Dr Paul Miller


University position

Lecturer

Dr Paul Miller is pleased to consider applications from prospective PhD students.

Departments

Department of Pharmacology

Home page

https://www.phar.cam.ac.uk/directo...

Research Theme

Cellular and Molecular Neuroscience

Interests

I use electrophysiology and structural biology to understand GABA-A receptors and ligands that target them. I am also using these approaches to develop novel pharmacological tools against GABA-A receptor signalling and to study these tools in physiological systems. This work encompasses developing stabilized forms of GABA-A receptors for use in pharmacological assays.

Research Focus

Keywords

GABA

Crystallography

CryoEM

Pharmacology

Nanobody

Clinical conditions

Anxiety disorders

Equipment

Cell culture

CryoEM

Electrophysiological recording techniques

Fluorescence microscopy

FPLC/HPLC

Protein purification

Recombinant protein expression

Whole cell patch clamp

X-ray crystallography

Collaborators

No collaborators listed

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