Mr Emre Fertan

University position

PhD student
Supervised by Professor Sir David Klenerman


Department of Chemistry


UK Dementia Research Institute at University of Cambridge

Home page

Research Themes

Cellular and Molecular Neuroscience

Cognitive and Behavioural Neuroscience


I have a background in behavioural neuroscience, during which I studied the behavioural and neuropathological changes in mouse models of Alzheimer's disease. My current work focuses on characterising cellular (iPSC and organoid systems), synaptosome, and animal models of neurodegenerative diseases using super-resolution microscopy techniques.

Research Focus


Alzheimer's disease

Cellular models

Mouse models


Super-resolution microscopy

Clinical conditions

Alzheimer's disease



Parkinson's disease


Behavioural analysis

Cell culture

Enzyme assays

Fluorescence microscopy


Recombinant protein expression



Gabriel Balmus

Jack Brelstaff

Maria Grazia Spillantini

United Kingdom

Bart De Strooper Web:

Dean Nizetic Web:

Rickie Patani Web:


Richard Brown Web:

Ian Weaver Web:

Associated News Items

    Key publications

    Gendron WH, Fertan E, Pelletier S, Roddick KM, O’Leary TP, Anini Y, Brown RE   (2021), “Age related weight loss in female 5xFAD mice from 3 to 12 months of age” Behav Brain Res 406:113214.

    Fertan E, Wong AA, Purdon KM, Weaver ICG, Brown RE (2020), “The effect of background strain on the behavioural phenotypes of the MDGA2+/- mouse model of autism spectrum disorder.” Genes Brain Behav. e12696

    Fertan E, Rodrigues G, Wheeler R, Gaugen D, Wong AA, James H, Stadnyk A, Brown RE, Weaver ICG (2019), “Cognitive decline, cerebral-spleen tryptophan metabolism, cytokine production and regulation of the Txnip gene in 3xTg-AD mice” Am J Pathol. 189(7):1435-1450

    Fertan E, Stover KRJ, Brant MG, Stafford PM, Kelly B, Diez-Cecilia E, Wong AA, Weaver DF, Brown RE (2019), “ Effects of the novel IDO inhibitor DWG-1036 on the behavior of male and female 3xTg-AD mice” Front Pharmacol 10:1044

    Fertan E, Wong AA, Vienneau NW, Brown RE (2019), “Age and sex differences in motivation and spatial working memory in 3xTg-AD mice in the Hebb-Williams maze” Behav Brain Res 370:111937



    Fertan E, Brown RE (2022), “Age-related deficits in working memory in 5xFAD mice in the Hebb-Williams maze” Behav Brain Res 424:113806


    Simanaviciute U, Ahmed J, Brown RE, Connor-Robson N, Farr TD, Fertan E, Gambles N, Garland H, Morton JA, Staiger JF, Skillings EA, Trueman RC, Wade-Martins R, Wood NI, Wong AA, Grant RA (2020), “Recommendations for measuring whisker movements and locomotion in mice with motor, sensory and cognitive deficits ” J Neurosci Methods 331:108532.


    Garvock-de Montbrun T, Fertan E, Stover K, Brown RE (2019), “Motor deficits in 16-month-old male and female 3xTg-AD mice” Behav Brain Res 356:305-313

    Gur E, Fertan E, Alkins K, Aimee AA, Brown RE, Balci F (2019), “Interval timing is altered in the 5xFAD mice: meditation of memory processes. ” J Neurosci Res.  97(7):817-827

    Gur E, Fertan E, Kosel F, Wong AA, Balci F, Brown RE (2019), “Sex differences in the timing behavior performance of 3xTg-AD and Wild-Type mice in the peak interval procedure” Behav Brain Res 15(360):235-243


    Grant R, Wong AA, Fertan E, Brown RE (2018), “hisker exploration behaviours in the 5xFAD mouse are affected by sex and retinal degeneration.” Genes Brain Behav. e12532

    Kane AE, Shin S, Wong AA, Fertan E, Faustova N, Howlett SE, Brown RE (2018), “Sex differences in healthspan predict lifespan in the 3xTg-AD mouse model of Alzheimer’s disease” Front Aging Neurosci. 10:172


    O’Leary TP, Shin S, Fertan E, Dingle RN, Almuklass A, Gunn RK, Yu Z, Wang J, Brown RE (2017), “Reduced acoustic startle response and peripheral hearing loss in the 5xFAD mouse model of Alzheimer’s disease.” Genes Brain Behav. 16(5): 554-563