Dr Emma Cahill University positionAffiliated Lecturer DepartmentsDepartment of Physiology, Development and Neuroscience InstitutesBehavioural and Clinical Neuroscience Institute Home pagehttps://www.pdn.cam.ac.uk/directo... Research ThemesInterestsMy immediate objective is to develop my research in neuronal signalling complexes and apply what I find to unanswered fundamental questions related to memory and adaptive behaviour. In my research, I address the signalling requirements of memories associated with drugs of abuse, appetitive experience and also memories of fear. More recently, I have become interested in the relationship of fear and anxiety, and how the two maybe supported by neurochemically and anatomically distinct mechanisms. Research Focus
EquipmentBehavioural analysis Fluorescence microscopy Immunohistochemistry Microscopy Collaborators
Associated News ItemsPublications2020Taujanskaite U, Cahill EN, Milton AL (2020), “Targeting drug memory reconsolidation: a neural analysis” Current Opinion in Pharmacology 2019Cahill EN, Milton AL (2019), “Neurochemical and molecular mechanisms underlying the retrieval-extinction effect” Psychopharmacology 1-22 2018Cahill, E. N., Wood, M. A., Everitt, B. J., & Milton, A. L. (2018), “The role of prediction error and memory destabilization in extinction of cued-fear within the reconsolidation window.” Neuropsychopharmacology 2017Cahill EN, Vousden GH, Exton-McGuinness MTJ, Beh IRC, Swerner CB, Macak M, Abas S, Cole CC, Kelleher BF, Everitt BJ, Milton AL (2017), “Limbic zif268 expression engaged by reactivation of a rewarded T-maze task memory is not required for stable performance” Neuroscience Dos Santos M, Cahill EN, Bo GD, Vanhoutte P, Caboche J, Giros B, Heck N. (2017), ““Cocaine increases dopaminergic boutons density in the nucleus accumbens.”” Brain Struct Funct 2014Cahill E, Pascoli V, Trifilieff P, Savoldi D, Kappès V, Lüscher C, Caboche J, Vanhoutte P (2014), “D1R/GluN1 complexes in the striatum integrate dopamine and glutamate signalling to control synaptic plasticity and cocaine-induced responses.” Mol Psychiatry 19(12):1295-304 Details Cahill E, Salery M, Vanhoutte P, Caboche J (2014), “Convergence of dopamine and glutamate signaling onto striatal ERK activation in response to drugs of abuse.” Front Pharmacol 4:172 Details Pascoli V, Cahill E, Bellivier F, Caboche J, Vanhoutte P (2014), “Extracellular Signal-Regulated Protein Kinases 1 and 2 Activation by Addictive Drugs: A Signal Toward Pathological Adaptation.” Biol Psychiatry Details 2011Roze E, Cahill E, Martin E, Bonnet C, Vanhoutte P, Betuing S, Caboche J (2011), “Huntington's Disease and Striatal Signaling.” Front Neuroanat 5:55 Details 2008Larkin AE, Fahey B, Gobbo O, Callaghan CK, Cahill E, O'Mara SM, Kelly AM (2008), “Blockade of NMDA receptors pre-training, but not post-training, impairs object displacement learning in the rat.” Brain Res 1199:126-32 Details |