Mr Emre Fertan University positionPhD student DepartmentsInstitutesUK Dementia Research Institute at University of Cambridge Home pagehttps://www.klenermangroup.co.uk/ Research ThemesInterestsI have a background in behavioural neuroscience, during which I studied the behavioural and neuropathological changes in mouse models of Alzheimer's disease. My current work focuses on characterising cellular (iPSC and organoid systems), synaptosome, and animal models of neurodegenerative diseases using super-resolution microscopy techniques. Research Focus
EquipmentBehavioural analysis Cell culture Enzyme assays Fluorescence microscopy Microscopy Recombinant protein expression Collaborators
Associated News ItemsKey publicationsGendron WH, Fertan E, Pelletier S, Roddick KM, O’Leary TP, Anini Y, Brown RE (2021), “Age related weight loss in female 5xFAD mice from 3 to 12 months of age” Behav Brain Res 406:113214. Fertan E, Wong AA, Purdon KM, Weaver ICG, Brown RE (2020), “The effect of background strain on the behavioural phenotypes of the MDGA2+/- mouse model of autism spectrum disorder.” Genes Brain Behav. e12696 Fertan E, Rodrigues G, Wheeler R, Gaugen D, Wong AA, James H, Stadnyk A, Brown RE, Weaver ICG (2019), “Cognitive decline, cerebral-spleen tryptophan metabolism, cytokine production and regulation of the Txnip gene in 3xTg-AD mice” Am J Pathol. 189(7):1435-1450 Fertan E, Stover KRJ, Brant MG, Stafford PM, Kelly B, Diez-Cecilia E, Wong AA, Weaver DF, Brown RE (2019), “ Effects of the novel IDO inhibitor DWG-1036 on the behavior of male and female 3xTg-AD mice” Front Pharmacol 10:1044 Fertan E, Wong AA, Vienneau NW, Brown RE (2019), “Age and sex differences in motivation and spatial working memory in 3xTg-AD mice in the Hebb-Williams maze” Behav Brain Res 370:111937 Publications2022Fertan E, Brown RE (2022), “Age-related deficits in working memory in 5xFAD mice in the Hebb-Williams maze” Behav Brain Res 424:113806 2020Simanaviciute U, Ahmed J, Brown RE, Connor-Robson N, Farr TD, Fertan E, Gambles N, Garland H, Morton JA, Staiger JF, Skillings EA, Trueman RC, Wade-Martins R, Wood NI, Wong AA, Grant RA (2020), “Recommendations for measuring whisker movements and locomotion in mice with motor, sensory and cognitive deficits ” J Neurosci Methods 331:108532. 2019Garvock-de Montbrun T, Fertan E, Stover K, Brown RE (2019), “Motor deficits in 16-month-old male and female 3xTg-AD mice” Behav Brain Res 356:305-313 Gur E, Fertan E, Alkins K, Aimee AA, Brown RE, Balci F (2019), “Interval timing is altered in the 5xFAD mice: meditation of memory processes. ” J Neurosci Res. 97(7):817-827 Gur E, Fertan E, Kosel F, Wong AA, Balci F, Brown RE (2019), “Sex differences in the timing behavior performance of 3xTg-AD and Wild-Type mice in the peak interval procedure” Behav Brain Res 15(360):235-243 2018Grant R, Wong AA, Fertan E, Brown RE (2018), “hisker exploration behaviours in the 5xFAD mouse are affected by sex and retinal degeneration.” Genes Brain Behav. e12532 Kane AE, Shin S, Wong AA, Fertan E, Faustova N, Howlett SE, Brown RE (2018), “Sex differences in healthspan predict lifespan in the 3xTg-AD mouse model of Alzheimer’s disease” Front Aging Neurosci. 10:172 2017O’Leary TP, Shin S, Fertan E, Dingle RN, Almuklass A, Gunn RK, Yu Z, Wang J, Brown RE (2017), “Reduced acoustic startle response and peripheral hearing loss in the 5xFAD mouse model of Alzheimer’s disease.” Genes Brain Behav. 16(5): 554-563 |