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Research Focus

Keywords

  • Axon Regeneration
  • Neuronal Cell Biology
  • Axonal Transport
  • Clinical Conditions

  • Glaucoma
  • Spinal cord injury
  • Equipment & Techniques

  • Cell culture
  • Microscopy
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    Fiona Love

    (she/her/hers)
    University Position
    PhD student
    Research Associate

    Interests

    Adult CNS neurons have marked differences in axon transport compared to their peripheral or developing counterparts. As a result, adult CNS axons often lack the molecular machinery needed to survive and recover from injury or disease. I'm investigating how the axon transport and localisation of particular proteins and organelles is linked to regenerative ability, and how we can target this transport as a potential treatment avenue for glaucoma and other forms of CNS injury and disease.

    Key Publications

    Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS.

    DOI: http://doi.org/10.1038/s41467-020-19436-y
    Journal: Nat Commun
    E-pub date: 5 Nov 2020
    Authors: V Petrova, CS Pearson, J Ching, JR Tribble, AG Solano, Y Yang, FM Love, RJ Watt, A Osborne, E Reid, PA Williams, KR Martin, HM Geller, R Eva, JW Fawcett

    Publications