Dr Giulia Bonetto
Department of Veterinary Medicine
MRC Cambridge Stem Cell Institute
Cognitive and Behavioural Neuroscience
Studies of neural circuit plasticity focus almost exclusively on functional and structural changes of neuronal synapses. In recent years, however, myelin plasticity has emerged as a potential modulator of neuronal networks. Indeed, myelination of previously unmyelinated axons and changes in the structure on already-myelinated axons can have large effects on the function of neuronal networks.
As myelin plasticity is increasingly being implicated as a mechanism for sensory-motor and non-motor learning, my goal is to investigate the role of myelin in the context of complex cognitive learning tasks. I am doing so by using a cutting-edge multi-disciplinary approach combining behavioural experiments, confocal and two-photon microscopy, molecular biology, immunohistochemistry, histology and transgenics.
Electrophysiological recording techniques
Recombinant protein expression
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