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I study the cognitive and neural mechanisms with which we plan and control action, in health and after the development of dementia. The control of action depends on the integration of predicted consequences of action with sensory information, modulated by experience. As the brain changes with normal ageing or disease (such as dementia), the essential sensorimotor integration and the use of experience are impaired. In addition to affecting learning and control of action, a consequence of these changes can be apathy. I use psychophysical and cognitive tools, in combination with modelling and neuroimaging, to develop a mechanistic account of apathy.
Magnetic resonance imaging (MRI)
Associated News Items
Savulich G, Hezemans FH, van Ghesel Grothe S, Dafflon J, Schulten N, Brühl AB, Sahakian BJ, Robbins TW (2019), “Acute anxiety and autonomic arousal induced by CO2 inhalation impairs prefrontal executive functions in healthy humans” Transl Psychiatry 9