Dr Daniel Sobrido-Cameán

Interests

During my PhD, I have been carrying out studies using lampreys as an animal model for spinal cord injury. Lampreys are a good model of regeneration/plasticity. But, also has some limitations. For example, their life cycle takes between 5 and 7 years from birth to sexual maturity. Therefore, it is highly impractical to generate stable mutant or transgenic lines in the laboratory. In contrast to lampreys, the fruit-fly, Drosophila, is genetically tractable and there are tools and innovations in genetic, imaging, and electrophysiological technologies that have enabled the visualization, in vivo, of dynamic processes such as dendritic growth and synapse development. For this reason, I joined to the group of Dr Matthias Landgraf, who has extensive experience in the use of drosophila as a model for the study of the development of the nervous system. In the long run, I want to harness the genetics of Drosophila to identify candidate pathways and genes involved in nervous system development.

Research Focus

Keywords

development

drosophila

nervous system

ROS

Clinical conditions

No direct clinical relevance

Equipment

Behavioural analysis

Calcium imaging

Confocal microscopy

Fluorescence microscopy

Immunohistochemistry

Microscopy

Collaborators

No collaborators listed

Associated News Items


    Publications

    2021

    Sobrido-Cameán D, Yáñez-Guerra L, Deber A, Freire-Delgado M, Cacheiro-Vázquez R, Rodicio MC, Tostivint H, Anadón R, Barreiro-Iglesias A (2021), “Differential expression of three somatostatin genes in the central nervous system of the sea lamprey” Brain Structure and Function

    2020

    Da Silva-Álvarez S, Guerra-Varela J, Sobrido-Cameán D, Quelle A, Barreiro-Iglesias A, Sánchez L, Collado M (2020), “Developmentally-programmed cellular senescence is conserved and widespread in zebrafish” Aging

    Sobrido-Cameán D, Robledo D, Romaus-Sanjurjo D, Perez-Cedrón C, Sánchez L, Rodicio MC, Barreiro-Iglesias A (2020), “Inhibition of gamma-secretase promotes axon regeneration after a complete spinal cord injury.” Frontiers in Cell and Developmental Biology

    Sobrido-Cameán D, Tostivint H, Mazan S, Rodicio MC, Rodríguez-Moldes I, Candal E, Anadón R, Barreiro-Iglesias A (2020), “In situ hybridization study of the differential expression of five prosomatostatin genes in the central nervous system of the catshark Scyliorhinus canicula” Journal of Comparative Neurology

    2019

    Da Silva-Álvarez S, Guerra-Varela J, Sobrido-Cameán D, Quelle A, Barreiro-Iglesias A, Sánchez L, Collado M (2019), “Cell senescence contributes to tissue regeneration in Zebrafish” Aging Cell

    Sobrido-Cameán D, Yáñez-Guerra LA, Robledo D, López-Varela E, Rodicio MC, Elphick MR, Anadón R, Barreiro-Iglesias A (2019), “Cholecystokinin in the central nervous system of the sea lamprey Petromyzon marinus: precursor identification and neuroanatomical relationships with other neuronal signalling systems” Brain Structure and Function

    Sobrido-Cameán D, Fernández-López B, Pereiro N, Lafuente A, Rodicio MC, Barreiro-Iglesias A (2019), “Taurine promotes axonal regeneration after a complete spinal cord injury in lampreys” Journal of Neurotrauma

    Sobrido-Cameán D, Robledo D, Sánchez L, Rodicio MC, Barreiro-Iglesias A (2019), “Serotonin inhibits axonal regeneration of identifiable descending neurons after a complete spinal cord injury in lampreys” Disease Models and Mechanisms

    Sobrido-Cameán D, Yáñez-Guerra LA, Lamanna F, Conde-Fernández C, Kaessmann H, Elphick MR, Anadón R, Rodicio MC, Barreiro-Iglesias A (2019), “Galanin in an agnathan: precursor identification and localisation of expression in the brain of the sea lamprey Petromyzon marinus” Frontiers in Neuroanatomy

    2018

    Sobrido-Cameán D, Barreiro-Iglesias A (2018), “Role of caspase-8 and Fas in cell death after spinal cord injury” Frontiers in Molecular Neuroscience

    Sobrido-Cameán D, Rodicio MC, Barreiro-Iglesias A (2018), “The role of serotonin in nervous system regeneration: lessons from regenerating animal models” Neural Regeneration Research

    Sobrido-Cameán D, Rodicio MC, Barreiro-Iglesias A (2018), “Data on the effect of a muscimol treatment in caspase activation in descending neurons of lampreys after a complete spinal cord injury” Data in Brief

    2017

    Barreiro-Iglesias A, Fernández-López B, Sobrido-Cameán D, Anadón R (2017), “ Organization of AlphaTransducin Immunoreactive System in the Brain and Retina of Larval and Young Adult Sea Lamprey (Petromyzon marinus), and their Relationship with Other Neural Systems” Journal of Comparative Neurology

    Barreiro-Iglesias A, Sobrido-Cameán D, Shifman MI (2017), “Retrograde activation of the extrinsic apoptotic pathway in spinal-projecting neurons after a complete spinal cord injury in lampreys” BioMed Research International

    Fernández-López B, Sobrido-Cameán D, Anadón R, Rodicio MC, Barreiro-Iglesias A (2017), “Restricted co-localization of glutamate and dopamine in neurons of the adult sea lamprey brain” Journal of Anatomy

    Romaus-Sanjurjo, D, Fernández-López, B, Sobrido-Cameán, D, Barreiro-Iglesias, A, Rodicio, MC (2017), “Cloning of the gabaB Receptor Subunits B1 and B2 and their Expression in the Central Nervous System of the Adult Sea Lamprey” Frontiers in Neuroanatomy