaired finger tapping regularity after stroke.” Neuroimage 50(1):1-6 Details

    Calautti C, Jones PS, Naccarato M, Sharma N, Day DJ, Bullmore ET, Warburton EA, Baron JC (2010), “The relationship between motor deficit and primary motor cortex hemispheric activation balance after stroke: longitudinal fMRI study.” J Neurol Neurosurg Psychiatry 81(7):788-92 Details

    Chételat G, Villemagne VL, Pike KE, Baron JC, Bourgeat P, Jones G, Faux NG, Ellis KA, Salvado O, Szoeke C, Martins RN, Ames D, Masters CL, Rowe CC, Australian Imaging Biomarkers and Lifestyle Study of Ageing (AIBL) Research Group (2010), “Larger temporal volume in elderly with high versus low beta-amyloid deposition.” Brain 133(11):3349-58 Details

    Clatworthy PL, Williams GB, Acosta-Cabronero J, Jones SP, Harding SG, Johansen-Berg H, Baron JC (2010), “Probabilistic tractography of the optic radiations--an automated method and anatomical validation.” Neuroimage 49(3):2001-12 Details

    Hughes JL, Beech JS, Jones PS, Wang D, Menon DK, Baron JC (2010), “Mapping selective neuronal loss and microglial activation in the salvaged neocortical penumbra in the rat.” Neuroimage 49(1):19-31 Details

    Moustafa RR, Izquierdo-Garcia D, Fryer TD, Graves MJ, Rudd JH, Gillard JH, Weissberg PL, Baron JC, Warburton EA (2010), “Carotid plaque inflammation is associated with cerebral microembolism in patients with recent transient ischemic attack or stroke: a pilot study.” Circ Cardiovasc Imaging 3(5):536-41 Details

    Moustafa RR, Izquierdo-Garcia D, Jones PS, Graves MJ, Fryer TD, Gillard JH, Warburton EA, Baron JC (2010), “Watershed infarcts in transient ischemic attack/minor stroke with > or = 50% carotid stenosis: hemodynamic or embolic?” Stroke 41(7):1410-6 Details

    Villain N, Fouquet M, Baron JC, Mézenge F, Landeau B, de La Sayette V, Viader F, Eustache F, Desgranges B, Chételat G (2010), “Sequential relationships between grey matter and white matter atrophy and brain metabolic abnormalities in early Alzheimer's disease.” Brain 133(11):3301-14 Details

    2009

    Alawneh JA, Moustafa RR, Baron JC (2009), “Hemodynamic factors and perfusion abnormalities in early neurological deterioration.” Stroke 40(6):e443-50 Details

    Baron JC (2009), “[Stroke: update on therapy].” Med Sci (Paris) 25(10):771-2 Details

    Bousser MG, Amarenco P, Chamorro A, Fisher M, Ford I, Fox K, Hennerici MG, Mattle HP, Rothwell PM, PERFORM Study Investigators (2009), “Rationale and design of a randomized, double-blind, parallel-group study of terutroban 30 mg/day versus aspirin 100 mg/day in stroke patients: the prevention of cerebrovascular and cardiovascular events of ischemic origin with terutroban in patients with a history of ischemic stroke or transient ischemic attack (PERFORM) study.” Cerebrovasc Dis 27(5):509-18 Details

    Chételat G, Villain N, Desgranges B, Eustache F, Baron JC (2009), “Posterior cingulate hypometabolism in early Alzheimer's disease: what is the contribution of local atrophy versus disconnection?” Brain 132(Pt 12):e133; author reply e134 Details

    Cho TH, Hermier M, Alawneh JA, Ritzenthaler T, Desestret V, Østergaard L, Derex L, Baron JC, Nighoghossian N (2009), “Total mismatch: negative diffusion-weighted imaging but extensive perfusion defect in acute stroke.” Stroke 40(10):3400-2 Details

    Clatworthy PL, Lewis SJ, Brichard L, Hong YT, Izquierdo D, Clark L, Cools R, Aigbirhio FI, Baron JC, Fryer TD, Robbins TW (2009), “Dopamine release in dissociable striatal subregions predicts the different effects of oral methylphenidate on reversal learning and spatial working memory.” J Neurosci 29(15):4690-6 Details

    Cumberland Consensus Working Group, Cheeran B, Cohen L, Dobkin B, Ford G, Greenwood R, Howard D, Husain M, Macleod M, Nudo R, Rothwell J, Rudd A, Teo J, Ward N, Wolf S (2009), “The future of restorative neurosciences in stroke: driving the translational research pipeline from basic science to rehabilitation of people after stroke.” Neurorehabil Neural Repair 23(2):97-107 Details

    Dalley JW, Fryer TD, Aigbirhio FI, Brichard L, Richards HK, Hong YT, Baron JC, Everitt BJ, Robbins TW (2009), “Modelling human drug abuse and addiction with dedicated small animal positron emission tomography.” Neuropharmacology 56 Suppl 1:9-17 Details

    Donnan GA, Baron JC, Ma H, Davis SM (2009), “Penumbral selection of patients for trials of acute stroke therapy.” Lancet Neurol 8(3):261-9 Details

    Donswijk ML, Jones PS, Guadagno JV, Carpenter TA, Moustafa RR, Fryer TD, Aigbirhio FI, Warburton EA, Baron JC (2009), “T2*-weighted MRI versus oxygen extraction fraction PET in acute stroke.” Cerebrovasc Dis 28(3):306-13 Details

    Fouquet M, Desgranges B, Landeau B, Duchesnay E, Mézenge F, de la Sayette V, Viader F, Baron JC, Eustache F, Chételat G (2009), “Longitudinal brain metabolic changes from amnestic mild cognitive impairment to Alzheimer's disease.” Brain 132(Pt 8):2058-67 Details

    Kalpouzos G, Chételat G, Baron JC, Landeau B, Mevel K, Godeau C, Barré L, Constans JM, Viader F, Eustache F, Desgranges B (2009), “Voxel-based mapping of brain gray matter volume and glucose metabolism profiles in normal aging.” Neurobiol Aging 30(1):112-24 Details

    Moustafa RR, Allen CM, Baron JC (2009), “Call-Fleming syndrome associated with subarachnoid haemorrhage: three new cases.” BMJ Case Rep 2009 Details

    Moustafa RR, Izquierdo D, Weissberg PL, Baron JC, Warburton EA (2009), “Identifying aortic plaque inflammation as a potential cause of stroke.” BMJ Case Rep 2009:bcr2007123232 Details

    Pitel AL, Aupée AM, Chételat G, Mézenge F, Beaunieux H, de la Sayette V, Viader F, Baron JC, Eustache F, Desgranges B (2009), “Morphological and glucose metabolism abnormalities in alcoholic Korsakoff's syndrome: group comparisons and individual analyses.” PLoS One 4(11):e7748 Details

    Sharma N, Baron JC, Rowe JB (2009), “Motor imagery after stroke: relating outcome to motor network connectivity.” Ann Neurol 66(5):604-16 Details

    Sharma N, Simmons LH, Jones PS, Day DJ, Carpenter TA, Pomeroy VM, Warburton EA, Baron JC (2009), “Motor imagery after subcortical stroke: a functional magnetic resonance imaging study.” Stroke 40(4):1315-24 Details

    2008

    Auriacombe S, Amarenco P, Baron JC, Ceccaldi M, Dartigues JF, Lehéricy S, Hénon H, Hinaut P, Orgogozo JM, Groupe de consensus Théma (2008), “[Update on vascular dementias].” Rev Neurol (Paris) 164(1):22-41 Details

    Chételat G, Desgranges B, Landeau B, Mézenge F, Poline JB, de la Sayette V, Viader F, Eustache F, Baron JC (2008), “Direct voxel-based comparison between grey matter hypometabolism and atrophy in Alzheimer's disease.” Brain 131(Pt 1):60-71 Details

    Chételat G, Fouquet M, Kalpouzos G, Denghien I, De la Sayette V, Viader F, Mézenge F, Landeau B, Baron JC, Eustache F, Desgranges B (2008), “Three-dimensional surface mapping of hippocampal atrophy progression from MCI to AD and over normal aging as assessed using voxel-based morphometry.” Neuropsychologia 46(6):1721-31 Details

    Giffard C, Landeau B, Kerrouche N, Young AR, Barré L, Baron JC (2008), “Decreased chronic-stage cortical 11C-flumazenil binding after focal ischemia-reperfusion in baboons: a marker of selective neuronal loss?” Stroke 39(3):991-9 Details

    Guadagno JV, Jones PS, Aigbirhio FI, Wang D, Fryer TD, Day DJ, Antoun N, Nimmo-Smith I, Warburton EA, Baron JC (2008), “Selective neuronal loss in rescued penumbra relates to initial hypoperfusion.” Brain 131(Pt 10):2666-78 Details

    Hamon M, Baron JC, Viader F, Hamon M (2008), “Periprocedural stroke and cardiac catheterization.” Circulation 118(6):678-83 Details

    Lees KR, Ford GA, Muir KW, Ahmed N, Dyker AG, Atula S, Kalra L, Warburton EA, Baron JC, Jenkinson DF, Wahlgren NG, Walters MR, SITS-UK Group (2008), “Thrombolytic therapy for acute stroke in the United Kingdom: experience from the safe implementation of thrombolysis in stroke (SITS) register.” QJM 101(11):863-9 Details

    Moustafa RR, Allen CM, Baron JC (2008), “Call-Fleming syndrome associated with subarachnoid haemorrhage: three new cases.” J Neurol Neurosurg Psychiatry 79(5):602-5 Details

    Moustafa RR, Baron JC (2008), “Pathophysiology of ischaemic stroke: insights from imaging, and implications for therapy and drug discovery.” Br J Pharmacol 153 Suppl 1:S44-54 Details

    Moustafa RR, Izquierdo D, Weissberg PL, Baron JC, Warburton EA (2008), “Neurological picture. Identifying aortic plaque inflammation as a potential cause of stroke.” J Neurol Neurosurg Psychiatry 79(2):236 Details

    Piolino P, Desgranges B, Hubert V, Bernard FA, Matuszewski V, Chételat G, Baron JC, Eustache F (2008), “Reliving lifelong episodic autobiographical memories via the hippocampus: a correlative resting PET study in healthy middle-aged subjects.” Hippocampus 18(5):445-59 Details

    SCOPE (Stroke Complications and Outcomes Prediction Engine) Collaborations, IST, Lewis SC, Sandercock PA, Dennis MS (2008), “Predicting outcome in hyper-acute stroke: validation of a prognostic model in the Third International Stroke Trial (IST3).” J Neurol Neurosurg Psychiatry 79(4):397-400 Details

    Sharma N, Jones PS, Carpenter TA, Baron JC (2008), “Mapping the involvement of BA 4a and 4p during Motor Imagery.” Neuroimage 41(1):92-9 Details

    Simmons L, Sharma N, Baron JC, Pomeroy VM (2008), “Motor imagery to enhance recovery after subcortical stroke: who might benefit, daily dose, and potential effects.” Neurorehabil Neural Repair 22(5):458-67 Details

    Takasawa M, Jones PS, Guadagno JV, Christensen S, Fryer TD, Harding S, Gillard JH, Williams GB, Aigbirhio FI, Warburton EA, Østergaard L, Baron JC (2008), “How reliable is perfusion MR in acute stroke? Validation and determination of the penumbra threshold against quantitative PET.” Stroke 39(3):870-7 Details

    Takasawa M, Moustafa RR, Baron JC (2008), “Applications of nitroimidazole in vivo hypoxia imaging in ischemic stroke.” Stroke 39(5):1629-37 Details

    Tang TY, Moustafa RR, Howarth SP, Walsh SR, Boyle JR, Li ZY, Baron JC, Gillard JH, Warburton EA (2008), “Combined PET-FDG and USPIO-enhanced MR imaging in patients with symptomatic moderate carotid artery stenosis.” Eur J Vasc Endovasc Surg 36(1):53-5 Details

    Villain N, Desgranges B, Viader F, de la Sayette V, Mézenge F, Landeau B, Baron JC, Eustache F, Chételat G (2008), “Relationships between hippocampal atrophy, white matter disruption, and gray matter hypometabolism in Alzheimer's disease.” J Neurosci 28(24):6174-81 Details

    Wintermark M, Albers GW, Alexandrov AV, Alger JR, Bammer R, Baron JC, Davis S, Demaerschalk BM, Derdeyn CP, Donnan GA, Eastwood JD, Fiebach JB, Fisher M, Furie KL, Goldmakher GV, Hacke W, Kidwell CS, Kloska SP, Köhrmann M, Koroshetz W, Lee TY, Lees KR, Lev MH, Liebeskind DS, Ostergaard L, Powers WJ, Provenzale J, Schellinger P, Silbergleit R, Sorensen AG, Wardlaw J, Wu O, Warach S (2008), “Acute stroke imaging research roadmap.” AJNR Am J Neuroradiol 29(5):e23-30 Details

    Wintermark M, Albers GW, Alexandrov AV, Alger JR, Bammer R, Baron JC, Davis S, Demaerschalk BM, Derdeyn CP, Donnan GA, Eastwood JD, Fiebach JB, Fisher M, Furie KL, Goldmakher GV, Hacke W, Kidwell CS, Kloska SP, Köhrmann M, Koroshetz W, Lee TY, Lees KR, Lev MH, Liebeskind DS, Ostergaard L, Powers WJ, Provenzale J, Schellinger P, Silbergleit R, Sorensen AG, Wardlaw J, Wu O, Warach S (2008), “Acute stroke imaging research roadmap.” Stroke 39(5):1621-8 Details

    2007

    Atack JR, Scott-Stevens P, Beech JS, Fryer TD, Hughes JL, Cleij MC, Baron JC, Clark JC, Hargreaves RJ, Aigbirhio FI (2007), “Comparison of lorazepam [7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one] occupancy of rat brain gamma-aminobutyric acid(A) receptors measured using in vivo [3H]flumazenil (8-fluoro 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester) binding and [11C]flumazenil micro-positron emission tomography.” J Pharmacol Exp Ther 320(3):1030-7 Details

    Bernard FA, Desgranges B, Eustache F, Baron JC (2007), “Neural correlates of age-related verbal episodic memory decline: a PET study with combined subtraction/correlation analysis.” Neurobiol Aging 28(10):1568-76 Details

    Calautti C, Naccarato M, Jones PS, Sharma N, Day DD, Carpenter AT, Bullmore ET, Warburton EA, Baron JC (2007), “The relationship between motor deficit and hemisphere activation balance after stroke: A 3T fMRI study.” Neuroimage 34(1):322-31 Details

    Dalley JW, Fryer TD, Brichard L, Robinson ES, Theobald DE, Lääne K, Peña Y, Murphy ER, Shah Y, Probst K, Abakumova I, Aigbirhio FI, Richards HK, Hong Y, Baron JC, Everitt BJ, Robbins TW (2007), “Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement.” Science 315(5816):1267-70 Details

    Marié RM, Lozza C, Chavoix C, Defer GL, Baron JC (2007), “Functional imaging of working memory in Parkinson's disease: compensations and deficits.” J Neuroimaging 17(4):277-85 Details

    Mevel K, Desgranges B, Baron JC, Landeau B, De la Sayette V, Viader F, Eustache F, Chételat G (2007), “Detecting hippocampal hypometabolism in Mild Cognitive Impairment using automatic voxel-based approaches.” Neuroimage 37(1):18-25 Details

    Moustafa RR, Baron JC (2007), “Clinical review: Imaging in ischaemic stroke--implications for acute management.” Crit Care 11(5):227 Details

    Salih IS, Higgins NJ, Warburton EA, Baron JC (2007), “Lacunar stroke attributable to radiation-induced intracranial arteriopathy.” Eur J Neurol 14(8):937-9 Details

    Takasawa M, Beech JS, Fryer TD, Hong YT, Hughes JL, Igase K, Jones PS, Smith R, Aigbirhio FI, Menon DK, Clark JC, Baron JC (2007), “Imaging of brain hypoxia in permanent and temporary middle cerebral artery occlusion in the rat using 18F-fluoromisonidazole and positron emission tomography: a pilot study.” J Cereb Blood Flow Metab 27(4):679-89 Details

    U-King-Im JM, Tang T, Moustafa RR, Baron JC, Warburton EA, Gillard JH (2007), “Imaging the cellular biology of the carotid plaque.” Int J Stroke 2(2):85-96 Details

    Yamamoto S, Takasawa M, Kajiyama K, Baron JC, Yamaguchi T (2007), “Deterioration of hemiparesis after recurrent stroke in the unaffected hemisphere: Three further cases with possible interpretation.” Cerebrovasc Dis 23(1):35-9 Details

    2006

    Berkouk K, Quarantelli M, Prinster A, Landeau B, Alfano B, Baron JC (2006), “Mapping the relative contribution of gray matter activity vs. volume in brain PET: a new approach.” J Neuroimaging 16(3):224-35 Details

    Calautti C, Jones PS, Persaud N, Guincestre JY, Naccarato M, Warburton EA, Baron JC (2006), “Quantification of index tapping regularity after stroke with tri-axial accelerometry.” Brain Res Bull 70(1):1-7 Details

    Garosi L, McConnell JF, Platt SR, Barone G, Baron JC, de Lahunta A, Schatzberg SJ (2006), “Clinical and topographic magnetic resonance characteristics of suspected brain infarction in 40 dogs.” J Vet Intern Med 20(2):311-21 Details

    Guadagno JV, Warburton EA, Jones PS, Day DJ, Aigbirhio FI, Fryer TD, Harding S, Price CJ, Green HA, Barret O, Gillard JH, Baron JC (2006), “How affected is oxygen metabolism in DWI lesions?: A combined acute stroke PET-MR study.” Neurology 67(5):824-9 Details

    Hellier KD, Hampton JL, Guadagno JV, Higgins NP, Antoun NM, Day DJ, Gillard JH, Warburton EA, Baron JC (2006), “Perfusion CT helps decision making for thrombolysis when there is no clear time of onset.” J Neurol Neurosurg Psychiatry 77(3):417-9 Details

    Kerrouche N, Herholz K, Mielke R, Holthoff V, Baron JC (2006), “18FDG PET in vascular dementia: differentiation from Alzheimer's disease using voxel-based multivariate analysis.” J Cereb Blood Flow Metab 26(9):1213-21 Details

    Meairs S, Wahlgren N, Dirnagl U, Lindvall O, Rothwell P, Baron JC, Hossmann K, Engelhardt B, Ferro J, McCulloch J, Kaste M, Endres M, Koistinaho J, Planas A, Vivien D, Dijkhuizen R, Czlonkowska A, Hagen A, Evans A, De Libero G, Nagy Z, Rastenyte D, Reess J, Davalos A, Lenzi GL, Amarenco P, Hennerici M (2006), “Stroke research priorities for the next decade--A representative view of the European scientific community.” Cerebrovasc Dis 22(2-3):75-82 Details

    Moustafa RR, Antoun NM, Coulden RA, Warburton EA, Baron JC (2006), “Stroke attributable to a calcific embolus from the brachiocephalic trunk.” Stroke 37(1):e6-8 Details

    Moustafa RR, Baron JC (2006), “Imaging the penumbra in acute stroke.” Curr Atheroscler Rep 8(4):281-9 Details

    Muir KW, Buchan A, von Kummer R, Rother J, Baron JC (2006), “Imaging of acute stroke.” Lancet Neurol 5(9):755-68 Details

    Naccarato M, Calautti C, Jones PS, Day DJ, Carpenter TA, Baron JC (2006), “Does healthy aging affect the hemispheric activation balance during paced index-to-thumb opposition task? An fMRI study.” Neuroimage 32(3):1250-6 Details

    Price CJ, Wang D, Menon DK, Guadagno JV, Cleij M, Fryer T, Aigbirhio F, Baron JC, Warburton EA (2006), “Intrinsic activated microglia map to the peri-infarct zone in the subacute phase of ischemic stroke.” Stroke 37(7):1749-53 Details

    Rauchs G, Blaizot X, Giffard C, Baron JC, Insausti R, Chavoix C (2006), “Imaging visual recognition memory network by PET in the baboon: perirhinal cortex heterogeneity and plasticity after perirhinal lesion.” J Cereb Blood Flow Metab 26(3):301-9 Details

    Salmon E, Kerrouche N, Herholz K, Perani D, Holthoff V, Beuthien-Baumann B, Degueldre C, Lemaire C, Luxen A, Baron JC, Collette F, Garraux G (2006), “Decomposition of metabolic brain clusters in the frontal variant of frontotemporal dementia.” Neuroimage 30(3):871-8 Details

    Sharma N, Pomeroy VM, Baron JC (2006), “Motor imagery: a backdoor to the motor system after stroke?” Stroke 37(7):1941-52 Details

    2005

    Baron JC (2005), “How healthy is the acutely reperfused ischemic penumbra?” Cerebrovasc Dis 20 Suppl 2:25-31 Details

    Baron JC (2005), “Stroke research in the modern era: images versus dogmas.” Cerebrovasc Dis 20(3):154-63 Details

    Baron JC (2005), “Mapping anterograde and retrograde degeneration after stroke.” J Neurol Neurosurg Psychiatry 76(2):159-60 Details

    Baron JC, Warach S (2005), “Imaging.” Stroke 36(2):196-9 Details

    Chételat G, Eustache F, Viader F, De La Sayette V, Pélerin A, Mézenge F, Hannequin D, Dupuy B, Baron JC, Desgranges B (2005), “FDG-PET measurement is more accurate than neuropsychological assessments to predict global cognitive deterioration in patients with mild cognitive impairment.” Neurocase 11(1):14-25 Details

    Chételat G, Landeau B, Eustache F, Mézenge F, Viader F, de la Sayette V, Desgranges B, Baron JC (2005), “Using voxel-based morphometry to map the structural changes associated with rapid conversion in MCI: a longitudinal MRI study.” Neuroimage 27(4):934-46 Details

    Garosi L, McConnell JE, Platt SR, Barone G, Baron JC, de Lahunta A, Schatzberg SJ (2005), “Results of diagnostic investigations and long-term outcome of 33 dogs with brain infarction (2000-2004).” J Vet Intern Med 19(5):725-31 Details

    Giffard C, Young AR, Mézenge F, Derlon JM, Baron JC (2005), “Histopathological effects of delayed reperfusion after middle cerebral artery occlusion in the anesthetized baboon.” Brain Res Bull 67(4):335-40 Details

    Guadagno JV, Warburton EA, Jones PS, Fryer TD, Day DJ, Gillard JH, Carpenter TA, Aigbirhio FI, Price CJ, Baron JC (2005), “The diffusion-weighted lesion in acute stroke: heterogeneous patterns of flow/metabolism uncoupling as assessed by quantitative positron emission tomography.” Cerebrovasc Dis 19(4):239-46 Details

    Guptha SH, Promnitz AD, Warner A, Baron JC (2005), “A 'collapsing' golfer.” Cerebrovasc Dis 19(4):281-2 Details

    Hamon M, Marié RM, Clochon P, Coskun O, Constans JM, Viader F, Courthéoux P, Baron JC (2005), “[Quantitative relationships between ADC and perfusion changes in acute ischemic stroke using combined diffusion-weighted imaging and perfusion MR (DWI/PMR)].” J Neuroradiol 32(2):118-24 Details

    Momjian-Mayor I, Baron JC (2005), “The pathophysiology of watershed infarction in internal carotid artery disease: review of cerebral perfusion studies.” Stroke 36(3):567-77 Details

    Pomeroy VM, Clark CA, Miller JS, Baron JC, Markus HS, Tallis RC (2005), “The potential for utilizing the "mirror neurone system" to enhance recovery of the severely affected upper limb early after stroke: a review and hypothesis.” Neurorehabil Neural Repair 19(1):4-13 Details

    Rodriguez G, Morbelli S, Brugnolo A, Calvini P, Girtler N, Piccardo A, Dougall NJ, Ebmeier KP, Baron JC, Nobili F (2005), “Global cognitive impairment should be taken into account in SPECT-neuropsychology correlations: the example of verbal memory in very mild Alzheimer's disease.” Eur J Nucl Med Mol Imaging 32(10):1186-92 Details

    Schumann-Bard P, Touzani O, Young AR, Toutain J, Baron JC, Mackenzie ET, Schmidt EA (2005), “Cerebrovascular effects of sodium nitroprusside in the anaesthetized baboon: a positron emission tomographic study.” J Cereb Blood Flow Metab 25(4):535-44 Details

    U-King-Im JM, Trivedi RA, Graves MJ, Harkness K, Eales H, Joubert I, Koo B, Antoun N, Warburton EA, Gillard JH, Baron JC (2005), “Utility of an ultrafast magnetic resonance imaging protocol in recent and semi-recent strokes.” J Neurol Neurosurg Psychiatry 76(7):1002-5 Details

    2004

    Baron JC (2004), “Using PET to identify carotid occlusion patients at high risk of subsequent stroke: further insights.” J Neurol Neurosurg Psychiatry 75(12):1659-60 Details

    Baron JC, Cohen LG, Cramer SC, Dobkin BH, Johansen-Berg H, Loubinoux I, Marshall RS, Ward NS, First International Workshop on Neuroimaging and Stroke Recovery (2004), “Neuroimaging in stroke recovery: a position paper from the First International Workshop on Neuroimaging and Stroke Recovery.” Cerebrovasc Dis 18(3):260-7 Details

    Brainin M, Barnes M, Baron JC, Gilhus NE, Hughes R, Selmaj K, Waldemar G, Guideline Standards Subcommittee of the EFNS Scientific Committee (2004), “Guidance for the preparation of neurological management guidelines by EFNS scientific task forces--revised recommendations 2004.” Eur J Neurol 11(9):577-81 Details

    Eustache F, Piolino P, Giffard B, Viader F, De La Sayette V, Baron JC, Desgranges B (2004), “'In the course of time': a PET study of the cerebral substrates of autobiographical amnesia in Alzheimer's disease.” Brain 127(Pt 7):1549-60 Details

    Giffard C, Young AR, Kerrouche N, Derlon JM, Baron JC (2004), “Outcome of acutely ischemic brain tissue in prolonged middle cerebral artery occlusion: a serial positron emission tomography investigation in the baboon.” J Cereb Blood Flow Metab 24(5):495-508 Details

    Guadagno JV, Donnan GA, Markus R, Gillard JH, Baron JC (2004), “Imaging the ischaemic penumbra.” Curr Opin Neurol 17(1):61-7 Details

    Guadagno JV, Warburton EA, Aigbirhio FI, Smielewski P, Fryer TD, Harding S, Price CJ, Gillard JH, Carpenter TA, Baron JC (2004), “Does the acute diffusion-weighted imaging lesion represent penumbra as well as core? A combined quantitative PET/MRI voxel-based study.” J Cereb Blood Flow Metab 24(11):1249-54 Details

    Harkness KA, Coles A, Pohl U, Xuereb JH, Baron JC, Lennox GG (2004), “Rapidly reversible dementia in cerebral amyloid inflammatory vasculopathy.” Eur J Neurol 11(1):59-62 Details

    Lozza C, Baron JC, Eidelberg D, Mentis MJ, Carbon M, Marié RM (2004), “Executive processes in Parkinson's disease: FDG-PET and network analysis.” Hum Brain Mapp 22(3):236-45 Details

    Mahagne MH, David O, Darcourt J, Migneco O, Dunac A, Chatel M, Baron JC (2004), “Voxel-based mapping of cortical ischemic damage using Tc 99m L,L-ethyl cysteinate dimer SPECT in acute stroke.” J Neuroimaging 14(1):23-32 Details

    Mosconi L, Perani D, Sorbi S, Herholz K, Nacmias B, Holthoff V, Salmon E, Baron JC, De Cristofaro MT, Padovani A, Borroni B, Franceschi M, Bracco L, Pupi A (2004), “MCI conversion to dementia and the APOE genotype: a prediction study with FDG-PET.” Neurology 63(12):2332-40 Details

    Piolino P, Giffard-Quillon G, Desgranges B, Chételat G, Baron JC, Eustache F (2004), “Re-experiencing old memories via hippocampus: a PET study of autobiographical memory.” Neuroimage 22(3):1371-83 Details

    Quarantelli M, Berkouk K, Prinster A, Landeau B, Svarer C, Balkay L, Alfano B, Brunetti A, Baron JC, Salvatore M (2004), “Integrated software for the analysis of brain PET/SPECT studies with partial-volume-effect correction.” J Nucl Med 45(2):192-201 Details

    Warach S, Baron JC (2004), “Neuroimaging.” Stroke 35(2):351-3 Details

    2003

    Calautti C, Baron JC (2003), “Functional neuroimaging studies of motor recovery after stroke in adults: a review.” Stroke 34(6):1553-66 Details

    Calautti C, Leroy F, Guincestre JY, Baron JC (2003), “Displacement of primary sensorimotor cortex activation after subcortical stroke: a longitudinal PET study with clinical correlation.” Neuroimage 19(4):1650-4 Details

    Cardebat D, Démonet JF, De Boissezon X, Marie N, Marié RM, Lambert J, Baron JC, Puel M, PET Language Activation Study (2003), “Behavioral and neurofunctional changes over time in healthy and aphasic subjects: a PET Language Activation Study.” Stroke 34(12):2900-6 Details

    Chetelat G, Baron JC (2003), “Early diagnosis of Alzheimer's disease: contribution of structural neuroimaging.” Neuroimage 18(2):525-41 Details

    Chetelat G, Desgranges B, de la Sayette V, Viader F, Berkouk K, Landeau B, Lalevée C, Le Doze F, Dupuy B, Hannequin D, Baron JC, Eustache F (2003), “Dissociating atrophy and hypometabolism impact on episodic memory in mild cognitive impairment.” Brain 126(Pt 9):1955-67 Details

    Chételat G, Desgranges B, de la Sayette V, Viader F, Eustache F, Baron JC (2003), “Mild cognitive impairment: Can FDG-PET predict who is to rapidly convert to Alzheimer's disease?” Neurology 60(8):1374-7 Details

    Greenberg SM, Shin Y, Grabowski TJ, Cooper GE, Rebeck GW, Iglesias S, Chapon F, Tournier-Lasserve E, Baron JC (2003), “Hemorrhagic stroke associated with the Iowa amyloid precursor protein mutation.” Neurology 60(6):1020-2 Details

    Guadagno JV, Calautti C, Baron JC (2003), “Progress in imaging stroke: emerging clinical applications.” Br Med Bull 65:145-57 Details

    Platel H, Baron JC, Desgranges B, Bernard F, Eustache F (2003), “Semantic and episodic memory of music are subserved by distinct neural networks.” Neuroimage 20(1):244-56 Details

    Rocher AB, Chapon F, Blaizot X, Baron JC, Chavoix C (2003), “Resting-state brain glucose utilization as measured by PET is directly related to regional synaptophysin levels: a study in baboons.” Neuroimage 20(3):1894-8 Details

    Rossini PM, Calautti C, Pauri F, Baron JC (2003), “Post-stroke plastic reorganisation in the adult brain.” Lancet Neurol 2(8):493-502 Details

    Zuendorf G, Kerrouche N, Herholz K, Baron JC (2003), “Efficient principal component analysis for multivariate 3D voxel-based mapping of brain functional imaging data sets as applied to FDG-PET and normal aging.” Hum Brain Mapp 18(1):13-21 Details

    2002

    Baron JC (2002), “[Cerebral ischemia--challenges and perspectives].” Therapie 57(6):531-9 Details

    Baron JC (2002), “Stroke: imaging and differential diagnosis.” J Neural Transm Suppl (63):19-36 Details

    Baron JC (2002), “Hippocampal atrophy and neocortical dysfunction in early Alzheimer's disease.” J Neurol Neurosurg Psychiatry 73(5):470-1 Details

    Blaizot X, Meguro K, Millien I, Baron JC, Chavoix C (2002), “Correlations between visual recognition memory and neocortical and hippocampal glucose metabolism after bilateral rhinal cortex lesions in the baboon: implications for Alzheimer's disease.” J Neurosci 22(21):9166-70 Details

    Chavoix C, Blaizot X, Meguro K, Landeau B, Baron JC (2002), “Excitotoxic lesions of the rhinal cortex in the baboon differentially affect visual recognition memory, habit memory and spatial executive functions.” Eur J Neurosci 15(7):1225-36 Details

    Chételat G, Desgranges B, De La Sayette V, Viader F, Eustache F, Baron JC (2002), “Mapping gray matter loss with voxel-based morphometry in mild cognitive impairment.” Neuroreport 13(15):1939-43 Details

    Desgranges B, Baron JC, Giffard B, Chételat G, Lalevée C, Viader F, de la Sayette V, Eustache F (2002), “The neural basis of intrusions in free recall and cued recall: a PET study in Alzheimer's disease.” Neuroimage 17(3):1658-64 Details

    Desgranges B, Baron JC, Lalevée C, Giffard B, Viader F, de La Sayette V, Eustache F (2002), “The neural substrates of episodic memory impairment in Alzheimer's disease as revealed by FDG-PET: relationship to degree of deterioration.” Brain 125(Pt 5):1116-24 Details

    Guillery B, Desgranges B, de la Sayette V, Landeau B, Eustache F, Baron JC (2002), “Transient global amnesia: concomitant episodic memory and positron emission tomography assessment in two additional patients.” Neurosci Lett 325(1):62-6 Details

    Herholz K, Salmon E, Perani D, Baron JC, Holthoff V, Frölich L, Schönknecht P, Ito K, Mielke R, Kalbe E, Zündorf G, Delbeuck X, Pelati O, Anchisi D, Fazio F, Kerrouche N, Desgranges B, Eustache F, Beuthien-Baumann B, Menzel C, Schröder J, Kato T, Arahata Y, Henze M, Heiss WD (2002), “Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET.” Neuroimage 17(1):302-16 Details

    Lozza C, Marié RM, Baron JC (2002), “The metabolic substrates of bradykinesia and tremor in uncomplicated Parkinson's disease.” Neuroimage 17(2):688-99 Details

    Millien I, Blaizot X, Giffard C, Mézenge F, Insausti R, Baron JC, Chavoix C (2002), “Brain glucose hypometabolism after perirhinal lesions in baboons: implications for Alzheimer disease and aging.” J Cereb Blood Flow Metab 22(10):1248-61 Details

    2001

    Aupée AM, Desgranges B, Eustache F, Lalevée C, de la Sayette V, Viader F, Baron JC (2001), “Voxel-based mapping of brain hypometabolism in permanent amnesia with PET.” Neuroimage 13(6 Pt 1):1164-73 Details

    Baron JC (2001), “Mapping the ischaemic penumbra with PET: a new approach.” Brain 124(Pt 1):2-4 Details

    Baron JC, Chételat G, Desgranges B, Perchey G, Landeau B, de la Sayette V, Eustache F (2001), “In vivo mapping of gray matter loss with voxel-based morphometry in mild Alzheimer's disease.” Neuroimage 14(2):298-309 Details

    Bernard F, Desgranges B, Platel H, Baron JC, Eustache F (2001), “Contributions of frontal and medial temporal regions to verbal episodic memory: a PET study.” Neuroreport 12(8):1737-41 Details

    Calautti C, Leroy F, Guincestre JY, Baron JC (2001), “Dynamics of motor network overactivation after striatocapsular stroke: a longitudinal PET study using a fixed-performance paradigm.” Stroke 32(11):2534-42 Details

    Calautti C, Leroy F, Guincestre JY, Marié RM, Baron JC (2001), “Sequential activation brain mapping after subcortical stroke: changes in hemispheric balance and recovery.” Neuroreport 12(18):3883-6 Details

    Eustache F, Desgranges B, Giffard B, de la Sayette V, Baron JC (2001), “Entorhinal cortex disruption causes memory deficit in early Alzheimer's disease as shown by PET.” Neuroreport 12(4):683-5 Details

    Lebreton K, Desgranges B, Landeau B, Baron JC, Eustache F (2001), “Visual priming within and across symbolic format using a tachistoscopic picture identification task: a PET study.” J Cogn Neurosci 13(5):670-86 Details

    Meguro K, LeMestric C, Landeau B, Desgranges B, Eustache F, Baron JC (2001), “Relations between hypometabolism in the posterior association neocortex and hippocampal atrophy in Alzheimer's disease: a PET/MRI correlative study.” J Neurol Neurosurg Psychiatry 71(3):315-21 Details