Edward Avezov University positionGroup Leader, UK Dementia Research Institute Fellow Edward Avezov is pleased to consider applications from prospective PhD students. DepartmentsDepartment of Clinical Neurosciences InstitutesUK Dementia Research Institute at University of Cambridge Home pagehttp://avezov-lab.neurosciences.medsc... (personal home page) Research ThemeInterestsThrough an in-depth investigation of the neuronal cell biophysical properties, our program aims to Identify new targetable pathways, disrupted in dementia. In particular, we seek understanding of the role Endoplasmic Reticulum, and its structure function regulation, plays in neuronal (patho)physiology, and thus to gain insight into the dementia-underlying dysregulation of ER function. In our quests we develop, implement and combine techniques such as high tempora-spatial resolution light microscopy (super-resolution), genetically encoded biosensors, genetic manipulations of neuronal models (e.g. iPS cells based) and in vitro/in vivo biochemistry. Research Focus
EquipmentCalcium imaging Computational modelling Fluorescence microscopy Live cell super-resolution & single molecule tracking, calcium imaging, Microscopy Recombinant protein expression Collaborators
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