Dr Frank Reimann

University position

Reader

Dr Frank Reimann is pleased to consider applications from prospective PhD students.

Departments

Department of Clinical Biochemistry

Institutes

Institute of Metabolic Science

Home page

http://www.mrl.ims.cam.ac.uk/staff/F...

Research Theme

Cellular and Molecular Neuroscience

The Cambridge Neuroscience Community

Interests

Research in the lab is currently focusing on enteroendocrine cells, especially glucagon-like peptide-1 (GLP-1) secreting cells, which we hope to target in the treatment of diabetes and obesity. GLP-1 secreting cells are electrically excitable and respond to changes in ambient nutrient supply through electrogenic uptake and an increase in action potential firing frequency. We also started to work on GLP-1 target cells including enteric and affarent autonomic neurons. In addition we have a longstanding interest in nociception, characterising ion channel mutations found by Geoff Woods group in inherited pain disorders.

Research Focus

Keywords

enteroendocrine

ion channels

diabetes

obesity

nociception

Clinical conditions

Diabetes

Eating disorders

Hormonal disorders

Pain disorders

Equipment

Calcium imaging

Cell culture

Confocal microscopy

Electrophysiological recording techniques

Enzyme assays

Fluorescence microscopy

Immunohistochemistry

Microscopy

Whole cell patch clamp

Collaborators

Cambridge

Fiona Gribble

Geoff Woods

United Kingdom

Stefan Trapp Web: http://iris.ucl.ac.uk/iris/br...