Dr Emad Moeendarbary University positionHerchel Smith Research Fellow DepartmentsDepartment of Physiology, Development and Neuroscience Home pagehttp://www.MecBioMed.com (personal home page) Research ThemesInterestsI am a mechanical engineer with a strong interest in the experimental and theoretical/computational study of biological systems. Presently, I am working at the interface of engineering and neuroscience to explore mechanics of neurons in the central nervous system. I am also interested in the mechanobiology of cancer metastasis.  AFM cantilever with a spherical tip indenting a cell Click image to view full-size Research Focus
EquipmentAtomic Force Microscopy Computational modelling Defocusing Microscopy Microfluidics Parallel Programming Traction Force Microscopy Collaborators
Associated News ItemsPublications2015Gautier HO, Thompson AJ, Achouri S, Koser DE, Holtzmann K, Moeendarbary E, Franze K (2015), “Atomic force microscopy-based force measurements on animal cells and tissues.” Methods Cell Biol 125:211-35 Details Moeendarbary E, Charras G (2015), “Cell mechanics: Hydraulic cracking.” Nat Mater 14(3):268-9 Details 2014Moeendarbary E, Harris AR (2014), “Cell mechanics: principles, practices, and prospects.” Wires SYSTEMS BIOLOGY AND MEDICINE Vol 6 (Issue5) PDF Sheridan GK, Moeendarbary E, Pickering M, O'Connor JJ, Murphy KJ (2014), “Theta-burst stimulation of hippocampal slices induces network-level calcium oscillations and activates analogous gene transcription to spatial learning.” PLoS One 9(6):e100546 Details 2013Calvo F, Ege N, Grande-Garcia A, Hooper S, Jenkins RP, Chaudhry SI, Harrington K, Williamson P, Moeendarbary E, Charras G, Sahai E (2013), “Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.” Nat Cell Biol Details Moeendarbary E, Valon L, Fritzsche M, Harris AR, Moulding DA, Thrasher AJ, Stride E, Mahadevan L, Charras GT (2013), “The cytoplasm of living cells behaves as a poroelastic material.” Nat Mater 12(3):253-61 Details 2012Kunda P, Rodrigues NT, Moeendarbary E, Liu T, Ivetic A, Charras G, Baum B (2012), “PP1-mediated moesin dephosphorylation couples polar relaxation to mitotic exit.” Curr Biol 22(3):231-6 PDF Details Moulding DA, Moeendarbary E, Valon L, Record J, Charras GT, Thrasher AJ (2012), “Excess F-actin mechanically impedes mitosis leading to cytokinesis failure in X-linked neutropenia by exceeding Aurora B kinase error correction capacity.” Blood 120(18):3803-11 PDF Details 2010Moeendarbary E, Ng TY, Pan H, Lam KY (2010), “Migration of DNA molecules through entropic trap arrays: A dissipative particle dynamics study” Microfluidics and Nanofluidics 8(2):243-254 PDF Moeendarbary E, Ng TY, Zangeneh M (2010), “Dissipative particle dynamics in soft matter and polymeric applications” International Journal of Applied Mechanics 2(1):161-190 PDF Pan H, Ng TY, Li H, Moeendarbary E (2010), “Dissipative particle dynamics simulation of entropic trapping for DNA separation” Sensors and Actuators, A: Physical 157(2):328-335 PDF 2009Moeendarbary E, Ng TY, Zangeneh M (2009), “Dissipative particle dynamics: Introduction, methodology and complex fluid applications-a review” International Journal of Applied Mechanics 1(4):737-763 PDF |